Thrombotic Thrombocytopenic Purpura and Related Disorders

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

The Association Between Idiopathic Hemolytic Uremic Syndrome and Infection by Verotoxin-Producing Escherichia coli

1985 • 1,411 citations

Vero response to a cytotoxin of Escherichia coli

1977 • 1,182 citations

Unusually Large Plasma Factor VIII: von Willebrand Factor Multimers in Chronic Relapsing Thrombotic Thrombocytopenic Purpura

1982 • 1,105 citations

THROMBOTIC THROMBOCYTOPENIC PURPURA

1966 • 905 citations

Microangiopathic Haemolytic Anaemia: The Possible Role of Vascular Lesions in Pathogenesis

1962 • 525 citations

AN ACUTE FEBRILE PLEIOCHROMIC ANEMIA WITH HYALINE THROMBOSIS OF THE TERMINAL ARTERIOLES AND CAPILLARIES

1925 • 523 citations

Platelets have more than one binding site for von Willebrand factor.

1983 • 459 citations

UNSTABLE METABOLITES OF ARACHIDONIC ACID AND THEIR ROLE IN HAEMOSTASIS AND THROMBOSIS

1978 • 447 citations

Detection and partial characterization of an inhibitor of plasminogen activator in human platelets.

1984 • 365 citations

Nephrotoxicity of Cyclosporin a after Allogeneic Marrow Transplantation

1981 • 364 citations

Treatment of Thrombotic Thrombocytopenic Purpura with Plasma

1977 • 362 citations

Hemolytic-Uremic Syndrome after Shigellosis

1978 • 351 citations

Cyclosporin-induced endothelial cell injury.

1986 • 331 citations

Thrombosis and haemostasis

1988 • 327 citations

Thrombotic Thrombocytopenic Purpura

1981 • 319 citations

HqMOLYTIC-URqMIC SYNDROME: DEFICIENCY OF PLASMA FACTOR(S) REGULATING PROSTACYCLIN ACTIVITY?

1978 • 294 citations

The Hemolytic-Uremic Syndrome

1973 • 269 citations

HUS and TTP: Variable expression of a single entity

1987 • 261 citations

Intravascular Hemolysis, Thrombocytopenia and Other Hematologic Abnormalities Associated with Severe Toxemia of Pregnancy

1954 • 254 citations

Prostacyclin production during pregnancy: Comparison of production during normal pregnancy and pregnancy complicated by hypertension

1982 • 234 citations

Lipopolysaccharide-mediated bovine endothelial cell injury in vitro.

1983 • 215 citations

Hemolytic Uremic Syndrome in Families

1975 • 201 citations

Characterization of monoclonal antibodies against Shiga-like toxin from Escherichia coli

1985 • 198 citations

Thrombotic Microangiopathic Haemolytic Anaemia

1952 • 197 citations

Thrombin-induced exposure and prostacyclin inhibition of the receptor for factor VIII/von Willebrand factor on human platelets.

1982 • 190 citations

LYTIC ANTI-ENDOTHELIAL CELL ANTIBODIES IN HAEMOLYTIC-URAEMIC SYNDROME

1988 • 169 citations

Protein-C: biochemistry, physiology, and clinical implications

1983 • 169 citations

Presence of a platelet aggregating factor in the plasma of patients with thrombotic thrombocytopenic purpura (TTP) and its inhibition by normal plasma

1979 • 152 citations

THE EFFECTS OF ENDOTOXIN ON VASCULAR ENDOTHELIUM

1969 • 151 citations

Disseminated arteriolar and capillary platelet thrombosis; a morphologic study of its histogenesis.

1950 • 140 citations

Exchange transfusions in the treatment of thrombotic thrombocytopenic purpura.

1976 • 139 citations

UNUSUAL REMISSION IN A CASE OF THROMBOTIC THROMBOCYTOPENIC PURPURA SYNDROME FOLLOWING FRESH BLOOD EXCHANGE TRANSFUSIONS

1959 • 136 citations

Thrombotic thrombocytopenic purpura: a ten-year experience

1980 • 134 citations

Neurological involvement in hemolytic‐uremic syndrome

1986 • 132 citations

Plasma infusion for hemolytic-uremic syndrome in children: Results of a multicenter controlled trial

1988 • 129 citations

Progress in Hemostasis and Thrombosis.

1983 • 124 citations

Ineffectiveness of Aspirin and Dipyridamole in the Treatment of Thrombotic Thrombocytopenic Purpura

1982 • 120 citations

Abnormal VIII: von Willebrand factor patterns in the plasma of patients with the hemolytic-uremic syndrome

1984 • 117 citations

Hemostasis, prostaglandins, and renal disease

1980 • 114 citations

ACCELERATED PROSTACYCLIN DEGRADATION IN THROMBOTIC THROMBOCYTOPENIC PURPURA

1981 • 107 citations

Deleterious effects of platelet transfusions and recovery thrombocytosis in patients with thrombotic microangiopathy.

1987 • 106 citations

Thrombotic Thrombocytopenic Purpura and Systemic Lupus Erythematosus

1964 • 100 citations

Therapy of Thrombotic Thrombocytopenic Purpura: An Overview

1981 • 100 citations

Morphology of thrombotic thrombocytopenic purpura with demonstration of aneurysms.

1952 • 99 citations

Immunologic and Other Factors in Thrombotic Thrombocytopenic Purpura (TTP)

1980 • 98 citations

Isolation of a Microtatobiote from Patients with Hemolytic-Uremic Syndrome and Thrombotic Thrombocytopenic Purpura and from Mites in the United States

1969 • 97 citations

Treatment of Thrombotic Thrombocytopenic Purpura With Vincristine

1982 • 96 citations

Therapy of chronic relapsing thrombotic thrombocytopenic purpura with prednisone and azathioprine

1985 • 95 citations

Inhibition of platelet-aggregating activity in thrombotic thrombocytopenic purpura plasma by normal adult immunoglobulin G.

1984 • 94 citations

Cyclosporine-associated renal arteriopathy resulting in loss of allograft function

1985 • 93 citations

Novel platelet-agglutinating protein from a thrombotic thrombocytopenic purpura plasma.

1985 • 91 citations

Colonic Biopsy in Verotoxin-lnduced Hemorrhagic Colitis and Thrombotic Thrombocytopenic Purpura (TTP)

1986 • 90 citations

Thrombotic Thrombocytopenic Purpura— Coagulation Parameters in Twelve Patients

1973 • 88 citations

The hemolytic-uremic syndrome: a study of renal pathologic alterations.

1969 • 88 citations

Serum prostacyclin binding defects in thrombotic thrombocytopenic purpura.

1985 • 84 citations

Treatment of the hemolytic uremic syndrome with plasma.

1979 • 83 citations

Effects of lipopolysaccharide on human endothelial cells in culture

1983 • 82 citations

Thrombotic Thrombocytopenic Purpura: Analysis of 48 Unselected Cases

1980 • 81 citations

Impairment of platelet aggregation in hemolytic uremic syndrome: evidence for platelet "exhaustion"

1982 • 78 citations

Haemolytic uraemic syndrome: therapeutic effect of plasma infusion.

1982 • 77 citations

HÆMOLYTIC URÆMIC SYNDROME IN WOMEN TAKING ORAL CONTRACEPTIVES

1973 • 77 citations

Endotoxin-mediated pulmonary endothelial cell injury.

1986 • 75 citations

Thrombotic Thrombocytopenic Purpura

1979 • 72 citations

Gastrointestinal Disease in the Hemolytic-Uremic Syndrome

1979 • 72 citations

Thrombotic Thrombocytopenic Purpura: A Thirty Year Review

1980 • 71 citations

THROMBOTIC THROMBOCYTOPENIC PURPURA

1960 • 71 citations

Abnormalities of factor VIII related protein multimers in the haemolytic uraemic syndrome.

1984 • 71 citations

Thrombotic thrombocytopenic purpura and dose of plasma exchange

1979 • 68 citations

Le syndrome hémolytique et urémique de I’enfant

1967 • 68 citations

Isolation of Coxsackie Virus Group A, Type 4, from a Patient with Hemolytic-Uremic Syndrome

1965 • 66 citations

Enhanced proteolysis of plasma von Willebrand factor in thrombotic thrombocytopenic purpura and the hemolytic uremic syndrome

1989 • 66 citations

Thrombotic Thrombocytopenic Purpura Complicating Sjögren's Syndrome

1971 • 64 citations

The association of thrombotic thrombocytopenic purpura with systemic lupus erythematosus:

1974 • 63 citations

Respiratory dysfunction in thrombotic thrombocytopenic purpura

1978 • 63 citations

Thrombotic Thrombocytopenic Purpura-like Syndrome Associated With Infective Endocarditis

1977 • 63 citations

ENDOTHELIAL SURFACE CHARGE AND ITS POSSIBLE RELATIONSHIP TO THROMBOGENESIS

1976 • 62 citations

Deleterious effects of endotoxin on cultured endothelial cells: An in vitro model of vascular injury

1981 • 62 citations

An Unusual Syndrome of Hemolytic Anemia, Thrombocytopenic Purpura and Renal Disease

1957 • 61 citations

Thrombotic Thrombocytopenic Purpura

1976 • 61 citations

THE ASSOCIATION OF THROMBOTIC THROMBOCYTOPENIC PURPURA AND DISSEMINATED LUPUS ERYTHEMATOSUS: REPORT OF A CASE

1955 • 60 citations

Familial deficiency of a plasma factor stimulating vascular prostacyclin activity

1979 • 59 citations

Thrombotic Thrombocytopenic Purpura

1967 • 59 citations

Effect of dipyridamole and aspirin in thrombotic microangiopathy.

1972 • 58 citations

Mitomycin-induced hemolytic uremic kidney. An experimental model in the rat.

1985 • 58 citations

Recurrence of hemolytic uremic syndrome in renal transplant recipients.

1986 • 57 citations

Thrombotic thrombocytopenic purpura in four siblings

1975 • 56 citations

Inhibitor of prostacyclin production in sporadic haemolytic uraemic syndrome.

1983 • 56 citations

Treatment of Thrombotic Thrombocytopenic Purpura With Antiplatelet Drugs

1973 • 54 citations

Mitomycin- Induced Hemolytic-Uremic Syndrome

1983 • 54 citations

Plasma Infusion in the Treatment of Thrombotic Thrombocytopenic Purpura

1981 • 54 citations

Antiplatelet Therapy for Thrombotic Thrombocytopenic Purpura

1971 • 54 citations

Mitomycin-C Nephrotoxicity: A Clinico-Pathologic Study of 17 Cases

1985 • 53 citations

Treatment of thrombotic thrombocytopenic purpura by exchange transfusion

1977 • 53 citations

Renal Involvement in Patients with Thrombotic Thrombocytopenic Purpura

1986 • 51 citations

Thrombotic thrombocytopenic purpura

1952 • 51 citations

ENTEROVIRUSES ASSOCIATED WITH THE HEMOLYTIC-UREMIC SYNDROME

1970 • 51 citations

Thrombotic Thrombocytopenic Purpura in Childhood

1962 • 50 citations

Preliminary report: Treatment of the hemolytic-uremic syndrome with aspirin and dipyridamole

1975 • 49 citations

Haemolytic-uraemic syndrome: Epidemiological and clinical study

1974 • 49 citations

Splenectomy for Thrombotic Thrombocytopenic Purpura

1969 • 49 citations

Vitamin E treatment of haemolytic uraemic syndrome.

1984 • 47 citations

Thrombotic Thrombocytopenic Purpura: Report of a Case With Disseminated Intravascular Platelet Aggregation

1973 • 47 citations

Thrombotic thrombocytopenic purpura with acute anuric renal failure

1966 • 47 citations

Thrombotic Thrombocytopenic Purpura Fails to Respond to Fresh Frozen Plasma Infusion

1978 • 46 citations

Thrombotic thrombocytopenic purpura—Remission following splenectomy

1976 • 46 citations

Familial deficiency of prostacyclin production stimulating factor in the hemolytic uremic syndrome of childhood

1981 • 45 citations

Red cell membrane phospholipid abnormalities in the hemolytic uremic syndrome.

1981 • 45 citations

Amniotic fluid prostacyclin and thromboxane in normal, preeclamptic, and some other complicated pregnancies

1981 • 45 citations

The obfuscation of eclampsia by thrombotic thrombocytopenic purpura

1978 • 45 citations

Efficacy of several plasma components in a young boy with chronic thrombocytopenia and hemolytic anemia who responds repeatedly to normal plasma infusions

1984 • 44 citations

Thrombotic thrombocytopenic purpura after influenza vaccination.

1973 • 44 citations

Thrombotic thrombocytopenic purpura subsequent to acute myelogenous leukemia chemotherapy

1986 • 43 citations

Paediatric Nephrology

1984 • 41 citations

Thrombotic thrombocytopenic purpura

1974 • 41 citations

Thrombotic thrombocytopenic purpura: a syndrome of intravascular platelet consumption.

1976 • 41 citations

Thrombotic thrombocytopenic purpura complicating Legionnaires' disease

1982 • 38 citations

Thrombotic thrombocytopenic purpura

1952 • 37 citations

The treatment of the hemolytic-uremic syndrome with inhibitors of platelet function

1979 • 37 citations

Plasmapheresis in Thrombotic Thrombocytopenic Purpura

1980 • 35 citations

Giant Lymph Node Hyperplasia Associated with Thrombotic Thrombocytopenic Purpura.

1980 • 35 citations

Treatment of Thrombotic Thrombocytopenic Purpura with Combined Exchange Plasmapheresis and Anti-platelet Agents

1981 • 34 citations

Thrombotic Thrombocytopenic Purpura

1974 • 34 citations

Recurrent Thrombotic Thrombocytopenic Purpura After Viral Infection

1981 • 33 citations

Nonlethal hemolytic and uremic syndromes in children: an electron-microscope study of renal biopsies from six cases

1967 • 33 citations

Management of treatment failures in thrombotic thrombocytopenic purpura

1986 • 32 citations

Thrombotic thrombocytopenic purpura: Recovery after splenectomy associated with persistence of abnormally large von willebrand factor multimers

1985 • 31 citations

Nephrosclerosis Postpartum and in Women Taking Oral Contraceptives

1976 • 31 citations

Role of fibrinolysis in thrombotic thrombocytopenic purpura.

1987 • 31 citations

Platelet aggregating factor in the epidemic form of hemolytic-uremic syndrome in childhood.

1985 • 30 citations

Treatment of Thrombotic Thrombocytopenic Purpura

1986 • 29 citations

Thrombotic Thrombocytopenic Purpura (TTP) and Splenectomy

1978 • 29 citations

Case Report: Von Willebrand Factor Abnormalities and Endothelial Cell Perturbation in a Patient with Acute Thrombotic Thrombocytopenic Purpura

1986 • 29 citations

Thrombotic Thrombocytopenic Purpura — A Deficiency of Plasma Factors Regulating Platelet-Vessel-Wall Interaction?

1978 • 29 citations

Thrombotic Thrombocytopenic Purpura

1968 • 28 citations

Thrombotic thrombocytopenic purpura in a neonatal infant

1967 • 26 citations

The hemolytic-uremic syndrome in siblings: A prospective survey

1974 • 26 citations

Thrombotic Thrombocytopenic Purpura Occurring in the Puerperium

1958 • 25 citations

Familial haemolytic uraemic syndrome.

1978 • 25 citations

THROMBOTIC THROMBOCYTOPENIC PURPURA DIAGNOSED BY RANDOM LYMPH NODE BIOPSY

1956 • 25 citations

Abnormal Platelet and Vascular Prostaglandin Synthesis in an Infant with Hemolytic Uremic Syndrome

1983 • 25 citations

Hemolytic-Uremic Syndrome in Two Siblings

1967 • 24 citations

Fatal simultaneous thrombocytopenic purpura in siblings.

1969 • 24 citations

Thrombotic Thrombocytopenic Purpura

1968 • 24 citations

Thrombotic Thrombocytopenic Purpura

1983 • 21 citations

Splenectomy, Steroids, and Dextran 70 in Thrombotic Thrombocytopenic Purpura

1974 • 21 citations

Investigation of the role of von Willebrand factor in thrombotic thrombocytopenic purpura

1985 • 20 citations

Clinical Features of Thrombotic Thrombocytopenic Purpura

1980 • 20 citations

Familial Occurrence of the Haemolytic Uraemic Syndrome

1980 • 20 citations

Platelet-Inhibiting Drugs in Thrombotic Thrombocytopenic Purpura

1977 • 20 citations

Adult Hemolytic-Uremic Syndrome

1977 • 20 citations

Thrombotic thrombocytopenic purpura in siblings

1967 • 18 citations

Haemostasis and the kidney

1990 • 18 citations

Thrombotic thrombocytopenic purpura

1962 • 17 citations

PLATELET THROMBOSIS WITH POLYARTERITIS NODOSA; REPORT OF A CASE.

1964 • 17 citations

Thrombotic thrombocytopenic purpura

1980 • 16 citations

Ineffective Epoprostenol Therapy for Thrombotic Thrombocytopenic Purpura

1983 • 16 citations

Splenectomy and Antiplatelet Agents in Thrombotic Thrombocytopenic Purpura

1979 • 15 citations

Treatment of Thrombotic Thrombocytopenic Purpura With Plasma Infusions and Cyclophosphamide

1979 • 15 citations

HÆMOLYTIC-URÆMIC SYNDROME

1968 • 15 citations

Thrombotic Thrombocytopenic Purpura: Treatment with a Combination of Antiplatelet Drugs

1979 • 14 citations

Hemolytic uremic syndrome and prostatic adenocarcinoma.

1987 • 13 citations

Thrombotic thrombocytopenic purpura. Remission following treatment with aspirin and dipyridamole.

1977 • 12 citations

Reduced Platelet Aggregation in Hemolytic-Uremic Syndrome

1980 • 12 citations

Thrombotic Thrombocytopenic Purpura and Hemolytic-Uremic Syndrome in HLA-Identical Siblings

1980 • 11 citations

Syndrome Resembling Thrombotic Thrombocytopenic Purpura Associated With Bacterial Endocarditis

1980 • 11 citations

In vitro prostacyclin production in the hemolytic-uremic syndrome.

1986 • 11 citations

Case Report Thrombotic thrombocytopenic purpura in a splenectomized patient with Hodgkin’s disease

1980 • 10 citations

SIMULTANEOUS THROMBOTIC THROMBOCYTOPENIC PURPURA AND AGAMMAGLOBULINÆMIA

1960 • 10 citations

Prostacyclin production by whole blood from children : Impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure

1983 • 8 citations

The Blood Counts and Lactate Dehydrogenase Levels in Thrombotic Thrombocytopenic Purpura (TTP)

1983 • 7 citations

Thrombotic thrombocytopenic purpura successfully treated with a combination of dipyridamole and aspirin.

1980 • 6 citations

Plasma exchange as intensive therapy in thrombotic thrombocytopenic purpura.

1985 • 5 citations

Morphology of the vascular lesions in "thrombotic thrombocytopenic purpura" with demonstration of aneurysms.

1951 • 5 citations

[The hemolytic uremic syndrome in sibs].

1977 • 5 citations

Thrombotic thrombocytopenic purpura: temporary remission induced by prednisone.

1966 • 2 citations

"Platelet thromboses" involving the gastrointestinal tract: report of a case.

1953 • 2 citations