Severe impairment of salivation in Na+/K+/2Cl- cotransporter (NKCC1)-deficient mice.

Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney

1994 • 591 citations

Xerostomia: evaluation of a symptom with increasing significance

1985 • 534 citations

Role of salivary mucins in the protection of the oral cavity

1982 • 522 citations

The role of saliva in maintaining oral homeostasis

1989 • 436 citations

Deafness and imbalance associated with inactivation of the secretory Na-K-2Cl co-transporter

1999 • 396 citations

Mice Lacking the Basolateral Na-K-2Cl Cotransporter Have Impaired Epithelial Chloride Secretion and Are Profoundly Deaf

1999 • 386 citations

Cloning and Characterization of KCC3 and KCC4, New Members of the Cation-Chloride Cotransporter Gene Family

1999 • 298 citations

Phenotype Resembling Gitelman's Syndrome in Mice Lacking the Apical Na+-Cl− Cotransporter of the Distal Convoluted Tubule

1998 • 291 citations

Mouse Down-regulated in Adenoma (DRA) Is an Intestinal Cl−/HCO3− Exchanger and Is Up-regulated in Colon of Mice Lacking the NHE3 Na+/H+Exchanger

1999 • 273 citations

Molecular cloning and chromosome localization of a putative basolateral Na(+)-K(+)-2Cl- cotransporter from mouse inner medullary collecting duct (mIMCD-3) cells.

1994 • 266 citations

Primary Structure, Functional Expression, and Chromosomal Localization of the Bumetanide-sensitive Na-K-Cl Cotransporter in Human Colon

1995 • 253 citations

Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion.

1998 • 249 citations

The Na-K-Cl cotransporters.

1998 • 237 citations

Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures

1999 • 230 citations

Cystic Fibrosis Transmembrane Conductance Regulator Regulates Luminal Cl−/HCO3−Exchange in Mouse Submandibular and Pancreatic Ducts

1999 • 196 citations

Polarized distribution of key membrane transport proteins in the rat submandibular gland

1996 • 170 citations

Activation of calcium-dependent chloride channels in rat parotid acinar cells.

1996 • 154 citations

[Ca2+]i modulation of Cl- content controls cell volume in single salivary acinar cells during fluid secretion

1990 • 151 citations

Molecular Cloning, Expression Pattern, and Chromosomal Localization of the Human Na–Cl Thiazide-Sensitive Cotransporter (SLC12A3)

1996 • 128 citations

All Three WW Domains of Murine Nedd4 Are Involved in the Regulation of Epithelial Sodium Channels by Intracellular Na+

1999 • 123 citations

The Electroneutral Cation–Chloride Cotransporters

1998 • 99 citations

Effects of Ca2+ and furosemide on Cl- transport and O2 uptake in rat parotid acini

1986 • 90 citations

The establishment of a xerostomia clinic: a prospective study

1997 • 90 citations

The anionic basis of fluid secretion by the rabbit mandibular salivary gland.

1984 • 87 citations

The role of HCO3- and Na+/H+ exchange in the response of rat parotid acinar cells to muscarinic stimulation.

1988 • 79 citations

Two independent anion transport systems in rabbit mandibular salivary glands

1986 • 77 citations

Membrane‐limited expression and regulation of Na⁺‐H⁺ exchanger isoforms by P₂ receptors in the rat submandibular gland duct

1998 • 72 citations

Beta-adrenergic upregulation of the Na(+)-K(+)-2Cl- cotransporter in rat parotid acinar cells.

1992 • 68 citations

Acetylcholine-induced intracellular acidosis in rabbit salivary gland acinar cells

1989 • 66 citations

Na+, K+, and H+/HCO3− Transport in Submandibular Salivary Ducts

1995 • 65 citations

A muscarinic agonist-stimulated chloride efflux pathway is associated with fluid secretion in rat parotid acinar cells

1987 • 63 citations

Targeted Disruption of the Nhe1 Gene Prevents Muscarinic Agonist-induced Up-regulation of Na+/H+ Exchange in Mouse Parotid Acinar Cells

1999 • 61 citations

Upregulation of Na(+)‐K(+)‐2Cl‐ cotransporter activity in rat parotid acinar cells by muscarinic stimulation.

1997 • 61 citations

Molecular and topological characterization of the rat parotid Na + -K + -2Cl − cotransporter 1The nucleotide sequence reported here has been submitted to the GenBank/European Molecular Biology Laboratory database under accession No. AF051561. 1

1998 • 57 citations

Characterization of a phosphorylation event resulting in upregulation of the salivary Na⁺-K⁺-2Cl⁻cotransporter

1999 • 55 citations

Salivary gland hypofunction in elderly patients attending a xerostomia clinic

1995 • 55 citations

Agonist-induced activation of Na+/H+ exchange in rat parotid acinar cells is dependent on calcium but not on protein kinase C.

1990 • 49 citations

Amiloride-sensitive Na+ current in the granular duct cells of mouse mandibular glands

1993 • 45 citations

Ion transport mechanisms in rat parotid intralobular striated ducts

1994 • 30 citations

The effects of bumetanide, amiloride and Ba2+ on fluid and electrolyte secretion in rabbit salivary gland.

1990 • 29 citations

Regulation of cytoplasmic pH in rat sublingual mucous acini at rest and during muscarinic stimulation

1992 • 29 citations

The ACh-evoked, Ca 2+ -activated Whole-cell K + Current in Mouse Mandibular Secretory Cells. Whole-cell and Fluorescence Studies

1996 • 20 citations

Bay K 8644 reveals two components of L-type Ca2+ channel current in clonal rat pituitary cells.

1996 • 19 citations

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