The desaturation step in the animal biosynthesis of polyunsaturated fatty acids

ADVANCES IN LIPID RESEARCH

1966 • 1,199 citations

Effect of Saturated and Unsaturated Fatty Acids on the Desaturation in Vitro of Palmitic, Stearic, Oleic, Linoleic, and Linolenic Acids

1966 • 406 citations

Electron-transfer mechanism associated with fatty acid desaturation catalyzed by liver microsomes

1966 • 285 citations

Study of biological structure at the molecular level with stereomodel projections I. The lipids in the myelin sheath of nerve

1963 • 271 citations

On the orientation of lipids in chloroplast and cell membranes

1966 • 247 citations

Lipids of subcellular particles

1965 • 227 citations

The intracellular localization of an enzymatic defect of lipid metabolism in diabetic rats

1964 • 216 citations

Long Chain Fatty Acid Activation in Subcellular Preparations from Rat Liver

1968 • 200 citations

NUTRITIONAL AND METABOLIC INTERRELATIONSHIPS BETWEEN FATTY ACIDS.

1964 • 198 citations

The preferred metabolic pathway from linoleic acid to arachidonic acid in vitro

1968 • 161 citations

A Requirement for Lipids by the Microsomal Stearyl Coenzyme A Desaturase

1969 • 158 citations

Role of lipids in the structure and function of biological membranes

1966 • 153 citations

Regulation of unsaturated fatty acids biosynthesis 1. Effect of unsaturated fatty acid of 18 carbons on the microsomal desaturation of linoleic acid into γ-linolenic acid

1969 • 147 citations

Differential responses to fasting and subsequent feeding by microsomal systems of rat liver: 6- and 9-desaturation of fatty acids

1969 • 141 citations

THE ROLE OF LONG-RANGE FORCES IN THE COHESION OF LIPOPROTEINS

1962 • 128 citations

Depression of microsomal desaturation of linoleictoy-linolenicacid in the alloxan-diabetic rat

1966 • 123 citations

Requirement for Reduced Diphosphopyridine Nucleotide-Cytochrome b5 Reductase in Stearyl Coenzyme A Desaturation

1970 • 114 citations

Effect of arachidonic acid in the alloxan-diabetic rat

1968 • 92 citations

Metabolism of the Geometric Isomers of Linoleic Acid in the Rat

1967 • 80 citations

The stereochemistry of desaturations of long-chain fatty acids in Chlorella vulgaris

1968 • 73 citations

Effect of diet on linoleic acid desaturation and on some enzymes of carbohydrate metabolism

1970 • 71 citations

Effect of insulin on the oxidative desaturation ofa‐linolenic, oleic and palmitic acids

1967 • 70 citations

The relationship of single dietary polyunsaturated fatty acids to fatty acid composition of lipids from subcellular particles of liver

1964 • 65 citations

Metabolism of fatty acids of the linoleic acid series in testicles of diabetic rats

1970 • 57 citations

Inhibitory effect of docosa-4,7,10,13,16,19-hexaenoicacid upon the oxidative desaturation of linoleic into γ-linolenic acid and of α-linolenic into octadeca-6,9,12,15-tetraenoic acid

1967 • 56 citations

The effects of trans, trans-linoleate upon the metabolism of linoleate and linolenate and the positional distribution of linoleate isomers in liver lecithin

1965 • 55 citations

Assay and Isolation of a Cyanide-binding Protein of Rat Liver Microsomes

1970 • 49 citations

THE ROLE OF LONG-RANGE FORCES IN THE COHESION OF LIPOPROTEINS

1962 • 49 citations

The metabolism of polyenoic fatty acids

1965 • 46 citations

Competitive effect of alpha- and gamma-lionlenyl-CoA in linoleyl-CoA desaturation to gamma-linolenyl-CoA.

1969 • 44 citations

Competitive effect of α- and γ-linolenyl-CoA and arachidonyl-CoA in linoleyl-CoA desaturation to γ-linolenyl-CoA

1969 • 41 citations

Effect of arachidonic acid on the microsomal desaturation of linoleic into γ-linolenic acid and their simultaneous incorporation into the phospholipids

1968 • 39 citations

Preliminary Partial Purification of Hen Liver Microsomal Stearoyl‐CoA Desaturase

1970 • 31 citations

Reciprocal interactions in the desaturation of linoleic acid into γ‐linolenic and eicosa‐8,11,14‐trienoic into arachidonic

1969 • 30 citations

The Metabolism of Polyenoic Fatty Acids

1965 • 28 citations

Comparative effects of docosa‐4,7,10,13,16‐pentaenoic acid and docosa‐4,7,10,13,16,19‐hexaenoic acid on the desaturation of linoleic acid and α‐linolenic acid

1970 • 25 citations

Metabolic conversions and the positional distributions in liver lecithin of some unnatural dienoic acids in the rat

1967 • 25 citations

Conversion of C17 polyenoic acids into more highly unsaturated acids by the rat

1964 • 22 citations

“Solubilization” of the stearoyl‐CoA desaturase of rat liver microsomes

1968 • 15 citations

Nonconversion of 5,11,14‐eicosatrienoic into arachidonic acid by rats

1970 • 13 citations

Rate of linoleic and arachidonic acid incorporation into liver, heart and red cells of essential fatty acid deficient rats and its effect on eicosatrienoic acid depletion.

1965 • 4 citations

[Effect of insulin on the lipids of subcellular fractions of rat's liver].

1969 • 1 citations