Studies on Fluorinated Pyrimidines

The Determination of Enzyme Dissociation Constants

1934 • 11,865 citations

THE MODE OF ACTION OF 5-FLUOROURACIL AND ITS DERIVATIVES

1958 • 634 citations

Specific Binding of 4-Amino Folic Acid Analogues by Folic Acid Reductase

1961 • 389 citations

Enzyme Inhibition in Relation to Chemotherapy.

1949 • 260 citations

Direct Spectrophotometric Evidence for the Oxidation of Tetrahydrofolate during the Enzymatic Synthesis of Thymidylate

1961 • 209 citations

Experiments with some mouse tumors and leukemias.

1958 • 201 citations

Nucleotide Interconversions

1960 • 186 citations

Studies on Fluorinated Pyrimidines

1959 • 184 citations

Studies on fluorinated pyrimidines. XI. In vitro studies on tumor resistance.

1960 • 119 citations

The Structure of “Active Formaldehyde” (N⁵, N¹⁰ -Methylene Tetrahydrofolic Acid)¹

1960 • 118 citations

Studies on the conversion of deoxyuridylic acid to thymidylic acid by a soluble extract from rat thymus

1958 • 104 citations

Virus-induced Acquisition of Metabolic Function

1959 • 102 citations

Possible Enzymic Mechanism for the Development of Resistance against Fluorouracil in Ascites Tumours

1959 • 92 citations

CONVERSION OF URACIL DEOXYRIBOSIDE TO THYMIDINE OF DEOXYRIBONUCLEIC ACID

1956 • 84 citations

Evidence for a Single Enzyme Reducing Folate and Dihydrofolate

1960 • 78 citations

Metabolism of uracil and 5-fluorouracil by drug-sensitive and by drug-resistant bacteria

1960 • 78 citations

SIMPLE SYNTHESES OF PYRIMIDINE-2'-DEOXY-RIBONUCLEOSIDES¹

1959 • 67 citations

Metabolism of Pyrimidine Arabinonucleosides and Cyclonucleosides in Escherichia coli

1960 • 65 citations

The Fluorometric Determination of Thymine in Deoxyribonucleic Acid and Derivatives

1958 • 59 citations

“CITROVORUM FACTOR” ACTIVITY OF TETRAHYDROPTEROYLGLUTAMIC ACID

1951 • 46 citations

The Methylation of Deoxyuridine¹

1957 • 46 citations

Studies on fluorinated pyrimidines. X. In vivo studies on tumor resistance.

1960 • 42 citations

Purification and Properties of Thymidylate Synthetase from Calf Thymus

1961 • 33 citations

Fluorinated Pyrimidines XII. Effects of Simple Nucleotides on Transplanted Tumors.

1960 • 19 citations

Automatic direct quantitation of radioactivity on paper chromatograms

1960 • 16 citations

Human cancer, the primary target.

1960 • 4 citations