Immune regulation by brain cells in the central nervous system: microglia but not astrocytes present myelin basic protein to encephalitogenic T cells under in vivo-mimicking conditions.

Characterization of ameboid microglia isolated from developing mammalian brain

1986 • 1,287 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells.

1982 • 754 citations

Identification of Ia glycoproteins in rat thymus and purification from rat spleen

1979 • 682 citations

Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3.

1986 • 602 citations

Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation.

1985 • 440 citations

Mouse monoclonal antibodies against rat major histocompatibility antigens. Two Ia antigens and expression of Ia and class I antigens in rat thymus

1982 • 364 citations

Class II MHC-bearing keratinocytes induce antigen-specific unresponsiveness in hapten-specific Th1 clones.

1988 • 241 citations

Intrathecal application of interferon gamma. Progressive appearance of MHC antigens within the rat nervous system.

1990 • 240 citations

The distribution of Ia antigen in the lesions of rat acute experimental allergic encephalomyelitis

1986 • 214 citations

Immunohistochemical analysis of the rat central nervous system during experimental allergic encephalomyelitis, with special reference to Ia-positive cells with dendritic morphology.

1986 • 204 citations

The V-region disease hypothesis: evidence from autoimmune encephalomyelitis

1989 • 190 citations

Expression of Ia antigens by cultured astrocytes treated with gamma-interferon

1983 • 182 citations

Hyperinducibility of Ia antigen on astrocytes correlates with strain-specific susceptibility to experimental autoimmune encephalomyelitis.

1987 • 163 citations

Immune‐Mediated Encephalitis: On the Role of Antigen‐Presenting Cells in Brain Tissue

1987 • 155 citations

Immune function of the blood-brain barrier: incomplete presentation of protein (auto-)antigens by rat brain microvascular endothelium in vitro.

1990 • 140 citations

T Cell Receptors in Murine Autoimmune Diseases

1989 • 137 citations

Presentation of myelin basic protein by murine cerebral vascular endothelial cells.

1985 • 129 citations

The T-Cell Receptor Repertoire and Autoimmune Diseases

1989 • 124 citations

Organ-Resident, Nonlymphoid Cells Suppress Proliferation of Autoimmune T-Helper Lymphocytes

1987 • 118 citations

Interaction between myelin basic protein-sensitized T lymphocytes and murine cerebral vascular endothelial cells.

1986 • 117 citations

Antigen presentation in brain: MHC induction on brain endothelium and astrocytes compared.

1987 • 115 citations

In situ demonstration of proliferating cells in the rat central nervous system during experimental autoimmune encephalomyelitis. Evidence suggesting that most infiltrating T cells do not proliferate in the target organ.

1992 • 112 citations

In situ detection of class I and II major histocompatibility complex antigens in the rat central nervous system during experimental allergic encephalomyelitis

1986 • 86 citations

In situ Ia expression on brain cells in the rat: autoimmune encephalomyelitis-resistant strain (BN) and susceptible strain (Lewis) compared.

1989 • 32 citations

Analysis of the T cell repertoire for myelin basic protein in thymus‐grafted and other types of chimera: evidence that major histocompatibility complex molecules on accessory cells rather than T cell specificity mainly regulate susceptibility to autoimmune encephalomyelitis

1990 • 24 citations

Minor lymphocyte stimulating (Mls) gene products in mice influence their genetic resistance or susceptibility to induction of autoimmune encephalomyelitis

1990 • 12 citations

Hemorrhagic autoimmune encephalomyelitis induced by adoptive transfer of activated semiallogeneic spleen cells into irradiated rats.

1988 • 12 citations