MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans
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The Nematode Caenorhabditis elegans
1988 • 2,868 citations
Mammalian Telomeres End in a Large Duplex Loop
1999 • 2,372 citations
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
1997 • 2,086 citations
TRF2 Protects Human Telomeres from End-to-End Fusions
1998 • 1,679 citations
THE STABILITY OF BROKEN ENDS OF CHROMOSOMES IN ZEA MAYS
1941 • 1,586 citations
Essential role of mouse telomerase in highly proliferative organs
1998 • 1,256 citations
The telomere terminal transferase of tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
1987 • 1,127 citations
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 • 969 citations
An alternative pathway for yeast telomere maintenance rescues est1− senescence
1993 • 916 citations
A mutant with a defect in telomere elongation leads to senescence in yeast
1989 • 905 citations
Loss of a yeast telomere: Arrest, recovery, and chromosome loss
1993 • 787 citations
NONDISJUNCTION MUTANTS OF THE NEMATODE CAENORHABDITIS ELEGANS
1979 • 768 citations
Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
1998 • 636 citations
Cdc13p: A Single-Strand Telomeric DNA-Binding Protein with a Dual Role in Yeast Telomere Maintenance
1996 • 592 citations
Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance
1996 • 478 citations
Relocalization of Telomeric Ku and SIR Proteins in Response to DNA Strand Breaks in Yeast
1999 • 458 citations
The telomerase reverse transcriptase: components and regulation
1998 • 435 citations
Yeast Checkpoint Genes in DNA Damage Processing: Implications for Repair and Arrest
1995 • 418 citations
DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe.
1992 • 417 citations
Saccharomyces telomeres acquire single-strand TG1–3 tails late in S phase
1993 • 407 citations
Immunofluorescence visualization of germ-line-specific cytoplasmic granules in embryos, larvae, and adults of Caenorhabditis elegans.
1982 • 392 citations
Natural Variation and Copulatory Plug Formation in Caenorhabditis elegans
1997 • 392 citations
SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres
1993 • 392 citations
TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene
1995 • 386 citations
Fission yeast genes involved in coupling mitosis to completion of DNA replication.
1992 • 382 citations
ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase
1997 • 376 citations
TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1
1995 • 370 citations
Telomere maintenance is dependent on activities required for end repair of double-strand breaks
1998 • 369 citations
Germ Cells
1999 • 348 citations
MEC1-Dependent Redistribution of the Sir3 Silencing Protein from Telomeres to DNA Double-Strand Breaks
1999 • 332 citations
Two Modes of Survival of Fission Yeast Without Telomerase
1998 • 289 citations
Segregation of holocentric chromosomes at meiosis in the nematode,Caenorhabditis elegans
1993 • 276 citations
Interactions of TLC1 (Which Encodes the RNA Subunit of Telomerase), TEL1, and MEC1 in Regulating Telomere Length in the Yeast Saccharomyces cerevisiae
1999 • 264 citations
Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint.
1993 • 263 citations
Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability
1999 • 255 citations
The DNA-binding Protein Hdf1p (a Putative Ku Homologue) Is Required for Maintaining Normal Telomere Length in Saccharomyces Cerevisiae
1996 • 246 citations
Circular chromosome formation in a fission yeast mutant defective in two ATM homologues
1998 • 231 citations
Chapter 2 Mutagenesis
1995 • 159 citations
Telomeric repeats (TTAGGC)n are sufficient for chromosome capping function in Caenorhabditis elegans.
1996 • 114 citations
Human and mouse homologs ofSchizosaccharomyces pombe rad1+andSaccharomyces cerevisiae RAD17:linkage to checkpoint control and mammalian meiosis
1998 • 110 citations
Genetic Control of Telomere Integrity in Schizosaccharomyces pombe: rad3+ and tel1+ Are Parts of Two Regulatory Networks Independent of the Downstream Protein Kinases chk1+ and cds1+
1999 • 67 citations
Regulation of Telomere Length by Checkpoint Genes inSchizosaccharomyces pombe
1998 • 67 citations
cDNA Cloning and Gene Mapping of Human Homologs forSchizosaccharomyces pombe rad17, rad1,andhus1and Cloning of Homologs from Mouse,Caenorhabditis elegans,andDrosophila melanogaster
1998 • 47 citations
DOMINANT X-CHROMOSOME NONDISJUNCTION MUTANTS OF CAENORHABDITIS ELEGANS
1982 • 44 citations
Telomerase RNA localized in the replication band and spherical subnuclear organelles in hypotrichous ciliates.
1995 • 40 citations
Human and Mouse Homologs of theSchizosaccharomyces pombe rad17+Cell Cycle Checkpoint Control Gene
1999 • 30 citations
Normal telomere maintenance in immortal ataxia telangiectasia cell lines
1997 • 29 citations
RAD1,a Human Structural Homolog of theSchizosaccharomyces pombe RAD1Cell Cycle Checkpoint Gene
1998 • 27 citations
A Human and Mouse Homolog of theSchizosaccharomyces pombe rad1+Cell Cycle Checkpoint Control Gene
1998 • 18 citations
Transposons -- C. elegans II
1997 • 6 citations
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