IgA Class Switch Occurs in the Organized Nasopharynx- and Gut-Associated Lymphoid Tissue, but Not in the Diffuse Lamina Propria of Airways and Gut

Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells

1999 • 1,149 citations

Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes.

1989 • 567 citations

Plasma-cell homing

2003 • 514 citations

Identification of Multiple Isolated Lymphoid Follicles on the Antimesenteric Wall of the Mouse Small Intestine

2002 • 460 citations

In situ class switching and differentiation to IgA-producing cells in the gut lamina propria

2001 • 428 citations

Regional specialization in the mucosal immune system: primed cells do not always home along the same track

1999 • 287 citations

Initiation of NALT Organogenesis Is Independent of the IL-7R, LTβR, and NIK Signaling Pathways but Requires the Id2 Gene and CD3−CD4+CD45+ Cells

2002 • 212 citations

Molecular Processes that Regulate Class Switching

2000 • 202 citations

Nasal Lymphoid Tissue (NALT) as a Mucosal Immune Inductive Site

1997 • 170 citations

A hallmark of active class switch recombination: Transcripts directed by I promoters on looped-out circular DNAs

2001 • 169 citations

Transforming growth factor-beta 1 is a costimulator for IgA production.

1990 • 134 citations

Nasal immune system: distinctive Th0 and Th1/Th2 type environments in murine nasal-associated lymphoid tissues and nasal passage, respectively

1998 • 120 citations

Nasopharyngeal-Associated Lymphoreticular Tissue (NALT) Immunity: Fimbriae-Specific Th1 and Th2 Cell-Regulated IgA Responses for the Inhibition of Bacterial Attachment to Epithelial Cells and Subsequent Inflammatory Cytokine Production

1999 • 119 citations

Nasal-Associated Lymphoid Tissue: Phenotypic and Functional Evidence for the Primary Role of Peripheral Node Addressin in Naive Lymphocyte Adhesion to High Endothelial Venules in a Mucosal Site

1999 • 112 citations

Cholera Toxin and its Subunits as Potential Oral Adjuvants

1989 • 101 citations

Deficiency of IL-5 receptor alpha-chain selectively influences the development of the common mucosal immune system independent IgA-producing B-1 cell in mucosa-associated tissues.

1999 • 99 citations

Effect of transforming growth factor (TGF)-beta 1 on IgA isotype expression. TGF-beta 1 induces a small increase in sIgA+ B cells regardless of the method of B cell activation.

1992 • 86 citations

IL-15 and IL-15 Receptor Selectively Regulate Differentiation of Common Mucosal Immune System-Independent B-1 Cells for IgA Responses

2000 • 82 citations

Deficiency of IL-5 Receptor α-Chain Selectively Influences the Development of the Common Mucosal Immune System Independent IgA-Producing B-1 Cell in Mucosa-Associated Tissues

1999 • 79 citations

Differential regulation of IgA production by TGF-β and IL-5: TGF-β induces surface IgA-positive cells bearing IL-5 receptor, whereas IL-5 promotes their survival and maturation into IgA-secreting cells

1992 • 74 citations