Activation of the phosphosignaling protein CheY. I. Analysis of the phosphorylated conformation by 19F NMR and protein engineering

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1977 • 2,631 citations

COMMUNICATION MODULES IN BACTERIAL SIGNALING PROTEINS

1992 • 1,449 citations

[6] Quantitation of protein

1990 • 1,401 citations

Molecular Switch for Signal Transduction: Structural Differences Between Active and Inactive Forms of Protooncogenic ras Proteins

1990 • 1,037 citations

Signal transduction in bacteria

1990 • 683 citations

The Nature of the Chemical Bond and the Structure of Molecules and Crystals

1941 • 613 citations

Crystal Structure of the Ribonuclease H Domain of HIV-1 Reverse Transcriptase

1991 • 566 citations

Phosphorylation of three proteins in the signaling pathway of bacterial chemotaxis

1988 • 550 citations

SIGNAL TRANSDUCTION PATHWAYS INVOLVING PROTEIN PHOSPHORYLATION IN PROKARYOTES

1991 • 512 citations

Phosphorylation of bacterial response regulator proteins by low molecular weight phospho-donors.

1992 • 475 citations

Three-dimensional structure of CheY, the response regulator of bacterial chemotaxis

1989 • 350 citations

Genetic and Crystallographic Studies of the 3′,5′-Exonucleolytic Site of DNA Polymerase I

1988 • 344 citations

Crystallographic analysis of ribulose 1,5-bisphosphate carboxylase from spinach at 2·4 Å resolution

1990 • 312 citations

Identification of the site of phosphorylation of the chemotaxis response regulator protein, CheY

1989 • 303 citations

Structural changes in glycogen phosphorylase induced by phosphorylation

1988 • 302 citations

Crystal structure of Escherichia coli CheY refined at 1.7-A resolution.

1991 • 293 citations

Conserved aspartate residues and phosphorylation in signal transduction by the chemotaxis protein CheY.

1990 • 268 citations

Crystal structure of Escherichia coli CheY refined at 1.7-A resolution

1991 • 259 citations

Regulation of an Enzyme by Phosphorylation at the Active Site

1990 • 246 citations

Structural details of ribonuclease H from Escherichia coli as refined to an atomic resolution

1992 • 228 citations

Roles of the highly conserved aspartate and lysine residues in the response regulator of bacterial chemotaxis

1991 • 215 citations

Reconstitution of the bacterial chemotaxis signal transduction system from purified components

1991 • 211 citations

Relation between structure and function of α/β–protejns

1980 • 194 citations

Bacterial Chemotaxis and the Molecular Logic of Intracellular Signal Transduction Networks

1991 • 193 citations

Sensory transduction in bacterial chemotaxis involves phosphotransfer between CHE proteins

1988 • 181 citations

The dynamics of protein phosphorylation in bacterial chemotaxis

1990 • 173 citations

Divalent metal ion binding to the CheY protein and its significance to phosphotransfer in bacterial chemotaxis

1990 • 168 citations

Correlation between phosphorylation of the chemotaxis protein CheY and its activity at the flagellar motor

1992 • 154 citations

Overexpression and sequence of the Escherichia coli cheY gene and biochemical activities of the CheY protein

1984 • 129 citations

Modulation of the Dimerization of a Transcriptional Antiterminator Protein by Phosphorylation

1992 • 129 citations

Crystal structure of fructose-1,6-bisphosphatase complexed with fructose 6-phosphate, AMP, and magnesium.

1990 • 112 citations

Signal transduction in bacterial chemotaxis.

1992 • 111 citations

Phosphorylase: a biological transducer

1992 • 109 citations

Fluorine nuclear magnetic resonance analysis of the ligand binding properties of two homologous rat cellular retinol-binding proteins expressed in Escherichia coli

1991 • 107 citations

Fluorine-19 NMR studies of the D-galactose chemosensory receptor. 1. Sugar binding yields a global structural change

1991 • 105 citations

Fluorotyrosine Alkaline Phosphatase from Escherichia coli : Preparation, Properties, and Fluorine-19 Nuclear Magnetic Resonance Spectrum

1974 • 105 citations

Mechanism of enolase: the crystal structure of enolase-magnesium-2-phosphoglycerate/phosphoenolpyruvate complex at 2.2-.ANG. resolution

1991 • 104 citations

Activation of the phosphosignaling protein CheY. II. Analysis of activated mutants by 19F NMR and protein engineering

1993 • 96 citations

A chemotactic signaling surface on CheY defined by suppressors of flagellar switch mutations

1992 • 93 citations

Regulation of isocitrate dehydrogenase by phosphorylation involves no long-range conformational change in the free enzyme.

1990 • 85 citations

Novel ion specificity of a carboxylate cluster magnesium(II) binding site: Strong charge selectivity and weak size selectivity

1993 • 77 citations

Crystal structure of the ternary complex of ribulose-1,5-bisphosphate carboxylase, magnesium(II) and activator carbon dioxide at 2.3-.ANG. resolution

1991 • 76 citations

The specific incorporation of labelled aromatic amino acids into proteins through growth of bacteria in the presence of glyphosate

1990 • 76 citations

Incorporation of fluorotryptophans into proteins of Escherichia coli

1975 • 75 citations

Regulation of isocitrate dehydrogenase by phosphorylation involves no long-range conformational change in the free enzyme.

1990 • 74 citations

[15] Phosphorylation assays for proteins of the two-component regulatory system controlling chemotaxis in Escherichia coli

1991 • 71 citations

The incorporation of p-fluorophenylalanine into some rabbit enzymes and other proteins

1961 • 66 citations

Open conformation of a substrate-binding cleft: fluorine-19 NMR studies of cleft angle in the D-galactose chemosensory receptor

1991 • 57 citations

Nuclear magnetic resonance and molecular genetic studies of the membrane-bound D-lactate dehydrogenase of Escherichia coli

1987 • 55 citations

Signal transduction and osmoregulation in Escherichia coli. A novel type of mutation in the phosphorylation domain of the activator protein, OmpR, results in a defect in its phosphorylation-dependent DNA binding

1991 • 53 citations

Nuclear magnetic resonance and fluorescence studies of substrate-induced conformational changes of histidine-binding protein J of Salmonella typhimurium

1977 • 49 citations

lac repressor: 3-fluorotyrosine substitution for nuclear magnetic resonance studies.

1976 • 46 citations

Membrane protein conformational change dependent on the hydrophobic environment

1985 • 41 citations

Prediction of fluorine chemical shifts in proteins

1991 • 40 citations

Protein Phosphorylation and the Regulation of Cellular Processes by the Homologous Two-Component Regulatory Systems of Bacteria

1991 • 38 citations

19F-n.m.r. studies of ligand binding to 5-fluorotryptophan- and 3-fluorotyrosine-containing cyclic AMP receptor protein from Escherichia coli

1990 • 34 citations

Magnetic resonance studies of protein-small molecule interactions. Binding of N-trifluoroacetyl-D-(and L-)-p-fluorophenylalanine to .alpha.-chymotrypsin

1972 • 34 citations

Fluorine-19 nuclear magnetic resonance study of 5-fluorotryptophan-labeled histidine-binding protein J of Salmonella typhimurium

1984 • 33 citations

Site-specific incorporation of 5-fluorotryptophan as a probe of the structure and function of the membrane-bound D-lactate dehydrogenase of Escherichia coli: a fluorine-19 nuclear magnetic resonance study

1990 • 28 citations

19F nuclear magnetic resonance studies of fluorotyrosine-labeled aspartate transcarbamoylase. Properties of the enzyme and its catalytic and regulatory subunits.

1985 • 23 citations

19F nuclear magnetic resonance studies of 6-fluorotryptophan-substituted rat cellular retinol binding protein II produced in Escherichia coli. An analysis of four tryptophan substitution mutants and their interactions with all-trans-retinol.

1990 • 23 citations

Fluorine-19 NMR studies of the D-galactose chemosensory receptor. 2. Calcium binding yields a local structural change

1991 • 22 citations

Bivalent-metal binding to CheY protein. Effect on protein conformation

1992 • 20 citations