Resistance to influenza virus and vesicular stomatitis virus conferred by expression of human MxA protein

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

GTP-binding domain: three consensus sequence elements with distinct spacing.

1987 • 602 citations

Mx protein: Constitutive expression in 3T3 cells transformed with cloned Mx cDNA confers selective resistance to influenza virus

1986 • 479 citations

Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle

1989 • 474 citations

Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2α kinase

1986 • 358 citations

Homology of 54K protein of signal-recognition particle, docking protein and two E. coli proteins with putative GTP–binding domains

1989 • 357 citations

Interferon-Induced Proteins and the Antiviral State

1990 • 353 citations

Interferon-activated genes

1986 • 301 citations

cDNA structures and regulation of two interferon-induced human Mx proteins.

1989 • 300 citations

The signal recognition particle receptor mediates the GTP-dependent displacement of SRP from the signal sequence of the nascent polypeptide

1989 • 293 citations

Constitutive expression of (2′–5′) oligo A synthetase confers resistance to picornavirus infection

1987 • 277 citations

Influenza Virus-Susceptible Mice Carry Mx Genes with a Large Deletion or a Nonsense Mutation

1988 • 264 citations

Role of interferon in the pathogenesis of virus diseases in mice as demonstrated by the use of anti-interferon serum. I. Rapid evolution of encephalomyocarditis virus infection.

1976 • 254 citations

Inhibition of influenza viral mRNA synthesis in cells expressing the interferon-induced Mx gene product

1985 • 159 citations

Topology of signal recognition particle receptor in endoplasmic reticulum membrane

1985 • 140 citations

Interferon-induced protein Mx accumulates in nuclei of mouse cells expressing resistance to influenza viruses

1985 • 123 citations

cDNA Structures and Regulation of Two Interferon-Induced Human Mx Proteins

1989 • 118 citations

Cloning and sequence analyses of cDNAs for interferon- and virus-induced human Mx proteins reveal that they contain putative guanine nucleotide-binding sites: functional study of the corresponding gene promoter

1990 • 116 citations

Interferon-induced human protein with homology to protein Mx of influenza virus-resistant mice.

1985 • 92 citations

Interferon-induced Mx protein: a mediator of cellular resistance to influenza virus.

1987 • 87 citations

Mechanisms of the Antiviral Action of Interferons

1988 • 86 citations

Antiviral state against influenza virus neutralized by microinjection of antibodies to interferon-induced Mx proteins.

1988 • 86 citations

A family of interferon-induced Mx-related mRNAs encodes cytoplasmic and nuclear proteins in rat cells

1988 • 84 citations

A ubiquitous mammalian expression vector, pHMG, based on a housekeeping gene promoter

1989 • 81 citations

Inhibition of vesicular stomatitis viral mRNA synthesis by interferons

1987 • 78 citations

Polyclonal and monoclonal antibodies to the interferon-inducible protein Mx of influenza virus-resistant mice.

1985 • 77 citations

IFN-αInduced Human 78 kD Protein: Purification and Homologies with the Mouse Mx Protein, Production of Monoclonal Antibodies, and Potentiation Effect of IFN-γ

1987 • 71 citations

Transport of the Murine Mx Protein into the Nucleus Is Dependent on a Basic Carboxy-Terminal Sequence

1987 • 66 citations

Rhabdovirus Biology and Infection

1987 • 57 citations

Combined action of mouse alpha and beta interferons in influenza virus-infected macrophages carrying the resistance gene Mx

1984 • 49 citations

Mechanism of interferon action: inhibition of vesicular stomatitis virus replication in human amnion U cells by cloned human leukocyte interferon. II. Effect on viral macromolecular synthesis.

1983 • 47 citations

Interferon-Induced Human Protein with Homology to Protein Mx of Influenza Virus-Resistant Mice

1985 • 27 citations

Preliminary characterization of the particles from productive and abortive infections of L cells by fowl plague virus.

1979 • 17 citations

Purification and Characterization of a Human Mx Protein

1989 • 17 citations