Repression of myogenin function by TGF-beta 1 is targeted at the basic helix-loop-helix motif and is independent of E2A products.

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

The protein Id: A negative regulator of helix-loop-helix DNA binding proteins

1990 • 2,273 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

The myoD Gene Family: Nodal Point During Specification of the Muscle Cell Lineage

1991 • 1,564 citations

Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD

1989 • 1,286 citations

Type beta transforming growth factor: a bifunctional regulator of cellular growth.

1985 • 1,107 citations

A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts.

1989 • 919 citations

Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

1991 • 874 citations

A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program.

1989 • 863 citations

MyoD1: A Nuclear Phosphoprotein Requiring a Myc Homology Region to Convert Fibroblasts to Myoblasts

1988 • 839 citations

The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

1990 • 794 citations

Identification of MRF4: a new member of the muscle regulatory factor gene family.

1989 • 779 citations

Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes.

1986 • 777 citations

MyoD family: a paradigm for development?

1990 • 776 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex.

1990 • 647 citations

A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-β

1988 • 620 citations

Type beta transforming growth factor is the primary differentiation-inducing serum factor for normal human bronchial epithelial cells.

1986 • 570 citations

Two Distinct Transcription Factors that Bind the Immunoglobulin Enhancer μE5/κE2 Motif

1990 • 478 citations

TGF-β1 inhibition of transin/stromelysin gene expression is mediated through a fos binding sequence

1990 • 444 citations

Inhibition of Endothelial Regeneration by Type-Beta Transforming Growth Factor from Platelets

1986 • 439 citations

Functional antagonism between c-Jun and MyoD proteins: A direct physical association

1992 • 424 citations

Hormones, Growth Factors, and Myogenic Differentiation

1991 • 399 citations

Type beta transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts.

1985 • 364 citations

Muscle-specific transcriptional activation by MyoD.

1991 • 347 citations

Identification of a myocyte nuclear factor that binds to the muscle-specific enhancer of the mouse muscle creatine kinase gene.

1989 • 326 citations

MyoD binds cooperatively to two sites in a target enhancer sequence: occupancy of two sites is required for activation.

1990 • 294 citations

Transformation by activated ras or fos prevents myogenesis by inhibiting expression of MyoD1

1989 • 286 citations

Myogenin resides in the nucleus and acquires high affinity for a conserved enhancer element on heterodimerization.

1990 • 278 citations

Promoter Sequences of the Human Transforming Growth Factor-β1 Gene Responsive to Transforming Growth Factor-β1 Autoinduction

1989 • 254 citations

Fos and Jun repress transcriptional activation by myogenin and MyoD: the amino terminus of Jun can mediate repression.

1992 • 250 citations

Identification of upstream and intragenic regulatory elements that confer cell-type-restricted and differentiation-specific expression on the muscle creatine kinase gene.

1988 • 248 citations

Transforming growth factor-beta. A very potent inhibitor of myoblast differentiation, identical to the differentiation inhibitor secreted by Buffalo rat liver cells.

1986 • 247 citations

Enhanced jun gene expression is an early genomic response to transforming growth factor beta stimulation.

1989 • 213 citations

Fibroblast Growth Factor and Transforming Growth Factor β Repress Transcription of the Myogenic Regulatory Gene MyoD1

1989 • 212 citations

Serum and fibroblast growth factor inhibit myogenic differentiation through a mechanism dependent on protein synthesis and independent of cell proliferation.

1986 • 196 citations

Transforming growth factor beta represses the actions of myogenin through a mechanism independent of DNA binding.

1991 • 167 citations

Differential trans activation associated with the muscle regulatory factors MyoD1, myogenin, and MRF4.

1990 • 157 citations

Transcriptional activation domain of the muscle-specific gene-regulatory protein myf5

1990 • 128 citations

The basic region of myogenin cooperates with two transcription activation domains to induce muscle-specific transcription.

1992 • 110 citations

Different members of the jun proto-oncogene family exhibit distinct patterns of expression in response to type beta transforming growth factor.

1990 • 91 citations

Differential trans-activation of a muscle-specific enhancer by myogenic helix-loop-helix proteins is separable from DNA binding.

1991 • 89 citations

Cell adhesion to collagen and decreased myogenic gene expression implicated in the control of myogenesis by transforming growth factor beta.

1990 • 88 citations

Mitogenic repression of myogenin autoregulation.

1991 • 64 citations

Activity of a kidney epithelial cell growth inhibitor on lung and mammary cells

1983 • 57 citations

Inhibition of myogenic differentiation by fibroblast growth factor or type β transforming growth factor does not require persistent c-myc expression

1987 • 42 citations