A Pivotal Role of Rho GTPase in the Regulation of Morphology and Function of Dendritic Cells

Dendritic cells and the control of immunity

1998 • 14,345 citations

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

1997 • 2,847 citations

Reciprocal Control of T Helper Cell and Dendritic Cell Differentiation

1999 • 1,912 citations

Signaling from Rho to the Actin Cytoskeleton Through Protein Kinases ROCK and LIM-kinase

1999 • 1,581 citations

Prevention of Graft Versus Host Disease by Inactivation of Host Antigen-Presenting Cells

1999 • 1,218 citations

Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells

2000 • 1,175 citations

CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells.

1996 • 1,105 citations

Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization

2000 • 804 citations

The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells.

1990 • 799 citations

Role of Rho in Chemoattractant-Activated Leukocyte Adhesion Through Integrins

1996 • 494 citations

Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages

1997 • 415 citations

Dendritic Cells as the Terminal Stage of Monocyte Differentiation

1998 • 405 citations

Monocyte Adhesion and Spreading on Human Endothelial Cells Is Dependent on Rho-regulated Receptor Clustering

1999 • 269 citations

ICAM-1 Signaling Pathways Associated with Rho Activation in Microvascular Brain Endothelial Cells

1998 • 252 citations

Inhibition of PMA-induced, LFA-1-dependent lymphocyte aggregation by ADP ribosylation of the small molecular weight GTP binding protein, rho.

1993 • 223 citations

Activation of LFA-1 through a Ca2(+)-dependent epitope stimulates lymphocyte adhesion.

1991 • 223 citations

Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals.

1996 • 201 citations

RhoA-Dependent Phosphorylation and Relocalization of ERM Proteins into Apical Membrane/Actin Protrusions in Fibroblasts

1998 • 183 citations

Presentation of the Self Antigen Myelin Basic Protein by Dendritic Cells Leads to Experimental Autoimmune Encephalomyelitis

1999 • 166 citations

Constitutive and induced phosphorylation of the alpha- and beta-chains of the CD11/CD18 leukocyte integrin family. Relationship to adhesion-dependent functions.

1990 • 158 citations

Preparation of tetramethylrhodaminyl-phalloidin and uptake of the toxin into short-term cultured hepatocytes by endocytosis

1983 • 115 citations

Costimulation of T cell receptor/CD3-mediated activation of resting human CD4+ T cells by leukocyte function-associated antigen-1 ligand intercellular cell adhesion molecule-1 involves prolonged inositol phospholipid hydrolysis and sustained increase of intracellular Ca2+ levels.

1992 • 106 citations

Clostridium botulinum C3 ADP-ribosyltransferase gene. Cloning, sequencing, and expression of a functional protein in Escherichia coli.

1991 • 102 citations

CD28-Specific Antibody Prevents Graft-Versus-Host Disease in Mice

2000 • 99 citations

Fluorescent in vivo tracking of hematopoietic cells. Part I. Technical considerations

1989 • 95 citations

Rho is a negative regulator of human monocyte spreading.

1996 • 90 citations

Role of dendritic cells in the induction and maintenance of autoimmune diseases

1999 • 88 citations

Intercellular adhesion molecule‐3 is the predominant co‐stimulatory ligand for leukocyte function antigen‐1 on human blood dendritic cells

1995 • 81 citations

Characteristics of antigen‐independent and antigen‐dependent interaction of dendritic cells with CD4⁺ T cells

1995 • 57 citations

Suppression of Interleukin-12 Production by Human Monocytes After Preincubation With Lipopolysaccharide

1999 • 55 citations

IL-2, IL-4, and IFN-gamma gene expression versus secretion in superantigen-activated T cells. Distinct requirement for costimulatory signals through adhesion molecules.

1994 • 48 citations

Human blood dendritic cells: binding to vascular endothelium and expression of adhesion molecules

1997 • 46 citations

Constitutive up-regulation of integrin-mediated adhesion of tumor-infiltrating lymphocytes to osteoblasts and bone marrow-derived stromal cells.

1998 • 38 citations

Adenosine Diphosphate (ADP)-Ribosylation of the Guanosine Triphosphatase (GTPase) Rho in Resting Peripheral Blood Human T Lymphocytes Results in Pseudopodial Extension and the Inhibition of T Cell Activation

1998 • 34 citations

ADP-Ribosylation of Rho by C3 Ribosyltransferase Inhibits IL-2 Production and Sustained Calcium Influx in Activated T Cells

1999 • 31 citations

Use of lymphokine-activated killer cells to prevent bone marrow graft rejection and lethal graft-vs-host disease.

1989 • 31 citations

Induction of interleukin 12 responsiveness is impaired in anergic T lymphocytes.

1994 • 23 citations

Suppression of Interleukin-12 Production by Human Monocytes After Preincubation With Lipopolysaccharide

1999 • 12 citations

Human dendritic cells express the thrombopoietin receptor, c‐Mpl

1999 • 11 citations

Differential growth inhibition of isoquinolinesulfonamides H-8 and H-7 towards multidrug-resistant P388 murine leukaemia cells

1991 • 11 citations

Characterization of botulinum C3-catalyzed ADP- ribosylation of rho proteins and identification of mammalian C3-like ADP-ribosyltransferase

1994 • 9 citations

Fluorescent in vivo tracking of hematopoietic cells. Part I. Technical considerations

1989 • 6 citations

Immunologic Crosstalk

1999 • 6 citations