Back to search

Peroxisomal Straight-chain Acyl-CoA Oxidase and D-bifunctional Protein Are Essential for the Retroconversion Step in Docosahexaenoic Acid Synthesis

Data up to Jan 2025

Published2001
Citations98
References45

Total Citations Per Year

Abstract

References (45)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Chemistry and metabolism of lipids in the vertebrate retina

1983 • 1,034 citations

Essential fatty acids in growth and development

1991 • 945 citations

Biochemical and functional effects of prenatal and postnatal omega 3 fatty acid deficiency on retina and brain in rhesus monkeys.

1986 • 922 citations

Peroxisomal and Mitochondrial Defects in the Cerebro-Hepato-Renal Syndrome

1973 • 777 citations

Lipids of nervous tissue: Composition and metabolism

1985 • 725 citations

The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase.

1991 • 660 citations

Reevaluation of the pathways for the biosynthesis of polyunsaturated fatty acids.

1995 • 510 citations

A unified nomenclature for peroxisome biogenesis factors.

1996 • 413 citations

A Possible Essential Role for Dietary Linolenic Acid in the Development of the Young Rat

1976 • 367 citations

Components Involved in Peroxisome Import, Biogenesis, Proliferation, Turnover, and Movement

1998 • 331 citations

The desaturation step in the animal biosynthesis of polyunsaturated fatty acids

1971 • 228 citations

Peroxisomal bifunctional enzyme deficiency.

1989 • 208 citations

Rats with low levels of brain docosahexaenoic acid show impaired performance in olfactory‐based and spatial learning tasks

1999 • 192 citations

X-linked adrenoleukodystrophy: genes, mutations, and phenotypes.

1999 • 182 citations

Sterol carrier protein X is peroxisomal 3-oxoacyl coenzyme A thiolase with intrinsic sterol carrier and lipid transfer activity.

1994 • 175 citations

Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid

1995 • 160 citations

Biochemical abnormalities in rhizomelic chondrodysplasia punctata

1988 • 133 citations

Lipid metabolism in peroxisomes in relation to human disease

1998 • 123 citations

Alkyl-Dihydroxyacetonephosphate Synthase

1998 • 114 citations

Peroxisomal Bifunctional Protein Deficiency Revisited: Resolution of Its True Enzymatic and Molecular Basis

1999 • 103 citations

Genotype–Phenotype Correlations in Disorders of Peroxisome Biogenesis

1999 • 98 citations

Plasma and red blood cell fatty acids in peroxisomal disorders.

1999 • 93 citations

Secondary carnitine deficiency and impaired docosahexaenoic (22:6n‐3) acid synthesis: a common denominator in the pathophysiology of diseases of oxidative phosphorylation and β‐oxidation

2000 • 92 citations

Peroxisomal disorders: clinical, biochemical, and molecular aspects.

1999 • 77 citations

Peroxisomal beta-oxidation enzymes.

1999 • 76 citations

Polyunsaturated fatty acid biosynthesis: a microsomal-peroxisomal process

1999 • 63 citations

Polyunsaturated fatty acid metabolism in retinal and cerebral microvascular endothelial cells.

1997 • 62 citations

Analysis of the putative role of 24‐carbon polyunsaturated fatty acids in the biosynthesis of docosapentaenoic (22:5n‐6) and docosahexaenoic (22:6n‐3) acids

1998 • 60 citations

On the molecular etiology of decreased arachidonic (20:4n-6), docosapentaenoic (22:5n-6) and docosahexaenoic (22:6n-3) acids in Zellweger syndrome and other peroxisomal disorders.

1997 • 59 citations

Polyunsaturated fatty acids in the developing human brain, erythrocytes and plasma in peroxisomal disease: therapeutic implications

1995 • 55 citations

Lipid metabolism in peroxisomes: enzymology, functions and dysfunctions of the fatty acid α- and β-oxidation systems in humans

2000 • 55 citations

Impaired Arachidonic (20:4n-6) and Docosahexaenoic (22:6n-3) Acid Synthesis by Phenylalanine Metabolites as Etiological Factors in the Neuropathology of Phenylketonuria

2001 • 52 citations

Mutants of theYarrowia lipolytica PEX23Gene Encoding an Integral Peroxisomal Membrane Peroxin Mislocalize Matrix Proteins and Accumulate Vesicles Containing Peroxisomal Matrix and Membrane Proteins

2000 • 47 citations

Rhizomelic chondrodysplasia punctata, a peroxisomal biogenesis disorder caused by defects in Pex7p, a peroxisomal protein import receptor: a minireview.

1999 • 47 citations

Ether lipid synthesis and its deficiency in peroxisomal disorders

1993 • 43 citations

Polyunsaturated fatty acids in human nutrition

1993 • 41 citations

The pathway from arachidonic to docosapentaenoic acid (20:4n-6 to 22:5n-6) and from eicosapentaenoic to docosahexaenoic acid (20:5n-3 to 22:6n-3) studied in testicular cells from immature rats

2000 • 41 citations

Pristanic acid and phytanic acid in plasma from patients with peroxisomal disorders: stable isotope dilution analysis with electron capture negative ion mass fragmentography.

1992 • 40 citations

Simultaneous Measurement of Desaturase Activities Using Stable Isotope Tracers or a Nontracer Method

1998 • 37 citations

Are ω-3 Fatty Acids Required for Normal Eye and Brain Development in the Human?

1990 • 34 citations

Peroxisomal Acyl-Coenzyme A Oxidase Is a Rate-Limiting Enzyme in a Very Long-Chain Fatty Acid β-Oxidation System

1994 • 33 citations

Zellweger Syndrome Knockout Mouse Models Challenge Putative Peroxisomal β-Oxidation Involvement in Docosahexaenoic Acid (22:6n-3) Biosynthesis

2001 • 28 citations

A comparison of the metabolism of [3-14C]-labeled 22- and 24-carbon (n−3) and (n−6) unsaturated fatty acids by rat testes and liver

1999 • 16 citations

Beta-oxidation of long-chain fatty acids by human fibroblasts: Evidence for a novel long-chain acyl-coenzyme a dehydrogenase

1992 • 13 citations

Cited By (0)

Loading...
Peroxisomal Straight-chain Acyl-CoA Oxidase and D-bifunctional Protein Are Essential for… (2001) – Journal of Biological Chemistry | Metascience Observatory Explorer