Evaluation of Immunohistochemical Staining and Activity of Thymidylate Synthase in Cell Lines

In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas.

1982 • 254 citations

Interaction of gamma interferon and 5-fluorouracil in the H630 human colon carcinoma cell line.

1990 • 182 citations

Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells.

1985 • 154 citations

Elevation of thymidylate synthase following 5-fluorouracil treatment is prevented by the addition of leucovorin in murine colon tumors.

1992 • 121 citations

Clinical relevance of biochemical modulation of 5-fluorouracil

1991 • 108 citations

Radiotherapy versus combined modality in early stages

1992 • 32 citations

Human lymphoblastoid cells with acquired resistance to C2-desamino-C2-methyl-N10-propargyl-5,8-dideazafolic acid: a novel folate-based thymidylate synthase inhibitor.

1992 • 23 citations