Relationship of actin polymerization and depolymerization to light scattering in human neutrophils: dependence on receptor occupancy and intracellular Ca++.

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

1982 • 2,255 citations

Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factors.

1977 • 905 citations

Actin polymerization and its regulation by proteins from nonmuscle cells.

1982 • 739 citations

Mechanism of action of cytochalasin B on actin

1980 • 732 citations

Chemotactic peptide modulation of actin assembly and locomotion in neutrophils.

1984 • 359 citations

Protein kinase C activation of physiological processes in human neutrophils at vanishingly small cytosolic Ca2+ levels

1984 • 334 citations

A quantitative fluorimetric assay for the determination of oxidant production by polymorphonuclear leukocytes: Its use in the simultaneous fluorimetric assay of cellular activation processes

1984 • 322 citations

Direct measurement of actin polymerization rate constants by electron microscopy of actin filaments nucleated by isolated microvillus cores.

1981 • 298 citations

Cytochalasin inhibits the rate of elongation of actin filament fragments

1979 • 295 citations

Cell polarity: an examination of its behavioral expression and its consequences for polymorphonuclear leukocyte chemotaxis.

1981 • 263 citations

Modulation of cytosolic-free calcium transients by changes in intracellular calcium-buffering capacity: correlation with exocytosis and O2-production in human neutrophils.

1984 • 262 citations

Kinetics of the cooperative association of actin to actin filament

1975 • 244 citations

Stimulation of human neutrophils by soluble and insoluble immunoglobulin aggregates. Secretion of granule constituents and increased oxidation of glucose.

1975 • 206 citations

Sensory adaptation of leukocytes to chemotactic peptides.

1979 • 190 citations

Chemotactic reorientation of granulocytes stimulated with micropipettes containing fmet-leu-phe

1981 • 187 citations

Chemotactic peptide-induced changes in neutrophil actin conformation.

1984 • 186 citations

The dynamics of ligand-receptor interactions. Real-time analyses of association, dissociation, and internalization of an N-formyl peptide and its receptors on the human neutrophil.

1984 • 178 citations

F actin assembly modulated by villin: Ca++-dependent nucleation and capping of the barbed end

1981 • 167 citations

Changes in cytoskeletal proteins of polymorphonuclear leukocytes induced by chemotactic peptides

1983 • 153 citations

Actin polymerization induced by chemotactic peptide and concanavalin A in rat neutrophils.

1982 • 122 citations

Changing patterns of plasma membrane-associated filaments during the initial phases of polymorphonuclear leukocyte adherence.

1979 • 117 citations

A continuous, spectroscopic analysis of the kinetics of elastase secretion by neutrophils. The dependence of secretion upon receptor occupancy.

1982 • 108 citations

Membrane activity and topography of F-Met-Leu-Phe-Treated polymorphonuclear leukocytes. Acute and sustained responses to chemotactic peptide.

1982 • 82 citations

The kinetics of neutrophil activation. The response to chemotactic peptides depends upon whether ligand-receptor interaction is rate-limiting.

1981 • 74 citations

Analysis of ligand-receptor interactions with the fluorescence activated cell sorter

1982 • 73 citations

Fluoresceinated chemotactic peptide and high-affinity antifluorescein antibody as a probe of the temporal characteristics of neutrophil stimulation.

1981 • 71 citations

Stimulus response coupling in the human neutrophil. Differential requirements for receptor occupancy in neutrophil responses to a chemoattractant.

1984 • 68 citations

Rapid changes in light scattering from human polymorphonuclear leukocytes exposed to chemoattractants. Discrete responses correlated with chemotactic and secretory functions.

1984 • 63 citations

Neutrophil degranulation detected by right angle light scattering: spectroscopic methods suitable for simultaneous analyses of degranulation or shape change, elastase release, and cell aggregation.

1984 • 59 citations

The Neutrophil N-Formyl Peptide Receptor: Dynamics of Ligand-Receptor Interactions and Their Relationship to Cellular Responses

1984 • 53 citations

The synthetic chemotactic peptide formyl-methionyl-leucylphenylalanine causes an increase in actin associated with the cytoskeleton in rabbit neutrophils

1982 • 43 citations

Tubulin tyrosinolation in human polymorphonuclear leukocytes: studies in normal subjects and in patients with the Chediak-Higashi syndrome.

1982 • 42 citations

Actin Gelation and the Structure of Cortical Cytoplasm

1982 • 39 citations

A convenient on‐line device for reagent addition, sample mixing, and temperature control of cell suspensisons in flow cytometry

1985 • 30 citations

Light‐scattering changes during chemotactic stimulation of human neutrophils: Kinetics followed by flow cytometry

1985 • 24 citations