The covalent structure of mitochondrial aspartate aminotransferase from chicken. Identification of segments of the polypeptide chain invariant specifically in the mitochondrial isoenzyme.

The Preparation and Enzymatic Hydrolysis of Reduced and S-Carboxymethylated Proteins

1963 • 2,600 citations

Determination of Serum Glycoproteins

1955 • 1,078 citations

Micro‐sequence analysis of peptides and proteins using 4‐NN‐dimethylaminoazobenzene 4′‐isothiocyanate/phenylisothiocyanate double coupling method

1978 • 834 citations

[27] The cyanogen bromide reaction

1967 • 784 citations

The Low Polarity of Many Membrane Proteins

1972 • 498 citations

Polyquarternary amines prevent peptide loss from sequenators

1978 • 452 citations

Application of sequenator analysis to the study of proteins

1972 • 414 citations

Regeneration of amino acids from thiazolinones formed in the Edman degradation

1975 • 394 citations

Automated amino acid sequence of small peptides utilizing Polybrene

1978 • 323 citations

On the Aminoethylation of Proteins

1966 • 315 citations

Advances in the gas chromatographic analysis of amino acid phenyl- and methylthiohydantoins

1972 • 307 citations

Three-dimensional structure of a pyridoxal-phosphate-dependent enzyme, mitochondrial aspartate aminotransferase.

1980 • 242 citations

The complete amino acid sequence of cytoplasmic aspartate aminotransferase from pig heart

1973 • 201 citations

[49] Reaction of proteins with citraconic anhydride

1972 • 177 citations

Nucleotide sequence of the trpB gene in Escherichia coli and Salmonella typhimurium

1980 • 151 citations

Identifizierung von PTH-Aminosäuren mit Hilfe der schnellen Flüssigkeits-Chromatographie

1973 • 132 citations

Comparative Studies on Glutamic-Oxalacetic Transaminases from the Mitochondrial and Soluble Fractions of Mammalian Tissues

1964 • 132 citations

10 Amino Group Transfer

1973 • 114 citations

[33] S-Aminoethylation

1967 • 112 citations

The primary structure of aspartate aminotransferase from pig heart muscle. Digestion with a proteinase having specificity for lysine residues

1975 • 96 citations

Aeromonas Aminopeptidase

1971 • 85 citations

Isolation, crystallization and preliminary crystallographic data of aspartate aminotransferase from chicken heart mitochondria

1977 • 74 citations

Stereochemistry of pyridoxal phosphate catalyzed enzyme reactions

1980 • 73 citations

Pyridoxal 5'-phosphate binding site of pig heart alanine aminotransferase

1979 • 70 citations

Biosynthesis and topogenesis of aspartate aminotransferase isoenzymes in chicken embryo fibroblasts. The precursor of the mitochondrial isoenzyme is either imported into mitochondria or degraded in the cytosol.

1982 • 63 citations

Cell-free synthesis of a putative precursor of mitochondrial aspartate aminotransferase with higher molecular weight

1980 • 61 citations

Biosynthesis of aspartate aminotransferases. Both the higher molecular weight precursor of mitochondrial aspartate aminotransferase and the cytosolic isoenzyme are synthesized on free polysomes.

1982 • 60 citations

Molecular structure and biological activity

1983 • 59 citations

Syncatalytic conformational changes in mitochondrial aspartate aminotransferases. Evidence from modification and demodification of Cys 166 in the enzyme from chicken and pig.

1978 • 58 citations

A new, improved technique for automated sequencing of non-polar peptides

1973 • 57 citations

The Chemical Structure of Tryptophanase from Escherichia coli

1970 • 48 citations

Primary structure of cytoplasmic aspartate aminotransferase from chicken heart and its homology with pig heart isoenzymes

1979 • 47 citations

Comparison of the evolution rates of cytosolic and mitochondrial aspartate aminotransferase

1978 • 47 citations

The Cytosolic and Mitochondrial Aspartate Aminotransferases from Pig Heart. A Comparison of their Primary Structures, Predicted Secondary Structures and Some Physical Properties

1980 • 47 citations

[48] Leucine aminopeptidase (LAP)

1967 • 46 citations

Simultaneous Isolation and Characterization of Chicken Supernatant and Mitochondrial Isoenzymes of Aspartate Transaminase

1973 • 45 citations

Cytosolic and mitochondrial isoenzymes of glutamic-oxalacetic transaminase from human heart. Structural comparison with the isoenzymes from pig heart.

1978 • 45 citations

Electron density map of chicken heart cytosol aspartate transaminase at 3.5 Å resolution

1980 • 45 citations

Active-site labeling of aspartate aminotransferases by the β,γ-unsaturated amino acid vinylglycine

1977 • 44 citations

Interspecies comparison of cytosolic and mitochondrial aspartate aminotransferases. Evidence for a more conservative evolution of the mitochondrial isoenzyme.

1977 • 43 citations

Complete amino acid sequence of mitochondrial aspartate aminotransferase from pig heart muscle. Peptide ordering procedures and the complete sequence.

1980 • 42 citations

Precipitation of complexes between glutamate dehydrogenase and mitochondrial enzymes.

1979 • 41 citations

Three‐dimensional structure at 3.2 Å resolution of the complex of cytosolic aspartate aminotransferase from chicken heart with 2‐oxoglutarate

1982 • 39 citations

Mitochondrial Aspartate Aminotransferase from Beef Kidney

1972 • 36 citations

[118] Sequence methods

1963 • 35 citations

Microsequence analysis: I. Peptide isolation using high‐performance liquid chromatography

1979 • 35 citations

The Chemical Structure of Tryptophanase from Escherichia coli

1972 • 32 citations

The structure of mitochrondrial aspartate aminotransferase from pig heart and comparison with that of the cytoplasmic isozyme

1977 • 30 citations

Sequence of Escherichia coli D‐serine dehydratase

1981 • 26 citations

Microsequence analysis: III. Automatic solid‐phase sequencing using dabitc

1979 • 26 citations

Primary structure of mitochondrial glutamic oxaloacetic transaminase from rat liver: Comparison with that of the pig heart isozyme

1980 • 25 citations

Independent quantitation of the mitochondrial and the cytosolic isoenzyme of aspartate aminotransferase in chicken tissues by radioimmunoassays.

1981 • 25 citations

Conspicuous degree of homology between the mitochondrial aspartate aminotransferases from chicken and pig heart

1975 • 21 citations

Paracatalytic modification of aldolase: A side reaction of the catalytic cycle resulting in irreversible blocking of two active-site lysyl residues

1979 • 21 citations

Mitochondrial bovine aspartate aminotransferase

1979 • 20 citations

Further microheterogeneity of cytoplasmic aspartate aminotransferase from pig heart

1968 • 16 citations

Carbohydrate components of aspartate transaminase: Multiple forms of the enzyme from pig heart cytosol

1973 • 16 citations

Sequence Studies on <scp>d</scp>‐Serine Dehydratase of Escherichia coli

1976 • 15 citations

Primary structure of mitochondrial aspartate aminotransferase from turkey liver

1979 • 13 citations

The sequences of the coenzyme-binding peptide in the cytoplasmic and the mitochondrial aspartate aminotransferases from sheep liver

1975 • 12 citations

Aspartate transaminase from E.coli: Amino acid sequences of the NH2-terminal 33 residues and chymotryptic pyridoxyl tetrapeptide

1979 • 12 citations

Microsequence analysis: IV. Automatic liquid‐phase sequencing using dabitc

1979 • 9 citations

A diagonal procedure for isolating sulfhydryl peptides alkylated with N-ethylmaleimide

1980 • 8 citations