The Purification and Properties of Thymidylate Synthetase from Chick Embryo Extracts

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A Method for Determining the Sedimentation Behavior of Enzymes: Application to Protein Mixtures

1961 • 5,561 citations

The Role of Polyamines in the Neutralization of Bacteriophage Deoxyribonucleic Acid

1960 • 2,598 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆I. Nomenclature and rate equations

1963 • 2,095 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

1963 • 1,885 citations

Molecular Exclusion and Restricted Diffusion Processes in Molecular-Sieve Chromatography^*

1964 • 806 citations

THE MODE OF ACTION OF 5-FLUOROURACIL AND ITS DERIVATIVES

1958 • 634 citations

THE SYNTHESIS OF 5-FLUOROPYRIMIDINES

1957 • 494 citations

Crystalline Dihydropteroylglutamic Acid

1960 • 461 citations

2-Cyanoethyl Phosphate and its Use in the Synthesis of Phosphate Esters¹

1961 • 443 citations

Studies on fluorinated pyrimidines. II. Effects on transplanted tumors.

1958 • 436 citations

Studies on Fluorinated Pyrimidines

1961 • 419 citations

The Relationship between Michaelis Constants, Maximum Velocities and the Equilibrium Constant for an Enzyme-catalyzed Reaction

1953 • 301 citations

Enzyme Inhibition in Relation to Chemotherapy.

1949 • 260 citations

The Enzymatic Synthesis of Thymidylate

1962 • 219 citations

Direct Spectrophotometric Evidence for the Oxidation of Tetrahydrofolate during the Enzymatic Synthesis of Thymidylate

1961 • 209 citations

Fluorinated pyrimidines. XXVI. Mammalian thymidylate synthetase: its mechanism of action and inhibition by fluorinated nucleotides.

1965 • 192 citations

Kinetic Studies of Yeast Hexokinase

1962 • 165 citations

A NEW ENZYME OF RNA SYNTHESIS: RNA METHYLASE

1962 • 149 citations

Procedure for simultaneous assay of two β-emitting isotopes with the liquid scintillation counting technique

1964 • 133 citations

Enzymic Preparation of the l,l-Diastereoisomer of Tetrahydrofolic Acid

1960 • 125 citations

On the Determination of Rate Constants for Coenzyme Mechanisms¹

1958 • 122 citations

The Enzymatic Synthesis of Thymidylate

1962 • 108 citations

The Purification and Properties of Deoxycytidylate Deaminase from Chick Embryo Extracts

1964 • 108 citations

Pyrimidine Nucleosides. I. A New Route for the Synthesis of Thymine Nucleosides¹

1956 • 100 citations

Determination of molecular weights and frictional ratios of macromolecules in impure systems: Aggregation of urease

1965 • 94 citations

Ribitol Dehydrogenase

1962 • 88 citations

The Biosynthesis of Thymidylic Acid

1963 • 77 citations

Spectrophotometric studies on the combination of formaldehyde with tetrahydropteroylglutamic acid and other hydropteridines

1960 • 76 citations

Virus-induced Acquisition of Metabolic Function

1962 • 72 citations

The Determination of Formaldehyde and Serine in Biological Systems

1958 • 67 citations

Inhibition of Phage-induced Thymidylate Synthetase by 5-Fluorodeoxyuridylate

1963 • 65 citations

The Enzymatic Synthesis of Thymidylate

1962 • 54 citations

Studies of fluorinated pyrimidines. XV. Inhibition of the incorporation of formate-C14 into DNA thymine of Ehrlich ascites carcinoma cells by 5-fluoro-2'-deoxyuridine-5'-monophosphate and related compounds.

1962 • 52 citations

The Reduction of Folate by Borohydride^*

1966 • 51 citations

The Biosynthesis of Thymidylic Acid

1962 • 49 citations

RESOLUTION OF PHAGE-INITIATED AND NORMAL HOST THYMIDYLATE SYNTHETASES OF ESCHERICHIA COLI

1962 • 39 citations

Mechanism of the Action of Thymidylate Synthetase

1960 • 27 citations

Further Studies on Thymidylate Synthetase from Calf Thymus

1963 • 20 citations

FOLIC ACID REDUCTASE

1957 • 19 citations

On the Mechanism of Chemical and Enzymatic Reduction of Folate and Dihydrofolate

1966 • 18 citations

Nucleotide interconversions. VI. The enzymic formation of 5-methyluridylic acid

1962 • 16 citations