The alpha-adrenergic stimulation of atrial natriuretic factor expression in cardiac myocytes requires calcium influx, protein kinase C, and calmodulin-regulated pathways

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

CREB: a Ca ²⁺ -Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases

1991 • 1,476 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1988 • 1,278 citations

Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB

1990 • 1,061 citations

Role of ion flux in the control of c-fos expression

1986 • 1,006 citations

Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy

1990 • 641 citations

Alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. fos/jun expression is associated with sarcomere assembly; Egr-1 induction is primarily an alpha 1-mediated response.

1990 • 444 citations

Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences.

1988 • 404 citations

Hydrophobic regions function in calmodulin-enzyme(s) interactions.

1980 • 363 citations

Actions of sympathomimetic amines on the Ca2+ transients and contractions of rabbit myocardium: reciprocal changes in myofibrillar responsiveness to Ca2+ mediated through alpha- and beta-adrenoceptors.

1988 • 337 citations

Alpha 1-adrenergic and muscarinic cholinergic stimulation of phosphoinositide hydrolysis in adult rat cardiomyocytes.

1985 • 298 citations

Neonatal atria and ventricles secrete atrial natriuretic factor via tissue-specific secretory pathways

1986 • 283 citations

A protein kinase C isozyme is translocated to cytoskeletal elements on activation.

1990 • 257 citations

Co-regulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during alpha-adrenergic stimulation of neonatal rat ventricular cells. Identification of cis sequences within an embryonic and a constitutive contractile protein gene which mediate inducible expression.

1991 • 244 citations

Rapid ionic modifications during the aequorin-detected calcium transient in a skinned canine cardiac Purkinje cell.

1985 • 192 citations

Differential acute and chronic response of protein kinase C in cultured neonatal rat heart myocytes to α1-adrenergic and phorbol ester stimulation

1988 • 185 citations

Calcium as a modulator of the immediate-early gene cascade in neurons

1988 • 179 citations

The homeostasis of calcium in heart cells

1985 • 174 citations

Quantitative measurement of sn-1,2-diacylglycerols

1987 • 166 citations

Thyrotropin-releasing hormone induces redistribution of protein kinase C in GH4C1 rat pituitary cells.

1985 • 140 citations

The effect of depolarization on expression of the human proenkephalin gene is synergistic with cAMP and dependent upon a cAMP-inducible enhancer

1990 • 123 citations

Participation of voltage-sensitive calcium channels in pituitary hormone release.

1988 • 122 citations

N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), a calmodulin antagonist, also inhibits phospholipid sensitive calcium-dependent protein kinase

1983 • 93 citations

Identification of highly conserved regulatory domains and protein-binding sites in the promoters of the rat and human genes encoding the stress-inducible 78-kilodalton glucose-regulated protein.

1988 • 92 citations

The secretion of atrial natriuretic factor-(99-126) by cultured cardiac myocytes is regulated by glucocorticoids.

1988 • 87 citations

Cis-acting sequences that modulate atrial natriuretic factor gene expression.

1988 • 85 citations

Alpha-1 adrenergic stimulation of 1,4,5-inositol trisphosphate formation in ventricular myocytes.

1989 • 73 citations

Effects of steroid and thyroid hormones on synthesis of atrial natriuretic peptide by cultured atrial myocytes of rat

1987 • 71 citations

Extracellular calcium regulates expression of the gene for atrial natriuretic factor.

1990 • 68 citations

Endothelin stimulates accumulations for cellular atrial natriuretic peptide and its messenger RNA in rat cardiocytes

1989 • 66 citations

Guanine nucleotide-dependent inositol trisphosphate formation in chick heart cells.

1988 • 64 citations

Thyroid Hormone Increases Rat Atrial Natriuretic Peptide Messenger Ribonucleic Acid Accumulationin Vivoandin Vitro*

1987 • 64 citations

Proximal Upstream Flanking Sequences Direct Calcium Regulation of the Rat Prolactin Gene

1988 • 61 citations

N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide, a novel activator of protein kinase C

1986 • 53 citations

Tissue-specific Determinants of Human Atrial Natriuretic Factor Gene Expression in Cardiac Tissue

1989 • 49 citations

Upstream sequences confer atrial-specific expression on the human atrial natriuretic factor gene.

1988 • 49 citations

The calcium agonist Bay K 8644 stimulates secretion from a pituitary cell line

1984 • 40 citations

Calcium Channel Agonists and Antagonists: Effects of Chronic Treatment on Pituitary Prolactin Synthesis and Intracellular Calcium

1988 • 37 citations

Ca2+ potentiates cAMP-dependent expression of urokinase-type plasminogen activator gene through a calmodulin- and protein kinase C-independent mechanism.

1990 • 33 citations

Thyroid hormone stimulates rat pro-natriodilatin mRNA levels in primary cardiocyte cultures

1987 • 30 citations

Ventricular myocytes from neonatal rats are more responsive to dexamethasone than atrial myocytes in synthesis of atrial natriuretic peptide

1987 • 29 citations

Ca²⁺ Regulates Hormone Secretion and Proopiomelanocortin Gene Expression in Melanotrope Cells via the Calmodulin and the Protein Kinase C Pathways

1989 • 28 citations

Spontaneous and experimentally evoked [Ca2+]i-transients in cardiac myocytes measured by means of a fast Fura-2 technique

1990 • 27 citations

Stimulation of adrenocorticotropin secretion from AtT-20 cells by the calcium channel activator, BAY-K-8644, and its inhibition by somatostatin and carbachol.

1985 • 24 citations

Mechanisms of action of inhibitors of prolactin secretion in GH3 pituitary cells. II. Blockade of voltage-dependent Ca2+ channels.

1986 • 11 citations

Calcium and calmodulin regulation of prolactin gene expression

1990 • 3 citations