Single-Center Experience With Pimary Orthotopic Liver Transplation with FK 506 Immunosuppression

The mechanism of action of cyclosporin A and FK506

1992 • 2,127 citations

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1991 • 1,479 citations

A receptor for the immuno-suppressant FK506 is a cis–trans peptidyl-prolyl isomerase

1989 • 1,376 citations

CYCLOSPORIN A INITIALLY AS THE ONLY IMMUNOSUPPRESSANT IN 34 RECIPIENTS OF CADAVERIC ORGANS: 32 KIDNEYS, 2 PANCREASES, AND 2 LIVERS

1979 • 1,078 citations

Cell migration, chimerism, and graft acceptance

1992 • 1,075 citations

FK 506 FOR LIVER, KIDNEY, AND PANCREAS TRANSPLANTATION

1989 • 1,043 citations

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

1989 • 1,010 citations

Evolution of Liver Transplantation

1982 • 873 citations

Cell migration and chimerism after whole-organ transplantation: The basis of graft acceptance

1993 • 795 citations

Cyclosporin A, FK-506, and Rapamycin: Pharmacologic Probes of Lymphocyte Signal Transduction

1992 • 675 citations

The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes.

1989 • 667 citations

Liver Transplantation with Use of Cyclosporin a and Prednisone

1981 • 485 citations

THE REVERSAL OF REJECTION IN HUMAN RENAL HOMOGRAFTS WITH SUBSEQUENT DEVELOPMENT OF HOMOGRAFT TOLERANCE.

1963 • 389 citations

Bone marrow augmentation of donor-cell chimerism in kidney, liver, heart, and pancreas islet transplantation

1994 • 309 citations

Liver Transplantation

1989 • 300 citations

Liver, Kidney, and Thoracic Organ Transplantation Under FK 506

1990 • 252 citations

Donor cell chimerism permitted by immunosuppressive drugs: a new view of organ transplantation

1993 • 251 citations

HEPATIC ARTERY THROMBOSIS AFTER PEDIATRIC LIVER TRANSPLANTATION—A MEDICAL OR SURGICAL EVENT?1

1989 • 239 citations

Kidney Transplantation Under FK 506

1990 • 236 citations

Leukocyte chemotactic activity of cyclophilin.

1992 • 203 citations

STUDIES OF THE INDUCTION AND MAINTENANCE OF LONG-TERM GRAFT ACCEPTANCE BY TREATMENT WITH FK506 IN HETEROTOPIC CARDIAC ALLOTRANSPLANTATION IN RATS

1987 • 169 citations

FK 506 for human liver, kidney, and pancreas transplantation

1989 • 168 citations

An immunophilin that binds M(r) 90,000 heat shock protein: main structural features of a mammalian p59 protein.

1992 • 168 citations

Immunosuppression of canine, monkey, and baboon allografts by FK 506: with special reference to synergism with other drugs and to tolerance induction.

1988 • 160 citations

A highly sensitive method to assay FK-506 levels in plasma.

1987 • 149 citations

STUDIES OF THE EFFECTS OF FK506 ON RENAL ALLOGRAFTING IN THE BEAGLE DOG

1987 • 137 citations

Effect of a new immunosuppressive agent, FK 506, on heterotopic cardiac allotransplantation in the rat.

1987 • 136 citations

THE ADVERSE IMPACT ON LIVER TRANSPLANTATION OF USING POSITIVE CYTOTOXIC CROSSMATCH DONORS 1, 2

1992 • 125 citations

Randomized trial in primary liver transplantation under immunosuppression with FK 506 or cyclosporine.

1993 • 115 citations

THE EFFECT OF GRAFT FUNCTION ON FK506 PLASMA LEVELS, DOSAGES, AND RENAL FUNCTION, WITH PARTICULAR REFERENCE TO THE LIVER

1991 • 114 citations

AUGMENTATION OF RAT LIVER REGENERATION BY FK 506 COMPARED WITH CYCLOSPORIN

1989 • 97 citations

Immunosuppressive effect of FK-506 on in vitro lymphocyte alloactivation: synergism with cyclosporine A.

1987 • 94 citations

Conversion of liver allograft recipients from cyclosporine to FK 506-based immunosuppression: benefits and pitfalls.

1991 • 87 citations

Heterotopic heart transplantation in the rat receiving FK-506 alone or with cyclosporine.

1987 • 71 citations

LIVER TRANSPLANTATION IN POSITIVE CYTOTOXIC CROSSMATCH CASES USING FK506, HIGH-DOSE STEROIDS, AND PROSTAGLANDIN E

1992 • 68 citations

Renal transplantation in baboons under FK 506.

1990 • 64 citations

Cell migration and chimerism after whole-organ transplantation: The basis of graft acceptance

1993 • 63 citations

Selected topics on FK 506, with special references to rescue of extrahepatic whole organ grafts, transplantation of "forbidden organs," side effects, mechanisms, and practical pharmacokinetics.

1991 • 60 citations

EFFECTS OF COMBINATION TREATMENT WITH FK506 AND CYCLOSPORINE ON SURVIVAL TIME AND VASCULAR CHANGES IN RENAL-ALLOGRAFT-RECIPIENT DOGS

1989 • 57 citations

Canine kidney transplantation with FK-506 alone or in combination with cyclosporine and steroids.

1987 • 56 citations

Portal and arterial thrombosis in liver transplantation: a frequent event in severe rejection.

1989 • 55 citations

Pathological studies in canine and baboon renal allograft recipients immunosuppressed with FK-506.

1987 • 49 citations

Immunophilin-ligand complexes as probes of intracellular signaling pathways.

1991 • 46 citations

Kidney transplantation in the dog receiving FK-506.

1987 • 39 citations

Immunosuppressive drugs : developments in anti-rejection therapy

1994 • 37 citations

FK506

1988 • 32 citations

Randomized trial of FK 506/prednisone vs FK 506/azathioprine/prednisone after renal transplantation: preliminary report.

1993 • 27 citations

Heterotopic heart transplantation in the rat receiving FK-506.

1987 • 20 citations

Histopathologic studies in renal transplant recipient dogs receiving treatment with FK-506.

1987 • 19 citations

Renal transplantation in baboons under FK 506

1990 • 18 citations

OPTIMAL SERUM TROUGH LEVELS OF FK506 IN RENAL ALLOTRANSPLANTATION OF THE BEAGLE DOG

1989 • 17 citations

Contempo 89: Transplantation

1989 • 10 citations

Transplantation.

1989 • 6 citations