Structural features of liver microsomal NADPH-cytochrome P-450 reductase. Hydrophobic domain, hydrophilic domain, and connecting region.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

Hepatic Triphosphopyridine Nucleotide-Cytochrome c Reductase: Isolation, Characterization, and Kinetic Studies

1962 • 1,431 citations

The Solubility of Amino Acids and Two Glycine Peptides in Aqueous Ethanol and Dioxane Solutions

1971 • 1,417 citations

Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatography.

1976 • 1,180 citations

Flavins and Flavoproteins

1977 • 826 citations

Role of Hemoprotein P-450 in Fatty Acid ω-Hydroxylation in a Soluble Enzyme System from Liver Microsomes

1968 • 625 citations

Resolution of the Cytochrome P-450-containing ω-Hydroxylation System of Liver Microsomes into Three Components

1969 • 573 citations

Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450

1976 • 536 citations

Purification and Properties of an Extracellular Protease of Staphylococcus aureus

1972 • 504 citations

Microsomes, Drug Oxidations and Chemical Carcinogenesis

1980 • 498 citations

Microsomes and Drug Oxidations

1970 • 463 citations

Phosphatidylcholine Requirement in the Enzymatic Reduction of Hemoprotein P-450 and in Fatty Acid, Hydrocarbon, and Drug Hydroxylation

1970 • 462 citations

Polyquarternary amines prevent peptide loss from sequenators

1978 • 452 citations

Application of 0.1 M quadrol to the microsequence of proteins and the sequence of tryptic peptides

1975 • 397 citations

A new convenient method for estimation of total cystine-cysteine in proteins

1969 • 346 citations

Purified liver microsomal NADPH-cytochrome P-450 reductase. Spectral characterization of oxidation-reduction states.

1978 • 346 citations

Properties of hepatic reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase

1973 • 344 citations

An examination of conditions for the cleavage of polypeptide chains with cyanogen bromide: Application to catalase

1969 • 287 citations

A technique for the removal of pyroglutamic acid from the amino terminus of proteins using calf liver pyroglutamate amino peptidase

1978 • 253 citations

Identification of the high and low potential flavins of liver microsomal NADPH-cytochrome P-450 reductase.

1978 • 238 citations

[34] Improved manual sequencing methods

1977 • 228 citations

Interactions of cytochrome P-450, NADPH-cytochrome P-450 reductase, phospholipid, and substrate in the reconstituted liver microsomal enzyme system.

1980 • 224 citations

Mitochondria and Microsomes

1982 • 223 citations

NADPH-cytochrome P-450 reductase from rat liver: purification by affinity chromatography and characterization

1977 • 205 citations

Cytochrome b5 reduction by NADPH-cytochrome P-450 reductase.

1979 • 199 citations

On the Hydrophobic Nature of Signal Sequences

1981 • 193 citations

Properties of NADPH-cytochrome P-450 reductase purified from rabbit liver microsomes

1979 • 181 citations

Highly purified detergent-solubilized NADPH-cytochrome P-450 reductase from phenobarbital-induced rat liver microsomes

1974 • 171 citations

Partial primary structure of bacteriorhodopsin: sequencing methods for membrane proteins.

1979 • 170 citations

Cytochrome P-450 purified to apparent homogeneity from phenobarbital-induced rabbit liver microsomes: Catalytic activity and other properties

1974 • 164 citations

Amino acid compositions and partial amino acid sequences of three highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, or 3-methylcholanthrene.

1979 • 153 citations

Studies on the association of cytochrome P-450 and NADPH-cytochrome c reductase during catalysis in a reconstituted hydroxylating system.

1979 • 135 citations

[28] Cleavage at aspartic acid

1967 • 134 citations

Hypothalamic Releasing Factors

1970 • 126 citations

Cytochrome b₅ from microsomal membranes of equine, bovine, and porcine livers. Isolation and properties of preparations containing the membranous segment

1974 • 117 citations

Role of a hydrophobic polypeptide in the N-terminal region of NADPH-cytochrome P-450 reductase in complex formation with P-450lm

1979 • 113 citations

Amino-terminal sequence of phenobarbital-inducible cytochrome P-450 from rabbit liver microsomes: Similarity to hydrophobic amino-terminal segments of preproteins

1977 • 104 citations

NADPH-cytochrome P-450 reductase of yeast microsomes

1978 • 83 citations

Micro method for detection of formyl and acetyl groups in proteins

1969 • 80 citations

Purified NADPH cytochrome P-450 reductase. Interaction with hepatic microsomes and phospholipid vesicles.

1979 • 77 citations

Detergent-solubilized NADPH-cytochrome c(P-450) reductase from the higher plant, Catharanthus roseus. Purification and characterization

1979 • 75 citations

The history, properties, and function of NADPH-cytochrome P-450 reductase

1980 • 72 citations

Orientation of the carboxyl and NH2 termini of the membrane-binding segment of cytochrome b5 on the same side of phospholipid bilayers.

1981 • 63 citations

Preparation of homogenous NADPH cytochrome c (P-450) reductase from house flies using affinity chromatography techniques.

1979 • 62 citations

Isolation of the membrane-binding peptide of NADPH-cytochrome P-450 reductase. Characterization of the peptide and its role in the interaction of reductase with cytochrome P-450.

1981 • 56 citations

A COMPUTER‐ASSISTED METHOD FOR DETERMINING THE NEAREST INTEGER RATIOS OF AMINO ACID RESIDUES IN PURIFIED PROTEINS

1974 • 52 citations

Reduced nicotinamide adenine dinucleotide-cytochrome b5 reductase: location of the hydrophobic, membrane-binding region at the carboxyl-terminal end and the masked amino terminus

1978 • 44 citations

Interaction between NADPH-cytochrome P-450 reductase and hepatic microsomes

1978 • 38 citations

Hepatic microsomal epoxide hydrase. Chemical evidence for a single polypeptide chain.

1979 • 37 citations

Purification and properties of cytochrome P-450 and NADPH-cytochrome c (P-450) reductase from human liver microsomes

1979 • 32 citations

The primary structure of the alpha subunit of protocatechuate 3,4-dioxygenase. I. Isolation and sequence of the tryptic peptides.

1979 • 32 citations

The prediction of the conformation of membrane proteins from the sequence of amino acids

1976 • 28 citations

Calibration mixture for estimation of peptide molecular weight by exclusion chromatography

1979 • 8 citations