[32] Thimet oligopeptidase and oligopeptidase M or neurolysin

Tissue fractionation studies. 18. Resolution of mitochondrial fractions from rat liver into three distinct populations of cytoplasmic particles by means of density equilibration in various gradients

1964 • 346 citations

A soluble metalloendopeptidase from rat brain

1983 • 270 citations

Protein sorting in mitochondria

1992 • 174 citations

Membrane-bound kidney neutral metalloendopeptidase: interaction with synthetic substrates, natural peptides, and inhibitors

1983 • 170 citations

Synaptosomal Membrane‐Bound Form of Endopeptidase‐24.15 Generates Leu‐Enkephalin from Dynorphin _1‐8, α‐ and β‐Neoendorphin, and Met‐Enkephalin from Met‐Enkephalin‐Arg⁶‐Gly⁷‐Leu

1987 • 125 citations

Preparation, assay, and partial characterization of a neutral endopeptidase from rabbit brain

1973 • 119 citations

Endopeptidase 24.15 from rat testes. Isolation of the enzyme and its specificity toward synthetic and natural peptides, including enkephalin-containing peptides

1989 • 117 citations

Substrate-related potent inhibitors of brain metalloendopeptidase

1988 • 111 citations

Active site directed N-carboxymethyl peptide inhibitors of a soluble metalloendopeptidase from rat brain

1984 • 81 citations

A new and highly sensitive fluorescence assay for collagenase-like peptidase activity

1979 • 73 citations

Susceptibility of a peptide derived from bradykinin to hydrolysis by brain endo-oligopeptidases and pancreatic proteinases.

1979 • 71 citations

Characterization of a Mitochondrial Metallopeptidase Reveals Neurolysin as a Homologue of Thimet Oligopeptidase

1995 • 67 citations

PZ-peptidase from chick embryos. Purification, properties, and action on collagen peptides.

1977 • 67 citations

Human thimet oligopeptidase

1993 • 64 citations

ATP-dependent protease in bovine adrenal cortex. Tissue specificity, subcellular localization, and partial characterization.

1985 • 58 citations

Inhibition of endopeptidase 24.15 slows the in vivo degradation of luteinizing hormone-releasing hormone.

1989 • 58 citations

Immunocytochemical localization of endopeptidase 24.15 in rat brain

1992 • 57 citations

Proteinase yscD (oligopeptidase yscD)

1994 • 57 citations

Molecular cloning of porcine soluble angiotensin-binding protein.

1992 • 53 citations

Chicken liver Pz-peptidase, a thiol-dependent metallo-endopeptidase

1990 • 52 citations

Identification of a metalloprotease from Alzheimer's disease brain able to degrade the .beta.-amyloid precursor protein and generate amyloidogenic fragments

1994 • 48 citations

An alternative quenched fluorescence substrate for Pz-peptidase

1990 • 47 citations

An Inhibitor of Endopeptidase‐24.15 Blocks the Degradation of Intraventricularly Administered Dynorphins

1990 • 45 citations

Thimet oligopeptidase: similarity to ‘soluble angiotensin II-binding protein’ and some corrections to the published amino acid sequence of the rat testis enzyme

1993 • 43 citations

A selective assay for endooligopeptidase a based on the cleavage of fluorogenic substrate structurally related to enkephalin

1990 • 39 citations

Human brain peptidase activity with the specificity to generate the N-terminus of the Alzheimer β-amyloid protein from its precursor

1992 • 37 citations

Localization of Endo‐Oligopeptidase (EC 3.4.22.19) in the Rat Nervous Tissue

1990 • 37 citations

Thiol-dependent metallo-endopeptidase characteristics of Pz-peptidase in rat and rabbit

1990 • 35 citations

Rabbit liver microsomal endopeptidase with substrate specificity for processing proproteins is structurally related to rat testes metalloendopeptidase 24.15

1993 • 34 citations

A microsomal endopeptidase from liver with substrate specificity for processing proproteins such as the vitamin K-dependent proteins of plasma.

1992 • 33 citations

A continuous fluorimetric assay for clostridial collagenase and Pz-peptidase activity

1989 • 33 citations

Cloning, amino acid sequence and tissue distribution of porcine thimet oligopeptidase

1994 • 32 citations

Secretion of a Neuropeptide-Metabolizing Enzyme Similar to Endopeptidase 22.19 by Glioma C6-Cells

1993 • 32 citations

REVIEW

1993 • 31 citations

Fluorimetric assay of the neurotensin-degrading metalloendopeptidase, endopeptidase 24.16

1991 • 30 citations

The activities of ‘Pz-peptidase’ and ‘endopeptidase 24.15’ are due to a single enzyme

1989 • 29 citations

Potent inhibition of endopeptidase 24.16 and endopeptidase 24.15 by the phosphonamide peptide N-(phenylethylphosphonyl)-Gly-<scp>l</scp>-Pro-<scp>l</scp>-aminohexanoic acid

1992 • 28 citations

Endopeptidase-24.15 in rat hypothalamic/pituitary/gonadal axis

1991 • 26 citations

Isolation and Characterization of Gastric Trypsin from the Microsomal Fraction of Porcine Gastric Antral Mucosa

1995 • 25 citations

The Use of Synthetic Substrates for the Determination of Mammalian Collagenases. Is Collagenolytic Activity present in Mitochondria?

1969 • 25 citations

Structural requirements of bioactive peptides for interaction with endopeptidase 22.19

1994 • 23 citations

Endopeptidase 3.4.24.11 converts N-1-(R,S)carboxy-3-phenylpropyl-Ala-Ala-Phe-p-carboxyanilide into a potent inhibitor of angiotensin-converting enzyme

1993 • 23 citations

Immunohistochemical Localization of Endopeptidase 24.15 in Rat Trachea, Lung Tissue, and Alveolar Macrophages

1990 • 23 citations

Evidence that enzymatic conversion of N-[1(R,S)-carboxy-3-phenylpropyl]-Ala-Ala-Phe-p-aminobenzoate, a specific inhibitor of endopeptidase 24.15, to N-[1 (R,S)-carboxy-3-phenylpropyl]-Ala-Ala is necessary for inhibition of angiotensin converting enzyme

1993 • 22 citations

Endooligopeptidase A activity in rabbit heart: Generation of enkephalin from enkephalin containing peptides

1988 • 22 citations

Activity of Pz-peptidase and endo-oligopeptidase are due to the same enzyme

1989 • 21 citations

A distinct thimet peptidase from rat liver mitochondria

1990 • 21 citations

Endothelin mobilizes calcium and enhances glucose uptake in cultured human skeletal myoblasts and L6 myotubes.

1994 • 19 citations

Partial Purification and Characterization of Gelatinase and Metal Dependent Peptidase from Rabbit Uterus and Their Synergistic Action on Gelatin In Vitro

1983 • 17 citations

Modulatory effect of endopeptidase inhibitors on bradykinin-induced contraction of rat uterus.

1993 • 17 citations

Dynorphin-Derived Peptides Reveal the Presence of a Critical Cysteine for the Activity of Brain Endo-oligopeptidase A

1993 • 16 citations

Structure/function relationships in the inhibition of thimet oligopeptidase by carboxyphenylpropyl‐peptides

1991 • 13 citations

Rise in serum levels of PZ-peptidase, an enzyme involved in collagen breakdown, in human pregnancy and labor

1984 • 12 citations

Immunolocalization of Thimet Oligopeptidase in Chicken Embryonic Fibroblasts

1995 • 11 citations

Distribution of endopeptidase-24.15 in rat brain nuclei using a novel fluorogenic substrate: Comparison with endopeptidase-24.11

1991 • 10 citations

Highly sensitive assay for PZ-peptidase activity by high-performance liquid chromatography

1985 • 9 citations

Peptide inhibitors of E. collagenolyticum bacterial collagenase ‐effect of N‐methylation

1992 • 9 citations

Soluble Angiotensin II-Binding Protein

1991 • 8 citations

Presence of endo-oligopeptidase (EC 3.4.22.19), a putative neuropeptide-metabolizing endopeptidase in cells of the immune system

1992 • 8 citations

Isolation of a neurotensin-degrading enzyme from rat brain

1984 • 6 citations

Amino Acids and Peptides. XXXVI. Synthesis of Enkephalin Chloromethyl Ketone and Evaluation of Its Inhibitory Activity against Endopeptidase 22.19.

1993 • 5 citations

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