Oxidation-reduction states of pyridine nucleotide and cytochrome P-450 during mixed-function oxidation in perfused rat liver.

Role of Hemoprotein P-450 in Fatty Acid ω-Hydroxylation in a Soluble Enzyme System from Liver Microsomes

1968 • 625 citations

The rate of gluconeogenesis from various precursors in the perfused rat liver

1967 • 397 citations

Mechanisms of Oxygen Metabolism

1957 • 312 citations

The distribution of hepatic metabolites and the control of the pathways of carbohydrate metabolism in animals of different dietary and hormonal status

1971 • 301 citations

Flavin and Pyridine Nucleotide Oxidation-Reduction Changes in Perfused Rat Liver

1969 • 255 citations

A new spectral intermediate associated with cytochrome P-450 function in liver microsomes

1971 • 240 citations

Gradients of O2 concentration in hepatocytes.

1978 • 189 citations

Spin state control of the hepatic cytochrome P450 redox potential

1979 • 130 citations

Biochemical and Ultrastructural Evaluation of Isolated Rat Liver Systems Perfused with a Hemoglobin-Free Medium

1978 • 117 citations

Heterogeneity of liver microsomal cytochrome P-450: The spectral characterization of reactants with reduced cytochrome P-450

1975 • 103 citations

A Study of Drug Metabolism Linked to Cytochrome P‐450 in Isolated Rat‐Liver Cells

1974 • 103 citations

The Disposition of Formaldehyde and Formate Arising from Drug N-Demethylations Dependent on Cytochrome P-450 in Hepatocytes and in Perfused Rat Liver

1978 • 80 citations

Interaction of Mixed Function Oxidase with its Substrates and Associated Redox Transitions of Cytochrome P‐450 and Pyridine Nucleotides in Perfused Rat Liver

1970 • 74 citations

Studies on the microsomal mixed function oxidase system: redox properties of detergent-solubilized NADPH-cytochrome P-450 reductase

1978 • 73 citations

Rate-Limiting Step in the Reconstituted Microsomal Drug Hydroxylase System1

1977 • 61 citations

Interactions between ethanol metabolism and mixed-function oxidation in perfused rat liver: inhibition of p-nitroanisole O-demethylation.

1980 • 56 citations

Microfluorometry of oxidation-reduction state of the rat kidney in situ.

1971 • 56 citations

The continuous kinetic determination of p-nitroanisole O-demethylation in hemoglobin-free perfused rat liver.

1977 • 52 citations

Mixed function oxidation of hexobarbital and generation of NADPH by the hexose monophosphate shunt in isolated rat liver cells

1975 • 40 citations

Hemoprotein quantitation in isolated hepatocytes

1979 • 39 citations

Hepatic organelle interaction. I. Spectral investigation during drug biotransformation.

1972 • 37 citations

Inhibition of mixed-function oxidation of p-nitroanisole in perfused rat liver by 2,4-dinitrophenol

1980 • 18 citations

Stimulation of p-nitroanisole O-demethylation in perfused livers by xylitol and sorbitol

1980 • 18 citations

Oxidation-reduction state of free NADP+ during mixed-function oxidation in perfused rat livers—Evaluation of the assumptions of near equilibrium by comparisons of surface fluorescence changes and calculated NADP+:NADPH ratios

1979 • 11 citations