Syncatalytic conformational changes in mitochondrial aspartate aminotransferases. Evidence from modification and demodification of Cys 166 in the enzyme from chicken and pig.

Tissue sulfhydryl groups

1959 • 25,130 citations

Strategy and tactics in protein chemistry

1970 • 1,226 citations

Evidence for Nonidentical Chains in the β-Galactosidase of Escherichia coli K12

1965 • 450 citations

[20] Reduction and S-carboxymethylation of proteins

1967 • 414 citations

Reactions of N-ethylmaleimide with peptides and amino acids

1964 • 396 citations

A Kinetic and Equilibrium Analysis of the Glutamic Oxaloacetate Transaminase Mechanism

1962 • 348 citations

[15] Cleavage at aspartylprolyl bonds

1977 • 319 citations

Some Reactions of N-Ethylmaleimide¹

1960 • 277 citations

The complete amino acid sequence of cytoplasmic aspartate aminotransferase from pig heart

1973 • 201 citations

Cytoplasmic Aspartate Aminotransferase: Syncatalytic Sulfhydryl Group Modification

1973 • 148 citations

Sequence Analysis of Fluorescamine‐Stained Peptides and Proteins Purified on a Nanomole Scale

1974 • 147 citations

Human Heart Cytochrome c

1963 • 119 citations

THE REACTION OF IODOACETATE AND OF IODOACETAMIDE WITH VARIOUS SULFHYDRYL GROUPS, WITH UREASE, AND WITH YEAST PREPARATIONS

1936 • 113 citations

[63] Reactions with N-ethylmaleimide and p-mercuribenzoate

1967 • 99 citations

The Interaction of Aspartate Aminotransferase with α-Methylaspartic Acid^*

1966 • 91 citations

Aeromonas Aminopeptidase

1971 • 85 citations

Glutamic-Aspartic Transaminase

1964 • 81 citations

Isolation, crystallization and preliminary crystallographic data of aspartate aminotransferase from chicken heart mitochondria

1977 • 74 citations

The Complete Amino Acid Sequence of Mitochondrial Aspartate Aminotransferase from Pig Heart1

1977 • 60 citations

Kinetic investigation of the interaction of erythro-β-hydroxyaspartic acid with aspartate aminotransferase

1969 • 55 citations

Simultaneous Isolation and Characterization of Chicken Supernatant and Mitochondrial Isoenzymes of Aspartate Transaminase

1973 • 45 citations

Interspecies comparison of cytosolic and mitochondrial aspartate aminotransferases. Evidence for a more conservative evolution of the mitochondrial isoenzyme.

1977 • 43 citations

The primary structure of aspartate aminotransferase from pig heart muscle determined in part using a protease with specificity for lysine

1974 • 38 citations

Syncatalytic sulfhydryl group modification in mitochondrial aspartate aminotransferase from chicken and pig heart

1975 • 31 citations

Conspicuous degree of homology between the mitochondrial aspartate aminotransferases from chicken and pig heart

1975 • 21 citations

Syncatalytic conformational changes in aspartate aminotransferase determined by hydrogen-deuterium exchange.

1978 • 21 citations

On the stability of N-ethylmaleimide alkylated sulfhydrylgroups

1972 • 20 citations

Selective modification of the mitochondrial isozyme of aspartate aminotransferase by .beta.-bromopropionate. I. Inactivation process and properties of inactivated enzyme

1972 • 18 citations

[4] Syncatalytic enzyme modification: Characteristic features and differentiation from affinity labeling

1977 • 9 citations

Reactivity of the cysteine and tyrosine residues of aspartate transaminase from chicken heart cytosol

1975 • 8 citations

Identification of the reactive sulphydryl group of mitochondrial aspartate aminotransferase from pig heart

1976 • 3 citations