Control of Extracellular Matrix Degradation by Interferon-γ

Relationship between interferon‐γ, indoleamine 2,3‐dioxygenase, and tryptophan catabolism

1991 • 1,018 citations

IFN-gamma-mediated antimicrobial response. Indoleamine 2,3-dioxygenase-deficient mutant host cells no longer inhibit intracellular Chlamydia spp. or Toxoplasma growth.

1993 • 146 citations

Antiparasitic and antiproliferative effects of indoleamine 2,3-dioxygenase enzyme expression in human fibroblasts

1994 • 118 citations

Interferon‐γ reverses the stimulation of collagen but not fibronectin gene expression by transforming growth factor‐ β in normal human fibroblasts

1990 • 89 citations

Interferon‐γ reverses the stimulation of collagen but not fibronectin gene expression by transforming growth factor‐β in normal human fibroblasts

1990 • 71 citations

Interferon gamma-resistant mutants are defective in the induction of indoleamine 2,3-dioxygenase.

1989 • 61 citations

Recent Progress in the Elucidation of Interferon-Gamma Actions: Molecular Biology and Biological Functions

1994 • 36 citations

c-fos mRNA Expression in Macrophages Is Downregulated by Interferon-γ at the Posttranscriptional Level

1991 • 34 citations

c-fos mRNA expression in macrophages is downregulated by interferon-gamma at the posttranscriptional level.

1991 • 20 citations

L-Tryptophan in supraphysiologic concentrations stimulates collagenase gene expression in human skin fibroblasts.

1994 • 19 citations