Vitamin A and Lipofuscin

Handbook of Sensory Physiology

1975 • 7,212 citations

Histochemistry: Theoretical and Applied

1953 • 7,198 citations

Free Radicals in Biology

1976 • 1,879 citations

PARTICIPATION OF THE RETINAL PIGMENT EPITHELIUM IN THE ROD OUTER SEGMENT RENEWAL PROCESS

1969 • 1,156 citations

Chemistry and metabolism of lipids in the vertebrate retina

1983 • 1,034 citations

Molecular Basis of Visual Excitation

1968 • 1,002 citations

Histochemistry, Theoretical and Applied.

1972 • 960 citations

Handbook of Sensory Physiology,

1973 • 885 citations

Rod Outer Segment Disk Shedding in Rat Retina: Relationship to Cyclic Lighting

1976 • 665 citations

Aging human RPE: morphometric analysis of macular, equatorial, and peripheral cells.

1984 • 556 citations

Inherited Retinal Dystrophy: Primary Defect in Pigment Epithelium Determined with Experimental Rat Chimeras

1976 • 534 citations

THE BIOLOGICAL FUNCTION OF VITAMIN A ACID

1960 • 453 citations

The Oxygen Supply to the Retina, II. Effects of High Intraocular Pressure and of Increased Arterial Carbon Dioxide Tension on Uveal and Retinal Blood Flow in Cats

1972 • 409 citations

Lipofuscin and melanin of human retinal pigment epithelium. Fluorescence, enzyme cytochemical, and ultrastructural studies.

1978 • 394 citations

The topography and age relationship of lipofuscin concentration in the retinal pigment epithelium.

1978 • 384 citations

Free radicals, aging, and degenerative diseases

1987 • 375 citations

Vertebrate rod outer segment membranes

1973 • 352 citations

THE RENEWAL OF ROD AND CONE OUTER SEGMENTS IN THE RHESUS MONKEY

1971 • 351 citations

Free radicals, aging, and degenerative diseases

1986 • 311 citations

Retinal photoreceptor-pigment epithelium interactions. Friedenwald lecture.

1985 • 291 citations

Retinal Pigment Epithelial Abnormalities in Fundus Flavimmaculatus

1980 • 284 citations

Free radicals in molecular biology, aging, and disease

1985 • 271 citations

The Retinal Pigment Epithelium

1980 • 268 citations

VITAMIN A DEFICIENCY AND NIGHT BLINDNESS

1958 • 266 citations

LIPID PEROXIDATION AND FLUORESCENT MOLECULAR DAMAGE TO MEMBRANES

1975 • 266 citations

Role of the retinal pigment epithelium in macular disease.

1972 • 248 citations

Lipids of ocular tissues

1970 • 243 citations

Lipofuscin of Human Retinal Pigment Epithelium

1980 • 236 citations

A reinvestigation of the fatty acid content of bovine, rat and frog retinal rod outer segments

1979 • 232 citations

Effect of Antioxidants and Nutrients on Lipid Peroxidation Fluorescent Products and Aging Parameters in the Mouse

1973 • 224 citations

Evidence for rod outer segment lipid peroxidation following constant illumination of the rat retina.

1983 • 223 citations

Oxidative damage of retinal rod outer segment membranes and the role of vitamin E

1976 • 209 citations

Free Radicals in Molecular Biology, Aging, and Disease

1985 • 203 citations

Electron microscopic observations of human retinitis pigmentosa, dominantly inherited.

1974 • 182 citations

Transport of retinol from the blood to the retina: an autoradiographic study of the pigment epithelial cell surface receptor for plasma retinol-binding protein

1976 • 170 citations

Retinal degeneration in monkeys induced by deficiencies of vitamin E or A.

1974 • 170 citations

Vitamin A and the role of the pigment epithelium during bleaching and regeneration of rhodopsin in the frog eye

1976 • 166 citations

LIPOPROTEIN PIGMENTS—THEIR RELATIONSHIP TO AGEING IN THE HUMAN NERVOUS SYSTEM

1974 • 159 citations

Lipofuscin: Resolution of Discrepant Fluorescence Data

1982 • 149 citations

Influence of early photoreceptor degeneration on lipofuscin in the retinal pigment epithelium

1986 • 146 citations

Sex-linked retinitis pigmentosa: ultrastructure of photoreceptors and pigment epithelium.

1979 • 140 citations

The fate of the phagosome: conversion to 'age pigment' and impact in human retinal pigment epithelium.

1983 • 139 citations

Cataracts in the Royal College of Surgeons rat: Evidence for initiation by lipid peroxidation products

1985 • 139 citations

Vitamin E deficiency and the retina: photoreceptor and pigment epithelial changes.

1979 • 139 citations

PHOTORECEPTOR-PIGMENT EPITHELIAL CELL RELATIONSHIPS IN RATS WITH INHERITED RETINAL DEGENERATION

1972 • 130 citations

DISTRIBUTION OF VITAMIN A IN TISSUE AS VISUALIZED BY FLUORESCENCE MICROSCOPY

1944 • 129 citations

Fluorescent pigment accumulation in retinal pigment epithelium of antioxidant-deficient rats.

1978 • 128 citations

Retinal Metabolism in Dark and Light

1972 • 122 citations

Deficiencies of vitamins E and A in the rat. Retinal damage and lipofuscin accumulation.

1980 • 121 citations

The retinal oxygen profile in cats.

1983 • 119 citations

Effects of antioxidant nutrient deficiency on the retina and retinal pigment epithelium of albino rats: a light and electron microscopic study

1982 • 118 citations

Vitamin A Deficiency Effect on Retina: Dependence on Light

1971 • 118 citations

Lipofuscin: Fine-Structural and Biochemical Studies

1977 • 115 citations

Studies in Batten Disease

1974 • 111 citations

Age-related changes in the retinal pigment epithelium of pigmented rats

1984 • 110 citations

Oxygen supply to the retina from the retinal and choroidal circulations at normal and increased arterial oxygen tensions.

1969 • 106 citations

Identification of Retinoyl Complexes as the Autofluorescent Component of the Neuronal Storage Material in Batten Disease

1977 • 97 citations

Lipofuscin accumulation resulting from senescence and vitamin E deficiency: Spectral properties and tissue distribution

1984 • 96 citations

Pathobiology of Cell Membranes

1980 • 92 citations

Alpha-tocopherol in the retinal outer segment of bovine eyes

1970 • 80 citations

THE ROLES OF VITAMIN E AND UNSATURATED FATTY ACIDS IN THE VISUAL PROCESS

1982 • 76 citations

Structural and biochemical changes in vitamin A--deficient rat retinas.

1979 • 76 citations

Relationship between dietary retinol and lipofuscin in the retinal pigment epithelium

1986 • 70 citations

Vitamin E deficiency retinopathy in dogs.

1981 • 70 citations

Pigments in Pathology.

1969 • 69 citations

Oxygen transport in the bullfrog retina

1980 • 66 citations

Vitamin A in human eyes: amount, distribution, and composition.

1982 • 63 citations

THE ROLES OF VITAMIN E AND UNSATURATED FATTY ACIDS IN THE VISUAL PROCESS

1982 • 47 citations

Ocular Abnormalities in Abetalipoproteinemia

1984 • 47 citations

AN INVESTIGATION OF RETINAL AS A SOURCE OF SINGLET OXYGEN

1978 • 46 citations

α-Tocopherol in the developing rat retina: A high pressure liquid chromatographic analysis

1984 • 46 citations

Pathophysiology of vitamin E deficiency in monkeys1,2

1974 • 44 citations

Vitamin A storage and peroxisomes in retinal pigment epithelium and liver.

1977 • 43 citations

Rhodopsin chromophore exchanges among opsin molecules in the dark.

1983 • 43 citations

Autography in visual cells and pigment epithelium.

1977 • 42 citations

Lipids of bovine retinal pigment epithelium

1976 • 40 citations

Chemistry of photoreceptor membrane preparations from squid retinas

1978 • 36 citations

The neuronal ceroid-lipofuscinoses--Batten-Vogt syndrome: a model for human aging?

1971 • 34 citations

Essential fatty acid deficiency and renewal of rod outer segments in the albino rat.

1976 • 33 citations

New Aspects of the Ultrastructure of Frog Rod Outer Segments

1977 • 33 citations

Mechanisms of Ageing and Development

1979 • 29 citations

Pathophysiology of vitamin E deficiency in monkeys

1974 • 28 citations

Presence of cellular retinol and retinoic acid binding proteins in human uterus.

1975 • 28 citations

Lipofuscin in vitamin E deficiency and the possible role of retinol

1980 • 28 citations

Plasma tocopherol concentrations and vitamin E deficiency in dogs.

1970 • 26 citations

Production rate and removal of rod outer segment material in vitamin A deficiency.

1974 • 21 citations

Studies on the retina and the pigment epithelium in hereditary canine ceroid lipofuscinosis. III. Morphologic abnormalities in retinal neurons and retinal pigmented epithelial cells.

1980 • 21 citations

The Relationship between Membrane Fatty Acids and the Development of the Rat Retina

1977 • 21 citations

Isolation of plasma membranes from the bovine retinal pigment epithelium

1985 • 20 citations

Further studies on the chemistry of photoreceptor membranes of rats fed an essential fatty acid deficient diet

1975 • 18 citations

The structure of the eye III

1977 • 13 citations

Differential retinoid binding in chick pigment epithelium and choroid.

1979 • 13 citations

Influence of the Lipid Environment on the Properties of Rhodopsin in the Photoreceptor Membrane

1977 • 11 citations

Untersuchungen über den Vitamin-A-Stoffwechsel des Auges

1940 • 10 citations

Effects of moderate-intensity light on vitamin A-deficient rat retinas.

1981 • 8 citations

Photoreceptor outer segment and retinal pigment epithelium in vitamin E deficient rats

1981 • 8 citations

Lipofuscin accumulation in extraocular muscle of rats deficient in vitamins E and A

1985 • 8 citations

Deficiencies of vitamins E and A in the rat: lipofuscin accumulation in the choroid.

1984 • 7 citations

Deleted Work

1955 • 0 citations