Endopeptidase 3.4.24.11 converts N-1-(R,S)carboxy-3-phenylpropyl-Ala-Ala-Phe-p-carboxyanilide into a potent inhibitor of angiotensin-converting enzyme
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Abstract
References (16)
A new class of angiotensin-converting enzyme inhibitors
1980 • 704 citations
A continuous spectrophotometric assay for angiotensin converting enzyme
1979 • 416 citations
A soluble metalloendopeptidase from rat brain
1983 • 270 citations
Neuropeptides and their peptidases
1988 • 204 citations
Purification and characterization of a novel neurotensin-degrading peptidase from rat brain synaptic membranes.
1986 • 139 citations
Synaptosomal Membrane‐Bound Form of Endopeptidase‐24.15 Generates Leu‐Enkephalin from Dynorphin 1‐8, α‐ and β‐Neoendorphin, and Met‐Enkephalin from Met‐Enkephalin‐Arg6‐Gly7‐Leu
1987 • 125 citations
Endopeptidase 24.15 from rat testes. Isolation of the enzyme and its specificity toward synthetic and natural peptides, including enkephalin-containing peptides
1989 • 117 citations
Substrate-related potent inhibitors of brain metalloendopeptidase
1988 • 111 citations
Purification of a membrane-bound metalloendopeptidase from porcine kidney that degrades peptide hormones.
1981 • 95 citations
The Design and Properties of N‐Carboxyalkyldipeptide Inhibitors of Angiotensin‐Converting Enzyme
1985 • 95 citations
Inactivation of Neurotensin by Rat Brain Synaptic Membranes Partly Occurs Through Cleavage at the Arg8‐Arg9 Peptide Bond by a Metalloendopeptidase
1985 • 81 citations
Purification and properties of a neurotensin-degrading endopeptidase from pig brain
1991 • 38 citations
Inhibition of endopeptidase-24.15 decreases blood pressure in normotensive rats.
1991 • 38 citations
Peripheral inactivation of neurotensin
1988 • 36 citations
Thiol-dependent metallo-endopeptidase characteristics of Pz-peptidase in rat and rabbit
1990 • 35 citations
Inhibition of angiotensin converting enzyme by the metalloendopeptidase 3.4.24.15 inhibitor c-phenylpropyl-alanyl-alanyl-phenylalanyl-p-aminobenzoate
1992 • 21 citations