Genetic complementation among inherited deficiencies of methylmalonyl-CoA mutase activity: evidence for a new class of human cobalamin mutant.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Fluorometric assay of proteins in the nanogram range

1973 • 1,640 citations

Production of mammalian somatic cell hybrids by means of polyethylene glycol treatment

1975 • 549 citations

Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol

1976 • 542 citations

On the nature of hereditable variation in cultured somatic cells

1976 • 497 citations

Hurler and Hunter Syndromes: Mutual Correction of the Defect in Cultured Fibroblasts

1968 • 437 citations

Polyethylene glycol-induced mammalian cell hybridization: Effect of polyethylene glycol molecular weight and concentration

1976 • 300 citations

High in vivo rates of methionine biosynthesis in transformed human and malignant rat cells auxotrophic for methionine.

1976 • 266 citations

Five complementation groups in xeroderma pigmentosum

1975 • 199 citations

Methylmalonic Aciduria: Metabolic Block Localization and Vitamin B ₁₂ Dependency

1968 • 146 citations

Homocystinuria with methylmalonic aciduria: Two cases in a sibship

1970 • 137 citations

GENETICS OF SOMATIC MAMMALIAN CELLS, X. COMPLEMENTATION ANALYSIS OF GLYCINE-REQUIRING MUTANTS

1969 • 135 citations

Rapid prenatal and postnatal detection of inborn errors of propionate, methylmalonate, and cobalamin metabolism: A sensitive assay using cultured cells

1976 • 124 citations

Genetic heterogeneity in GM1-gangliosidosis

1975 • 107 citations

CONGENITAL METHYLMALONIC ACIDEMIA: ENZYMATIC EVIDENCE FOR TWO FORMS OF THE DISEASE

1969 • 105 citations

Genetic complementation of propionyl-CoA carboxylase deficiency in cultured human fibroblasts.

1977 • 104 citations

Genetic complementation in heterokaryons of human fibroblasts defective in cobalamin metabolism.

1975 • 102 citations

Mutant alleles for hypoxanthine phosphoribosyltransferase: Codominant expression, complementation, and segregation in hybrid Chinese hamster cells

1976 • 85 citations

Activation of methionine synthase: Further characterization of the flavoprotein system

1977 • 84 citations

Methylmalonicacidemia: biochemical heterogeneity in defects of 5'-deoxyadenosylcobalamin synthesis.

1975 • 83 citations

Interallelic Complementation in Hybrid Cells Derived from Human Diploid Strains Deficient in Galactose-1-Phosphate Uridyl Transferase Activity

1970 • 81 citations

Mental Retardation, Megaloblastic Anaemia, Methylmalonic Aciduria and Abnormal Homocysteine Metabolism Due to an Error in Vitamin B12 Metabolism

1974 • 79 citations

Intracellular binding of radioactive hydroxocobalamin to cobalamin-dependent apoenzymes in rat liver.

1977 • 78 citations

Deranged B12 metabolism: Effects on sulfur amino acid metabolism

1970 • 77 citations

Tay-Sachs and Sandhoff's disease: Intergenic complementation after somatic cell hybridization

1974 • 75 citations

Defective metabolism of vitamin B12 in fibroblasts from children with methylmalonicaciduria

1971 • 73 citations

Genetic complementation after fusion of Tay-Sachs and Sandhoff cells

1974 • 71 citations

Deranged B12 metabolism: Studies of fibroblasts grown in tissue culture

1970 • 70 citations

Time and mode of fusion of human fibroblasts treated with polyethylene glycol (PEG)

1977 • 67 citations

Genetics of Somatic Mammalian Cells: Biochemical Genetics of Chinese Hamster Cell Mutants with Deviant Purine Metabolism

1974 • 63 citations

Complementation Analysis of Maple Syrup Urine Disease in Heterokaryons derived from Cultured Human Fibroblasts

1973 • 53 citations

Synthesis of cobalamin coenzymes by human cells in tissue culture.

1971 • 43 citations

Absence of an intracellular cobalamin-binding protein in cultured fibroblasts from patients with defective synthesis of 5′-deoxyadenosylcobalamin and methylcobalamin

1975 • 37 citations

Cobalamins in Fibroblasts Cultured from Normal Control Subjects and Patients with Methylmalonic Aciduria

1976 • 35 citations

Heterogeneity in maple syrup urine disease: Aspects of cofactor requirement and complementation in cultured fibroblasts

1977 • 18 citations

Mutants of purine metabolism in cultured mouse and hamster cells

1976 • 12 citations