Hepatic microsomal epoxide hydrase. Chemical evidence for a single polypeptide chain.

Arene Oxides: A New Aspect of Drug Metabolism

1974 • 1,043 citations

Epoxides in Polycyclic Aromatic Hydrocarbon Metabolism and Carcinogenesis

1974 • 739 citations

Quantitative procedures for use with the Edman-Begg sequenator. Partial sequences of two unusual immunoglobulin light chains, Rzf and Sac

1971 • 679 citations

Rapid analysis of amino acid phenylthiohydantoins by high-performance liquid chromatography

1977 • 645 citations

Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450

1976 • 536 citations

Cell-free synthesis of rat preproinsulins: characterization and partial amino acid sequence determination.

1976 • 279 citations

Mutagenicity and cytotoxicity of benzo(a)pyrene benzo-ring epoxides.

1976 • 232 citations

The resolution and reconstitution of the liver microsomal hydroxylation system

1974 • 223 citations

Metabolism of benzo[a]pyrene: conversion of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to highly mutagenic 7,8-diol-9,10-epoxides.

1976 • 206 citations

Liver microsomal expoxide hydrase. Solubilization, purification, and characterization.

1975 • 170 citations

Amino acid compositions and partial amino acid sequences of three highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, or 3-methylcholanthrene.

1979 • 153 citations

Purification of rat liver epoxide hydratase to apparent homogeneity

1975 • 126 citations

Gas chromatography of neutral and amino sugars in glycoproteins

1971 • 123 citations

Pre-proparathyroid hormone: Analysis of radioactive tryptic peptides and amino acid sequence

1976 • 120 citations

Amino-terminal sequence of phenobarbital-inducible cytochrome P-450 from rabbit liver microsomes: Similarity to hydrophobic amino-terminal segments of preproteins

1977 • 104 citations

Substrate specificity of hepatic epoxide hydrase in microsomes and in a purified preparation: Evidence for homologous enzymes

1971 • 100 citations

Liver microsomal epoxide hydrase.

1977 • 99 citations

ADVANCES IN PHARMACOLOGY AND THERAPEUTICS

1979 • 85 citations

Epoxides Derived from Various Polycyclic Hydrocarbons as Substrates of Homogeneous and Microsome‐Bound Epoxide Hydratase

1976 • 82 citations

Hepatic microsomal epoxide hydrase. Involvement of a histidine at the active site suggests a nucleophilic mechanism.

1978 • 80 citations

Amino acid sequence of the NH2-terminal extra piece segments of the precursors of mouse immunoglobulin lambda1-type and kappa-type light chains.

1977 • 80 citations

Partial amino acid sequence of human placental lactogen precursor and its mature hormone form produced by membrane-associated enzyme activity

1977 • 76 citations

Tumorigenicity of five dihydrodiols of benz(a)anthracene on mouse skin: exceptional activity of benz(a)anthracene 3,4-dihydrodiol.

1977 • 66 citations

Antibodies against homogeneous epoxide hydratase provide evidence for a single enzyme hydrating styrene oxide and benz(a)pyrene 4,5-oxide

1976 • 57 citations

A simple method for purification of epoxide hydratase from rat liver

1977 • 55 citations

Liver microsomal epoxide hydrase: activation, inhibition, and immunological properties of the purified enzyme.

1978 • 49 citations

Properties and amino acid composition of pure epoxide hydratase

1975 • 45 citations

Assay and partial purification of epoxide hydrase from rat liver microsomes

1974 • 40 citations

Automated sequencing of insoluble peptides using detergent. Bacteriophage fl coat protein.

1977 • 32 citations