Tissue-Specific Expression, Developmental Regulation, and Chromosomal Mapping of the Lecithin: Cholesterol Acyltransferase Gene

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Genomic sequencing.

1984 • 8,343 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

cDNA sequence of human apolipoprotein(a) is homologous to plasminogen

1987 • 1,842 citations

Methylmercury as a reversible denaturing agent for agarose gel electrophoresis

1976 • 1,323 citations

High-Efficiency Cloning of Full-Length cDNA

1982 • 1,309 citations

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

1987 • 696 citations

[20] Isolation of RNA using guanidinium salts

1987 • 614 citations

Variation in susceptibility to atherosclerosis among inbred strains of mice

1985 • 604 citations

The Biological Synthesis of Cholesterol

1965 • 524 citations

The mechanism of the plasma cholesterol esterification reaction: Plasma fatty acid transferase

1962 • 368 citations

CYTOMORPHOMETRY OF DEVELOPING RAT LIVER AND ITS APPLICATION TO ENZYMIC DIFFERENTIATION

1972 • 317 citations

Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice.

1987 • 286 citations

Expression of rat apolipoprotein A-IV and A-I genes: mRNA induction during development and in response to glucocorticoids and insulin.

1985 • 231 citations

Genetic factors affecting blood lipoproteins: the candidate gene approach.

1988 • 225 citations

Evidence for a lipoprotein carrier in human plasma catalyzing sterol efflux from cultured fibroblasts and its relationship to lecithin:cholesterol acyltransferase.

1981 • 197 citations

Human plasma lecithin-cholesterol acyltransferase. Characterization of cofactor-dependent phospholipase activity.

1978 • 180 citations

Cloning and expression of human lecithin-cholesterol acyltransferase cDNA.

1986 • 163 citations

Genetic factors controlling structure and expression of apolipoproteins B and E in mice.

1987 • 144 citations

Rat alpha 1-acid glycoprotein mRNA. Cloning of double-stranded cDNA and kinetics of induction of mRNA levels following acute inflammation.

1981 • 139 citations

Rat apolipoprotein E mRNA. Cloning and sequencing of double-stranded cDNA.

1983 • 137 citations

Genetic control of lipid transport in mice. II. Genes controlling structure of high density lipoproteins.

1983 • 137 citations

Tissue-specific expression and developmental regulation of the rat apolipoprotein B gene.

1986 • 132 citations

Cholesterol Transport Between Cells and Body Fluids: Role of Plasma Lipoproteins and the Plasma Cholesterol Esterification System

1982 • 130 citations

Human lecithin-cholesterol acyltransferase gene: complete gene sequence and sites of expression

1986 • 127 citations

Genetic and Developmental Regulation of the Lipoprotein Lipase Gene: Loci Both Distal and Proximal to the Lipoprotein Lipase Structural Gene Control Enzyme Expression

1989 • 113 citations

Characterization of the serine reacting with diethyl p-nitrophenyl phosphate in porcine pancreatic lipase

1981 • 89 citations

Weight standards for organs from early human fetuses

1971 • 86 citations

A mouse linkage testing stock possessing multiple copies of the endogenous ecotropic murine leukemia virus genome

1989 • 82 citations

Cellular differentiation in the emerging fetal rat small intestinal epithelium: mosaic patterns of gene expression.

1989 • 81 citations

Localization of mRNA for low density lipoprotein receptor and a cholesterol synthetic enzyme in rabbit nervous system by in situ hybridization.

1988 • 81 citations

The 1985 human gene map and human gene mapping in 1985

1985 • 75 citations

Regulation of rat liver 3-hydroxy-3-methylglutaryl coenzyme A synthase and the chromosomal localization of the human gene.

1986 • 73 citations

Nonspecific esterases of Mus musculus

1982 • 69 citations

Human plasma lecithin-cholesterol acyltransferase. The vicinal nature of cysteine 31 and cysteine 184 in the catalytic site.

1988 • 68 citations

Origin and disappearance of plasma lecithin: cholesterol acyltransferase

1971 • 62 citations

Production of lecithin: cholesterol acyltransferase by the isolated perfused rat liver

1970 • 61 citations

Transcriptional regulation of the 3-hydroxy-3-methylglutaryl coenzyme A reductase gene in rat liver.

1985 • 58 citations

Lipids and Lipoproteins in Maternal and Fetus Plasma in the Rat

1981 • 57 citations

Globin gene expression in erythroid human fetal liver cells.

1989 • 57 citations

Genetic mapping of ecotropic murine leukemia virus-inducing loci in six inbred strains.

1982 • 56 citations

Serum activity and hepatic secretion of lecithin:cholesterol acyltransferase in experimental hypothyroidism and hypercholesterolemia

1985 • 47 citations

A new location for the human adenine phosphoribosyltransferase gene (<i>APRT</i>) distal to the haptoglobin (<i>HP</i>) and fra(16)(q23) (<i>FRA16D</i>) loci

1986 • 42 citations

Plasma Lipoproteins and Lipase and LecithinrCholesterol Acyltransferase Activities in Obese Subjects Before and After Weight Reduction

1987 • 36 citations

Developmental changes in the expression of genes involved in cholesterol biosynthesis and lipid transport in human and rat fetal and neonatal livers

1989 • 36 citations

The structural gene for lecithin:cholesterol acyl transferase (LCAT) maps to 16q22

1987 • 34 citations

Chromosomal mapping of the structural gene coding for the mouse cell adhesion molecule uvomorulin.

1988 • 31 citations

Variations in the apolipoprotein AI-CIII-AIV gene region and in lecithin: cholesterol acyltransferase concentration are determinants of plasma cholesterol concentrations

1988 • 31 citations

Assignment of the human gene for cholesteryl ester transfer protein to chromosome 16q12–16q21

1987 • 31 citations

Identification of a novel sequence that governs both polyadenylation and alternative splicing in region E3 of adenovirus

1987 • 30 citations

Nephropathy of Familial Lecithin-Cholesterol Acyltransferase Deficiency: Report of a Case

1986 • 28 citations

Changes in lipoprgtein composition in women receiving two low-dose oral contraceptives containing ethinylestradiol and gonane prcgestins

1988 • 27 citations

Hormonal Regulation of Glycogen Metabolism in Human Fetal Liver: I. Normal Development and Effects of Dibutyryl Cyclic AMP, Glucagon, and Insulin in Liver Explants

1975 • 24 citations

Relationship of high density lipoprotein composition to plasma lecithin: cholesterol acyltransferase concentration in men

1988 • 24 citations

Functional size of the human asialoglycoprotein receptor as determined by radiation inactivation.

1984 • 23 citations

Lecithin: cholesterol acyl transferase activity in human cerebrospinal fluid

1970 • 21 citations

Mapping studies on human mitochondrial glutamate oxaloacetate transaminase

1982 • 20 citations

Genetic Heterogeneity in Familial Lecithin:Cholesterol Acyltransferase (LCAT) Deficiency

1981 • 19 citations

Report of the committee on comparative mapping

1988 • 17 citations

Lecithin-cholesterol acyltransferase in newborn infants: Low activity level in preterm infants

1988 • 17 citations

Identification of the active-site serine in human lecithin: Cholesterol acyltransferase

1988 • 15 citations

Hereditary lecithin-cholesterol acyltransferase deficiency. Report of 2 new cases and review of the literature.

1983 • 13 citations

Advantage of desogestrel containing pill in oral contraception: influence on blood lipids and LCAT activity.

1987 • 3 citations

Lack of association between plasma lecithin: cholesterol acyltransferase concentration and plasma sex hormone concentrations in men

1988 • 2 citations