Molecular characterization of the Caenorhabditis elegans Rho GDP‐dissociation inhibitor

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Rho GTPases and signaling networks

1997 • 2,380 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

Regulation of Phagocyte Oxygen Radical Production by the GTP-Binding Protein Rac 2

1991 • 669 citations

The pharynx of Caenorhabditis elegans

1976 • 649 citations

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway.

1996 • 601 citations

Rho GTPases

1998 • 534 citations

Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia.

1995 • 418 citations

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

1993 • 319 citations

Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins.

1990 • 314 citations

Purification and characterization from bovine brain cytosol of a novel regulatory protein inhibiting the dissociation of GDP from and the subsequent binding of GTP to rhoB p20, a ras p21-like GTP-binding protein.

1990 • 277 citations

Role of a New Rho Family Member in Cell Migration and Axon Guidance in C. elegans

1997 • 251 citations

Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins.

1994 • 245 citations

Sperm morphogenesis in wild-type and fertilization-defective mutants of Caenorhabditis elegans.

1981 • 205 citations

The Rho Small G Protein Family-Rho GDI System as a Temporal and Spatial Determinant for Cytoskeletal Control

1998 • 200 citations

Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes.

1993 • 192 citations

The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein

1992 • 175 citations

The small GTP-binding proteins in the cytosol of insulin-secreting cells are complexed to GDP dissociation inhibitor proteins.

1992 • 174 citations

C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases

1997 • 169 citations

A GDP Dissociation Inhibitor That Serves as a GTPase Inhibitor for the Ras-Like Protein CDC42Hs

1992 • 164 citations

Caenorhabditis elegans spermatozoan locomotion: amoeboid movement with almost no actin.

1982 • 159 citations

Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product.

1991 • 148 citations

Spermatogenesis in males of the free-living nematode, Caenorhabditis elegans

1978 • 147 citations

cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins.

1993 • 137 citations

Characterization of the Interaction between RhoGDI and Cdc42Hs Using Fluorescence Spectroscopy

1996 • 129 citations

GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein.

1993 • 125 citations

RhoGDI-3 Is a New GDP Dissociation Inhibitor (GDI)

1996 • 117 citations

RhoGDIγ: A GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas

1997 • 102 citations

The Caenorhabditis elegans spe-26 gene is necessary to form spermatids and encodes a protein similar to the actin-associated proteins kelch and scruin.

1995 • 91 citations

Molecular cloning and characterization of yeast rho GDP dissociation inhibitor.

1994 • 86 citations

Consequences of weak interaction of rho GDI with the GTP-bound forms of rho p21 and rac p21.

1993 • 75 citations

CDC43 and RAM2 encode the polypeptide subunits of a yeast type I protein geranylgeranyltransferase.

1992 • 65 citations

The CDC42 homologue from Caenorhabditis elegans. Complementation of yeast mutation

1993 • 61 citations

The Caenorhabditis elegans p21-activated Kinase (CePAK) Colocalizes with CeRac1 and CDC42Ce at Hypodermal Cell Boundaries during Embryo Elongation

1996 • 61 citations

Role of the rac1 p21‐GDP‐dissociation inhibitor for rho heterodimer in the activation of the superoxide‐forming NADPH oxidase of macrophages

1993 • 49 citations

Identification of a novel protein with GDP dissociation inhibitor activity for the ras‐like proteins CDC42Hs and Rac 1

1993 • 41 citations

The Caenorhabditis elegans small GTP-binding protein RhoA is enriched in the nerve ring and sensory neurons during larval development.

1994 • 38 citations

A new member of the ras superfamily, the rac1 homologue from Caenorhabditis elegans. Cloning and sequence analysis of cDNA, pattern of developmental expression, and biochemical characterization of the protein.

1993 • 36 citations

Characterization of a promiscuous GTPase-activating protein that has a Bcr-related domain from Caenorhabditis elegans.

1994 • 24 citations

Regulation of actin cytoskeleton by Rho-family GTPases and their associated proteins

1996 • 22 citations

Isolation of the gene coding for Caenorhabditis elegans Rac2 homologue, a Ras-related small GTP-binding protein

1996 • 10 citations