Selective early loss of polypeptides in liver microsomes of CCl4-treated rats

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 3,435 citations

Free Radical Mechanisms in Tissue Injury

1988 • 1,585 citations

Carbon Tetrachloride Hepatotoxicity: An Example of Lethal Cleavage

1973 • 729 citations

Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450

1976 • 536 citations

ADP-activated lipid peroxidation coupled to the TPNH oxidase system of microsomes

1963 • 512 citations

Necrogenic Action of Carbon Tetrachloride in the Rat: A Speculative Mechanism Based on Activation

1966 • 457 citations

Early onset of lipoperoxidation in rat liver after carbon tetrachloride administration

1968 • 360 citations

Lipid peroxidation and the degradation of cytochrome P-450 heme

1973 • 224 citations

Specificity of a phenobarbital-induced cytochrome P-450 for metabolism of carbon tetrachloride to the trichloromethyl radical

1982 • 182 citations

Confirmation of assignment of the trichloromethyl radical spin adduct detected by spin trapping during 13C-carbon tetrachloride metabolism , , , ,

1980 • 165 citations

A simple and rapid procedure for the purification of phenobarbitalinducible cytochrome P-450 from rat liver microsomes

1979 • 163 citations

Spin-trapping of the trichloromethyl radical produced during enzymic NADPH oxidation in the presence of carbon tetrachloride or bromotrichloromethane

1978 • 155 citations

In vivo spin-trapping of trichloromethyl radicals formed from CCl4

1979 • 106 citations

Incorporation of radioactive-δ-aminolevulinic acid into microsomal cytochrome P450: Selective breakdown of the hemoprotein by allylisopropylacetamide and carbon tetrachloride

1972 • 79 citations

Iron‐dependent loss of liver cytochrome P‐450 haem in vivo and in vitro

1973 • 59 citations

Loss of haem from cytochrome P-450 caused by lipid peroxidation and 2-allyl-2-isoprophylacetamide. An abnormal pathway not involving production of carbon monoxide

1977 • 40 citations

Effect of drug pretreatment on carbon tetrachloride-induced lipid peroxidation in rat liver microsomal lipids

1970 • 40 citations

Degradation of cytochrome P-450 haem by carbon tetrachloride and 2-allyl-2-isopropylacetamide in rat liver in vivo and in vitro. Involvement of non-carbon monoxide-forming mechanisms

1979 • 34 citations

Carbon tetrachloride-induced changes in mixed function oxidases and microsomal cytochromes in the rat lung.

1977 • 22 citations