Frequent Detection of Escape from Cytotoxic T-Lymphocyte Recognition in Perinatal Human Immunodeficiency Virus (HIV) Type 1 Transmission: the Ariel Project for the Prevention of Transmission of HIV from Mother to Infant

1993 Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS Among Adolescents and Adults

1993 • 3,829 citations

Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus Type 1 with Zidovudine Treatment

1994 • 3,642 citations

Avoiding false positives with PCR

1989 • 3,564 citations

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

1994 • 2,529 citations

HIV Population Dynamics in Vivo: Implications for Genetic Variation, Pathogenesis, and Therapy

1995 • 1,997 citations

Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection

1994 • 1,899 citations

MHC ligands and peptide motifs: first listing

1995 • 1,674 citations

A TH1→TH2 switch is a critical step in the etiology of HIV infection

1993 • 1,403 citations

The role of a mutant CCR5 allele in HIV–1 transmission and disease progression

1996 • 1,364 citations

Antiviral pressure exerted by HIV-l-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

1997 • 1,206 citations

Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

1997 • 1,135 citations

Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition

1991 • 1,025 citations

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes

1998 • 1,012 citations

1993 Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS Among Adolescents and Adults

1993 • 968 citations

Maternal Viral Load, Zidovudine Treatment, and the Risk of Transmission of Human Immunodeficiency Virus Type 1 from Mother to Infant

1996 • 812 citations

Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection

1997 • 696 citations

Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics.

1995 • 650 citations

1993 Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS Among Adolescents and Adults

1993 • 606 citations

Selective Transmission of Human Immunodeficiency Virus Type-1 Variants from Mothers to Infants

1992 • 598 citations

Adaptive Evolution of Human Immunodeficiency Virus-Type 1 During the Natural Course of Infection

1996 • 578 citations

Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

1994 • 545 citations

High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors

1995 • 519 citations

Obstetrical Factors and the Transmission of Human Immunodeficiency Virus Type 1 from Mother to Child

1996 • 446 citations

Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants

1994 • 418 citations

HIV-specific cytotoxic T-cell activity in an HIV-exposed but uninfected infant

1993 • 368 citations

Suppression of human immunodeficiency virus type 1 replication by CD8+ cells: evidence for HLA class I-restricted triggering of cytolytic and noncytolytic mechanisms

1997 • 345 citations

Cytotoxic T lymphocytes in asymptomatic long-term nonprogressing HIV-1 infection. Breadth and specificity of the response and relation to in vivo viral quasispecies in a person with prolonged infection and low viral load.

1996 • 330 citations

Genetic differences between blood- and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequences

1994 • 329 citations

Molecular cloning and characterization of the HTLV-III virus associated with AIDS

1984 • 327 citations

Long-term culture and fine specificity of human cytotoxic T-lymphocyte clones reactive with human immunodeficiency virus type 1.

1989 • 241 citations

Identification of levels of maternal HIV-1 RNA associated with risk of perinatal transmission: effect of maternal zidovudine treatment on viral load

1996 • 238 citations

Presence of maternal antibodies to human immunodeficiency virus 1 envelope glycoprotein gp120 epitopes correlates with the uninfected status of children born to seropositive mothers.

1989 • 226 citations

HIV in pregnant women and their offspring: evidence for late transmission

1991 • 220 citations

Vertical transmission of human immunodeficiency virus is correlated with the absence of high-affinity/avidity maternal antibodies to the gp120 principal neutralizing domain.

1990 • 216 citations

Maternal HIV-1 viral load and vertical transmission of infection: The Ariel Project for the prevention of HIV transmission from mother to infant

1997 • 204 citations

Mother-to-Child Transmission of the Human Immunodeficiency Virus

1995 • 198 citations

Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains

1997 • 192 citations

HIV-1 gag-specific cytotoxic T lymphocytes recognize multiple highly conserved epitopes. Fine specificity of the gag-specific response defined by using unstimulated peripheral blood mononuclear cells and cloned effector cells.

1991 • 191 citations

Patterns of Immunodominance in HIV-1–specific Cytotoxic T Lymphocyte Responses in Two Human Histocompatibility Leukocyte Antigens (HLA)-identical Siblings with HLA-A*0201 Are Influenced by Epitope Mutation

1997 • 187 citations

Comparison of variable region 3 sequences of human immunodeficiency virus type 1 from infected children with the RNA and DNA sequences of the virus populations of their mothers.

1993 • 181 citations

Maternal plasma human immunodeficiency virus type 1 RNA level: a determinant and projected threshold for mother-to-child transmission.

1995 • 177 citations

Human immunodeficiency virus type 1 genetic evolution in children with different rates of development of disease

1997 • 163 citations

Refocusing neutralizing antibody response by targeted dampening of an immunodominant epitope.

1997 • 144 citations

Identification of Levels of Maternal HIV-1 RNA Associated With Risk of Perinatal Transmission

1996 • 139 citations

Maintaining the integrity of human immunodeficiency virus sequence databases

1996 • 132 citations

Multiple aligned sequence editor (MASE)

1988 • 125 citations

Cellular immune factors associated with mother-to-infant transmission of HIV

1993 • 115 citations

Bi-specific monoclonal antibodies: selective binding and complement fixation to cells that express two different surface antigens.

1987 • 114 citations

Recognition of a highly conserved region of human immunodeficiency virus type 1 gp120 by an HLA-Cw4-restricted cytotoxic T-lymphocyte clone

1993 • 112 citations

Endogenous peptides bound to HLA-A3 possess a specific combination of anchor residues that permit identification of potential antigenic peptides.

1993 • 110 citations

Quantitation of human immunodeficiency virus type 1 during pregnancy: relationship of viral titer to mother-to-child transmission and stability of viral load.

1994 • 106 citations

Lack of Viral Escape and Defective In Vivo Activation of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Lymphocytes in Rapidly Progressive Infection

1999 • 94 citations

Early Viremia and Immune Responses in Vertical Human Immunodeficiency Virus Type 1 Infection

1993 • 80 citations

Vertical HIV-1 Transmission Correlates with a High Maternal Viral Load at Delivery

1997 • 72 citations

Perinatal HIV-1 transmission: recent advances and therapeutic interventions.

1996 • 71 citations

Overlapping epitopes in human immunodeficiency virus type 1 gp120 presented by HLA A, B, and C molecules: effects of viral variation on cytotoxic T-lymphocyte recognition

1997 • 66 citations

Mutations in human immunodeficiency virus type 1 gp41 affect sensitivity to neutralization by gp120 antibodies

1993 • 64 citations

Interaction between timing of perinatal human immunodeficiency virus infection and the design of preventive and therapeutic interventions

1997 • 61 citations

Vertical Transmission of HIV-1. Correlation with maternal viral load and plasma levels of CD4 binding site anti-gp120 antibodies.

1995 • 61 citations

T cell receptor usage and fine specificity of human immunodeficiency virus 1-specific cytotoxic T lymphocyte clones: analysis of quasispecies recognition reveals a dominant response directed against a minor in vivo variant.

1996 • 60 citations

Similarity in env and gag genes between genomic RNAs of human immunodeficiency virus type 1 (HIV-1) from mother and infant is unrelated to time of HIV-1 RNA positivity in the child

1995 • 60 citations

Vertical transmission of human immunodeficiency virus type 1: Autologous neutralizing antibody, virus load, and virus phenotype

1995 • 54 citations

Maternal Antibodies to gp120 V3 Sequence Do Not Correlate with Protection against Vertical Transmission of Human Immunodeficiency Virus

1992 • 48 citations