Integrin signaling to NF-kappa B in monocytic leukemia cells is blocked by activated oncogenes.

Oncogenes and signal transduction

1991 • 2,816 citations

Signal transduction from the extracellular matrix.

1993 • 1,727 citations

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1994 • 1,590 citations

Transcriptional Regulation by Extracellular signals: Mechanisms and Specificity

1995 • 1,287 citations

NF-κB: A lesson in family values

1995 • 1,266 citations

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

1989 • 1,073 citations

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

1991 • 746 citations

Integrin-mediated cell adhesion activates mitogen-activated protein kinases.

1994 • 660 citations

NF-kappa B activation by ultraviolet light not dependent on a nuclear signal

1993 • 646 citations

Raf meets Ras: completing the framework of a signal transduction pathway

1994 • 591 citations

Signal transduction by integrin receptors for extracellular matrix: cooperative processing of extracellular information

1992 • 532 citations

Adherence induces selective mRNA expression of monocyte mediators and proto-oncogenes.

1988 • 411 citations

Distinct Mechanisms for Regulation of the Interleukin-8 Gene Involve Synergism and Cooperativity between C/EBP and NF-κB

1993 • 400 citations

Involvement of integrin alpha V gene expression in human melanoma tumorigenicity.

1992 • 380 citations

Phosphorylation of the fibronectin receptor complex in cells transformed by oncogenes that encode tyrosine kinases.

1986 • 355 citations

The Ras signal transduction pathway

1994 • 345 citations

Expression of extracellular matrix components is regulated by substratum.

1990 • 345 citations

Rho family members: Activators of MAP kinase cascades

1995 • 253 citations

Integrin alpha 5 beta 1 expression negatively regulates cell growth: reversal by attachment to fibronectin.

1995 • 247 citations

Two Distinct Raf Domains Mediate Interaction with Ras

1995 • 243 citations

Definition of the human raf amino-terminal regulatory region by deletion mutagenesis.

1989 • 240 citations

Signal transduction by cell adhesion receptors

1995 • 239 citations

Integrin-mediated Tyrosine Phosphorylation and Cytokine Message Induction in Monocytic Cells

1995 • 228 citations

Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction.

1992 • 218 citations

Extracellular matrix and hormones transcriptionally regulate bovine beta-casein 5' sequences in stably transfected mouse mammary cells.

1990 • 217 citations

The alpha v beta 6 integrin promotes proliferation of colon carcinoma cells through a unique region of the beta 6 cytoplasmic domain.

1994 • 165 citations

Hypoxic activation of nuclear factor-kappa B is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2).

1994 • 151 citations

The role of protein tyrosine phosphorylation in integrin-mediated gene induction in monocytes.

1994 • 117 citations

Fibronectin attachment activates the NF-kappa B p50/p65 heterodimer in fibroblasts and smooth muscle cells.

1994 • 87 citations

Integrin regulation of an inflammatory effector gene. Direct induction of the tissue factor promoter by engagement of beta 1 or alpha 4 integrin chains.

1995 • 70 citations

Ras-15A protein shares highly similar dominant-negative biological properties with Ras-17N and forms a stable, guanine-nucleotide resistant complex with CDC25 exchange factor.

1994 • 69 citations

Effects of bacterial lipopolysaccharide on protein synthesis in murine peritoneal macrophages: Relationship to activation for macrophage tumoricidal function

1986 • 58 citations

[41] Ras-mediated transcription activation: Analysis by transient cotransfection assays

1995 • 51 citations

Increased amount of a 25-kilodalton phosphoprotein after v-mos transfection of CHO cells.

1988 • 3 citations