Defects in TCIRG1 subunit of the vacuolar proton pump are responsible for a subset of human autosomal recessive osteopetrosis

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

1999 • 3,340 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice

1998 • 900 citations

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

1995 • 875 citations

Osteoclastic Bone Resorption by a Polarized Vacuolar Proton Pump

1989 • 864 citations

Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border.

1985 • 738 citations

The cell biology of osteoclast function

2000 • 694 citations

Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification

1999 • 462 citations

Partial V(D)J Recombination Activity Leads to Omenn Syndrome

1998 • 459 citations

Structure and Properties of the Vacuolar (H+)-ATPases

1999 • 308 citations

Autosomal Recessive Osteopetrosis: Variability of Findings at Diagnosis and During the Natural Course

1994 • 214 citations

The gene encoding the mouse homologue of the human osteoclast-specific 116-kDa V-ATPase subunit bears a deletion in osteosclerotic (oc/oc) mutants

2000 • 199 citations

Osteopetrosis and osteoporosis:two sides of the same coin

1999 • 118 citations

Molecular Cloning and Characterization of a Putative Novel Human Osteoclast-Specific 116-kDa Vacuolar Proton Pump Subunit

1996 • 98 citations

Human autosomal recessive osteopetrosis maps to 11q13, a position predicted by comparative mapping of the murine osteosclerosis (oc) mutation

1998 • 91 citations

Prevention of Acute Allograft Rejection by Antibody Targeting of TIRC7, a Novel T Cell Membrane Protein

1998 • 69 citations

Genomic Organization of the Gene Coding for TIRC7, a Novel Membrane Protein Essential for T Cell Activation

1999 • 63 citations

Osteosclerosis, a recessive skeletal mutation on chromosome 19 in the mouse

1985 • 51 citations

Hematopoietic stem cell transplantation for infantile osteopetrosis

1998 • 36 citations