Absence of Fenfluramine-Induced Anorexia and Reduced c-fos Induction in the Hypothalamus and Central Amygdaloid Complex of Serotonin 1B Receptor Knock-Out Mice

International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).

1994 • 2,935 citations

Stimulus-Transcription Coupling in the Nervous System: Involvement of the Inducible Proto-Oncogenes fos and jun

1991 • 2,666 citations

Increasing prevalence of overweight among US adults. The National Health and Nutrition Examination Surveys, 1960 to 1991

1994 • 2,623 citations

Expression of c- fos Protein in Brain: Metabolic Mapping at the Cellular Level

1988 • 1,916 citations

Increasing Prevalence of Overweight Among US Adults

1994 • 1,479 citations

Enhanced Aggressive Behavior in Mice Lacking 5-HT _1B Receptor

1994 • 823 citations

Amygdaloid and basal forebrain direct connections with the nucleus of the solitary tract and the dorsal motor nucleus

1982 • 432 citations

Serotonergic control of the organization of feeding and satiety

1995 • 419 citations

Amygdala and extended amygdala

1995 • 371 citations

The distribution and cells of origin of serotonergic inputs to the paraventricular and supraoptic nuclei of the rat

1983 • 369 citations

Elevated alcohol consumption in null mutant mice lacking 5–HT1B serotonin receptors

1996 • 356 citations

Species differences in the pharmacology of terminal 5-HT autoreceptors in mammalian brain

1989 • 354 citations

The mouse 5-hydroxytryptamine 1B receptor is localized predominantly on axon terminals

1994 • 346 citations

Localization of 5-HT1B, 5-HT1Dα, 5-HT1E and 5-HT1F receptor messenger RNA in rodent and primate brain

1994 • 343 citations

Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor

1998 • 329 citations

Neuronal localisation of neuropeptide Y gene expression in rat brain

1989 • 285 citations

The Amygdaloid Projection Field in the Rat as Studied with the Cupric-Silver Method

1972 • 279 citations

Evidence that hypophagia induced bymCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors

1988 • 257 citations

Stimulation of feeding by galanin: Anatomical localization and behavioral specificity of this peptide's effects in the brain

1990 • 253 citations

5-hydroxytryptamine1B receptors block the GABAB synaptic potential in rat dopamine neurons

1992 • 247 citations

Insights into the Neurobiology of Impulsive Behavior from Serotonin Receptor Knockout Mice

1997 • 237 citations

Autoradiographic characterisation and localisation of 5-HT1D compared to 5-HT1B binding sites in rat brain

1993 • 232 citations

5-HT1 receptor knock out — behavioral consequences

1995 • 201 citations

Cocaine inhibits GABA release in the VTA through endogenous 5-HT

1994 • 191 citations

Cholecystokinin Activates C‐Fos Expression in Hypothalamic Oxytocin and Corticotropin‐Releasing Hormone Neurons

1991 • 186 citations

Neurochemical-neuroendocrine systems in the brain controlling macronutrient intake and metabolism

1992 • 185 citations

Appetite Suppressants

1992 • 183 citations

5-HT1B agonists induce anorexia at a postsynaptic site

1987 • 176 citations

Medial hypothalamic nuclei mediate serotonin's inhibitory effect on feeding behavior

1990 • 162 citations

Appetite suppression by commonly used drugs depends on 5-HT receptors but not on 5-HT availability

1997 • 162 citations

Severe autosomal dominant hypertension and brachydactyly in a unique Turkish kindred maps to human chromosome 12

1996 • 143 citations

New players in the 5-HT receptor field: genes and knockouts

1995 • 126 citations

Characterisation of adjustments to the structure of feeding behaviour following pharmacological treatment: Effects of amphetamine and fenfluramine and the antagonism produced by pimozide and methergoline

1980 • 122 citations

Serotonergic projections from the nucleus raphe dorsalis to the amygdala in the rat

1991 • 120 citations

Evidence that d-fenfluramine anorexia is mediated by 5-HT1 receptors

1989 • 116 citations

Serotoninergic modulation of the pattern of eating and the profile of hunger-satiety in humans.

1987 • 111 citations

Infusion of the 5-hydroxytryptamine agonists RU24969 and TFMPP into the paraventricular nucleus of the hypothalamus causes hypophagia

1988 • 102 citations

Dexfenfluramine

1996 • 98 citations

Comparison of the metabolic and behavioral disturbances following paraventricular- and ventromedial-hypothalamic lesions

1985 • 97 citations

CP-94,253: a selective serotonin 1B (5-HT 1B ) agonist that promotes satiety

1997 • 92 citations

5-Hydroxytryptamine_1B Receptors Modulate the Effect of Cocaine on c-fos Expression: Converging Evidence Using 5-Hydroxytryptamine_1B Knockout Mice and the 5-Hydroxytryptamine_1B/1D Antagonist GR127935

1997 • 91 citations

A Cupric-silver Method for Impregnation of Terminal Axon Degeneration and its Further Use in Staining Granular Argyrophilic Neurons

1969 • 87 citations

Serotonin-1 receptor binding sites in the human basal ganglia are decreased in huntington's chorea but not in parkinson's disease: A quantitative in vitro autoradiography study

1989 • 85 citations

Dexfenfluramine induces fos-like immunoreactivity in discrete brain regions in rats

1993 • 83 citations

d-Fenfluramine- and d-norfenfluramine-induced hypophagia: differential mechanisms and involvement of postsynaptic 5-HT receptors

1993 • 82 citations

Comparative studies on the anorectic activity of d-fenfluramine in mice, rats, and guinea pigs

1991 • 81 citations

Importance of obesity.

1991 • 77 citations

Impact of hypothalamic d-norfenfluramine and peripheral d-fenfluramine injection on macronutrient intake in the rat

1990 • 62 citations

Role of noradrenaline and serotonin in the basolateral region of the amygdala in food preferences and learned taste aversions in the rat

1984 • 61 citations

Evidence that RU 24969‐induced locomotor activity in C57/B1/6 mice is specifically mediated by the 5‐HT_1B receptor

1993 • 61 citations

Role of 5-HT receptors in the effect of d-fenfluramine on feeding patterns in the rat

1992 • 57 citations

Effect of hypothalamic and peripheral fluoxetine injection on natural patterns of macronutrient intake in the rat

1991 • 54 citations

Acute migraine therapy

1997 • 51 citations

Distinct functions for dopamine and serotonin in locomotor behaviour: Evidence using the 5-HT1 agonist RU 24969 in globus pallidus-lesioned rats

1986 • 51 citations

5-Carboxamido-tryptamine, CP-122,288 and dihydroergotamine but not sumatriptan, CP-93,129, and serotonin-5-O-carboxymethyl-glycyl -tyrosinamide block dural plasma protein extravasation in knockout mice that lack 5-hydroxytryptamine1B receptors.

1996 • 49 citations

The 5-hydroxytryptamine agonist fenfluramine increases fos-like immunoreactivity in the brain

1992 • 45 citations

The 5-HT1B receptor mediates the effect of d-fenfluramine on eating caused by intra-hypothalamic injection of neuropeptide Y

1995 • 43 citations

Clinical Studies with Dexfenfluramine: From Past to Future

1995 • 43 citations

Fenfluramine-induced activation of the immediate-early gene c-fos in the striatum: possible interaction between serotonin and dopamine

1996 • 39 citations

Behavioural evidence thatd-fenfluramine-induced anorexia in the rat is not mediated by the 5-HT1A receptor subtype

1996 • 38 citations

Partial reversal of fluoxetine anorexia by the 5-HT antagonist metergoline

1992 • 36 citations

Radiofrequency lesions of the PVN fail to modify the effects of serotonergic drugs on food intake

1993 • 31 citations

Satiety function of neurons containing a CCK-like substance in the dorsal parabrachial nucleus

1990 • 27 citations

Suppression of behavioral activity by norfenfluramine and related drugs in rats is not mediated by serotonin release

1993 • 20 citations

Evidence for 5-HT2 receptor mediation in quipazine anorexia

1990 • 19 citations

Brain and feeding behavior

1988 • 9 citations

Induction of Fos-like immunoreactivity in the rat hypothalamus by an endogenous feeding suppressant (2-buten-4-olide)

1994 • 7 citations