Phosphatidylcholine is a major source of phosphatidic acid and diacylglycerol in angiotensin II-stimulated vascular smooth-muscle cells

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Hypertension: Pathophysiology, Diagnosis, and Management

1991 • 940 citations

The regulation and cellular functions of phosphatidylcholine hydrolysis

1990 • 862 citations

Growth factor-like action of phosphatidic acid

1986 • 531 citations

Sustained diacylglycerol formation from inositol phospholipids in angiotensin II-stimulated vascular smooth muscle cells.

1986 • 491 citations

Phosphatidylcholine Hydrolysis by Phospholipase D Determines Phosphatidate and Diglyceride Levels in Chemotactic Peptide-stimulated Human Neutrophils

1989 • 429 citations

Cellular ras activity and phospholipid metabolism

1988 • 331 citations

The Effect of GTPase Activating Protein Upon Ras Is Inhibited by Mitogenically Responsive Lipids

1989 • 287 citations

Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suramin

1992 • 266 citations

Angiotensin increases inositol trisphosphate and calcium in vascular smooth muscle.

1985 • 241 citations

Phorbol ester and 1-oleoyl-2-acetylglycerol inhibit angiotensin activation of phospholipase C in cultured vascular smooth muscle cells.

1985 • 240 citations

Kinetic analysis of 1,2-diacylglycerol mass levels in cultured fibroblasts. Comparison of stimulation by alpha-thrombin and epidermal growth factor.

1988 • 207 citations

Correlation of receptor sequestration with sustained diacylglycerol accumulation in angiotensin II-stimulated cultured vascular smooth muscle cells.

1987 • 161 citations

Porcine 80-kDa diacylglycerol kinase is a calcium-binding and calcium/phospholipid-dependent enzyme and undergoes calcium-dependent translocation.

1991 • 131 citations

Dissociation of protein kinase C activation and sn-1,2-diacylglycerol formation. Comparison of phosphatidylinositol- and phosphatidylcholine-derived diglycerides in alpha-thrombin-stimulated fibroblasts.

1991 • 120 citations

Molecular species analysis of mitogen-stimulated 1,2-diglycerides in fibroblasts. Comparison of alpha-thrombin, epidermal growth factor, and platelet-derived growth factor.

1990 • 110 citations

Further studies on the specificity of diacylglycerol for protein kinase C activation

1987 • 106 citations

Angiotensin II-induced phosphatidylcholine hydrolysis in cultured vascular smooth-muscle cells. Regulation and localization

1991 • 98 citations

Stimulation of phosphatidylinositol 4,5-bisphosphate phospholipase C activity by phosphatidic acid

1989 • 88 citations

Second messenger function of phosphatidic acid in platelet activation

1989 • 86 citations

The sustained second phase of hormone-stimulated diacylglycerol accumulation does not activate protein kinase C in GH3 cells.

1990 • 82 citations

Down-regulation of protein kinase C potentiates angiotensin II-stimulated polyphosphoinositide hydrolysis in vascular smooth-muscle cells

1989 • 69 citations

Phospholipids containing polyunsaturated fatty acyl groups are mitogenic for normal mouse mammary epithelial cells in serum-free primary cell culture.

1989 • 62 citations

Evidence that Na+/H+ exchange regulates angiotensin II-stimulated diacylglycerol accumulation in vascular smooth muscle cells.

1988 • 35 citations

Diacylglycerol metabolism in isolated aortic smooth muscle cells

1989 • 33 citations

The mitogenic activities of phosphatidate are acyl-chain-length dependent and calcium independent in C3H/10T1/2 cells.

1991 • 27 citations

Angiotensin II stimulates vimentin phosphorylation via a Ca2+-dependent, protein kinase C-independent mechanism in cultured vascular smooth muscle cells.

1988 • 26 citations

Phosphatidate Phosphohydrolase (1988)

2017 • 26 citations

Rapid desensitization of vasopressin-stimulated phosphatidylinositol 4,5-bisphosphate and phosphatidylcholine hydrolysis questions the role of these pathways in sustained diacylglycerol formation in A10 vascular-smooth-muscle cells

1992 • 26 citations

Quantitative analysis of retinal glycerolipid molecular species acetylated by acetolysis.

1989 • 15 citations

Protein kinase C does not regulate diacylglycerol metabolism in aortic smooth muscle cells

1990 • 9 citations