Recombinant IL-10 and IL-10/Fc treatment down-regulate egg antigen-specific delayed hypersensitivity reactions and egg granuloma formation in schistosomiasis.

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

1991 • 1,950 citations

A Manual of Methods for Baculovirus Vectors and Insect Cell Culture Procedures.

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B70 antigen is a second ligand for CTLA-4 and CD28

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Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni.

1991 • 777 citations

Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI.

1991 • 752 citations

Effects of IL-12 on in vivo cytokine gene expression and Ig isotype selection.

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Different T helper cell subsets elicited in mice utilizing two different adjuvant vehicles: The role of endogenous interleukin 1 in proliferative responses

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Mild prolonged schistosomiasis in mice

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Immune Responses to a Soluble Schistosomal Egg Antigen Preparation during Chronic Primary Infection with Schistosoma Mansoni

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The cell-mediated response to schistosomal antigens at the clonal level. In vivo functions of cloned murine egg antigen-specific CD4+ T helper type 1 lymphocytes.

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Accessory cell signals regulate Th-cell responses: from basic immunology to a model of helminthic disease

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