Alkalinization of the lysosomes is correlated with ras transformation of murine and human fibroblasts.

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight.

1980 • 809 citations

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.

1980 • 743 citations

Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.

1982 • 569 citations

The pH dependence of fluorescein fluorescence

1975 • 529 citations

Mannose 6-Phosphate Receptors and Lysosomal Enzyme Targeting

1989 • 473 citations

L-Fucose-terminated glycoconjugates are recognized by pinocytosis receptors on macrophages.

1981 • 181 citations

The endocytosis of epidermal growth factor in A431 cells: A pH of microenvironment and the dynamics of receptor complex dissociation

1988 • 88 citations

Malignant transformation of human fibroblasts caused by expression of a transfected T24 HRAS oncogene.

1989 • 73 citations

Intracellular processing of epidermal growth factor and its effect on ligand-receptor interactions.

1985 • 71 citations

Role of the degradation process in the mitogenic effect of epidermal growth factor

1980 • 61 citations

Nuclear transport in 3T3 fibroblasts: effects of growth factors, transformation, and cell shape.

1988 • 57 citations

Primary amines induce selective release of lysosomal enzymes from mouse macrophages

1980 • 56 citations

Secretion and uptake of ß-N-acetylglucosaminidase by fibroblasts Effect of chloroquine and mannose 6-phosphate

1979 • 35 citations

Fluorescence photobleaching assay of tumor promoter 12-O-tetradecanoylphorbol 13-acetate inyibition of cell-cell communication

1987 • 16 citations