Contribution of the TATA motif to Tat-mediated transcriptional activation of human immunodeficiency virus gene expression

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

Die Molekularbiologie der Tumorviren

1977 • 951 citations

Trans -Activator Gene of Human T-Lymphotropic Virus Type III (HTLV-III)

1985 • 872 citations

[71] Use of eukaryotic expression technology in the functional analysis of cloned genes

1987 • 834 citations

The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat

1985 • 825 citations

Trans -Acting Transcriptional Activation of the Long Terminal Repeat of Human T Lymphotropic Viruses in Infected Cells

1984 • 781 citations

Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism

1986 • 730 citations

HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA

1986 • 673 citations

Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein

1987 • 672 citations

A second post-transcriptional trans-activator gene required for HTLV-III replication

1986 • 639 citations

HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation

1989 • 577 citations

Location of the Trans -Activating Region on the Genome of Human T-Cell Lymphotropic Virus Type III

1985 • 558 citations

Transcriptional activation by Sp1 as directed through TATA or initiator: specific requirement for mammalian transcription factor IID.

1990 • 501 citations

The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization

1989 • 400 citations

Regulation of human immunodeficiency virus env expression by the rev gene product

1989 • 365 citations

The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation.

1991 • 360 citations

The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region

1989 • 359 citations

Structure, sequence, and position of the stem-loop in tar determine transcriptional elongation by tat through the HIV-1 long terminal repeat.

1989 • 357 citations

Post-transcriptional regulation accounts for the trans-activation of the human T-lymphotropic virus type III

1986 • 325 citations

Family of proteins that interact with TFIID and regulate promoter activity

1991 • 319 citations

Elevated levels of mRNA can account for the trans-activation of human immunodeficiency virus.

1986 • 303 citations

Definition of multiple, functionally distinct TATA elements, one of which is a target in the hsp70 promoter for E1A regulation

1988 • 292 citations

A constitutive promoter directs expression of the nerve growth factor receptor gene.

1988 • 280 citations

HIV-1 Tat protein trans-activates transcription in vitro

1990 • 277 citations

A discrete element 3' of human immunodeficiency virus 1 (HIV-1) and HIV-2 mRNA initiation sites mediates transcriptional activation by an HIV trans activator.

1988 • 270 citations

Functional roles for the TATA promoter and enhancers in basal and Tat-induced expression of the human immunodeficiency virus type 1 long terminal repeat

1992 • 254 citations

Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events.

1987 • 246 citations

Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat

1988 • 235 citations

A TATA box implicated in E1A transcriptional activation of a simple adenovirus 2 promoter

1987 • 227 citations

HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors.

1992 • 195 citations

Functional heterogeneity of mammalian TATA-box sequences revealed by interaction with a cell-specific enhancer

1990 • 193 citations

Functional characterization of the NF-kappa B p65 transcriptional activator and an alternatively spliced derivative.

1992 • 177 citations

HIV TAR: An RNA enhancer?

1989 • 175 citations

A rapid method for the construction of synthetic genes using the polymerase chain reaction.

1990 • 171 citations

Localization of DNA sequences necessary for transcription of the rabbit β-globin gene in vitro

1981 • 158 citations

The mammalian TFIID protein is present in two functionally distinct complexes.

1991 • 142 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Purification and Analysis of Transcription Factor ILA and Identification of Transcription Factor IIJ

1992 • 136 citations

Synergy between HIV-1 Tat and adenovirus E1A is principally due to stabilization of transcriptional elongation.

1990 • 114 citations

Regulation of HIV gene expression by RNA-protein interactions

1991 • 73 citations

A Constitutive Promoter Directs Expression of the Nerve Growth Factor Receptor Gene

1988 • 72 citations

Transcriptional Regulatory Sequences of the Housekeeping Gene for Human Triosephosphate Isomerase

1989 • 51 citations

Functional Characterization of the NF-κB p65 Transcriptional Activator and an Alternatively Spliced Derivative

1992 • 49 citations

Promoter of the adenovirus polypeptide IX gene: similarity to E1B and inactivation by substitution of the simian virus 40 TATA element

1991 • 19 citations