A multilocus extension of the affected-pedigree-member method of linkage analysis.

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1991 • 4,533 citations

Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21

1990 • 2,505 citations

The investigation of linkage between a quantitative trait and a marker locus

1972 • 1,398 citations

The Genetic Defect Causing Familial Alzheimer's Disease Maps on Chromosome 21

1987 • 1,149 citations

Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage.

1991 • 762 citations

The affected-pedigree-member method of linkage analysis.

1988 • 493 citations

Computer-simulation methods in human linkage analysis.

1989 • 492 citations

Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder

1990 • 396 citations

The generalized sib pair IBD distribution: its use in the detection of linkage

1978 • 244 citations

HLA-UNKED GENETIC CONTROL OF HOST RESPONSE TO MYCOBACTERIUM LEPRÆ

1976 • 188 citations

Disease Susceptibility Genes ‐ their Identification by Multiple Case Family Studies

1976 • 155 citations

Sibling Method for Detecting HLA‐Linked Genes in Disease

1977 • 150 citations

A simple method to detect linkage for rare recessive diseases: An application to juvenile diabetes

1979 • 96 citations

Mapping autosomal recessive vitamin D dependency type I to chromosome 12q14 by linkage analysis.

1990 • 93 citations

A recursive algorithm for the calculation of identity coefficients

1981 • 90 citations

A robust method for the detection of linkage in familial disease.

1978 • 56 citations

Determining the mode of inheritance of RFLP-associated diseases using the affected sib-pair method.

1986 • 39 citations

Two-locus and Three-locus Gene Identity by Descent in Pedigrees

1988 • 30 citations

Studies of a DNA marker (G8) genetically linked to Huntington disease in British families

1986 • 27 citations

Linkage Methods for Identifying Genetic Risk Factors1

2015 • 9 citations

The distribution of HLA haplotypes in families with one untyped parent

1982 • 6 citations

Genetic epidemiology of bilateral breast cancer: A linkage analysis using the affected‐pedigree‐member method

1990 • 4 citations