Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1995 • 3,977 citations

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

1993 • 2,370 citations

Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

1988 • 2,004 citations

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

1985 • 1,983 citations

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1993 • 1,961 citations

Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides

1988 • 1,848 citations

Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation

1992 • 1,103 citations

Hematopoietic commitment during embryonic stem cell differentiation in culture.

1993 • 919 citations

Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector

1986 • 761 citations

flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors

1993 • 707 citations

Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies

1988 • 667 citations

A novel endothelial-specific membrane protein is a marker of cell-cell contacts.

1992 • 637 citations

Erythropoietin receptor mRNA expression in human endothelial cells.

1994 • 584 citations

Erythropoietin has a mitogenic and positive chemotactic effect on endothelial cells.

1990 • 574 citations

Vascularization of the mouse embryo: A study of flk‐1, tek, tie, and vascular endothelial growth factor expression during development

1995 • 546 citations

Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system.

1993 • 470 citations

Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.

1993 • 469 citations

Pattern of interleukin 6 gene expression in vivo suggests a role for this cytokine in angiogenesis.

1990 • 350 citations

Hematopoietic development of embryonic stem cells in vitro: cytokine and receptor gene expression.

1991 • 332 citations

Molecular cloning and expression of murine vascular endothelial- cadherin in early stage development of cardiovascular system

1996 • 325 citations

Molecular and functional aspects of PECAM-1/CD31

1994 • 325 citations

Monoclonal antibodies specific for endothelial cells of mouse blood vessels. Their application in the identification of adult and embryonic endothelium.

1994 • 315 citations

Platelet endothelial cell adhesion molecule-1 (PECAM-1 / CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development

1994 • 301 citations

Expression of tie-2, a member of a novel family of receptor tyrosine kinases, in the endothelial cell lineage

1993 • 275 citations

Hematopoietic Commitment During Embryonic Stem Cell Differentiation in Culture

1993 • 273 citations

Mouse embryonic hematopoiesis

1995 • 266 citations

Recombinant human erythropoietin stimulates angiogenesis in vitro

1995 • 252 citations

The sialomucin CD34 is expressed on hematopoietic cells and blood vessels during murine development

1995 • 240 citations

Embryonic stem cell-derived cystic embryoid bodies form vascular channels: an in vitro model of blood vessel development

1992 • 239 citations

[49] Derivation of embryonic stem cell lines

1993 • 228 citations

Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood brain barrier

1995 • 214 citations

Angioblast differentiation and morphogenesis of the vascular endothelium in the mouse embryo

1991 • 181 citations

[54] Embryonic stem cell differentiation in vitro

1993 • 116 citations

Origins and Assembly of Avian Embryonic Blood Vessels^a

1990 • 108 citations

Embryonic angiogenesis factors

1991 • 103 citations

NYK/FLK-1: a putative receptor protein tyrosine kinase isolated from E10 embryonic neuroepithelium is expressed in endothelial cells of the developing embryo.

1993 • 90 citations

Molecular cloning and adhesive properties of murine platelet/endothelial cell adhesion molecule 1.

1993 • 90 citations

Mouse embryo stem cells: their identification, propagation and manipulation

1992 • 80 citations

Embryonic stem cell model systems for vascular morphogenesis and cardiac disorders.

1993 • 65 citations

tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system

1993 • 14 citations

Embryonic stem cell-derived cystic embryoid bodies form vascular channels : an in vitro model of blood vessel development

1992 • 11 citations