Replication-dependent transactivation of the polyomavirus late promoter

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

Die Molekularbiologie der Tumorviren

1977 • 951 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides.

1975 • 616 citations

The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element

1983 • 467 citations

Coding potential and regulatory signals of the polyoma virus genome

1980 • 369 citations

A region of the polyoma virus genome between the replication origin and late protein coding sequences is required in cis for both early gene expression and viral DNA replication

1981 • 304 citations

Activation of the SV40 late promoter: Direct effects of T antigen in the absence of viral DNA replication

1984 • 292 citations

Polyoma virus DNA replication requires an enhancer

1984 • 253 citations

Stimulation of simian virus 40 late gene expression by simian virus 40 tumor antigen.

1984 • 207 citations

Polyomavirus enhancer contains multiple redundant sequence elements that activate both DNA replication and gene expression.

1985 • 206 citations

Origin-defective Mutants of SV40

1980 • 193 citations

Assembly of transfected DNA into chromatin: structural changes in the origin-promoter-enhancer region upon replication.

1984 • 178 citations

Transcriptional ‘enhancers’ from SV40 and polyoma virus show a cell type preference

1982 • 177 citations

Transient gene expression control: effects of transfected DNA stability and trans-activation by viral early proteins.

1985 • 174 citations

Localization of gene functions in polyoma virus DNA.

1976 • 154 citations

Polyomavirus origin for DNA replication comprises multiple genetic elements

1983 • 132 citations

The Adenine-Thymine Domain of the Simian Virus 40 Core Origin Directs DNA Bending and Coordinately Regulates DNA Replication

1986 • 130 citations

Multiple binding sites for polyomavirus large T antigen within regulatory sequences of polyomavirus DNA

1984 • 121 citations

trans Activation of the Simian Virus 40 Late Transcription Unit by T-Antigen

1985 • 118 citations

Analysis of an activatable promoter: sequences in the simian virus 40 late promoter required for T-antigen-mediated trans activation.

1985 • 115 citations

Non-contiguous segments of the polyoma genome required in cis for DNA replication

1982 • 108 citations

Multiple 5′ terminal cap structures in late polyoma virus RNA

1979 • 105 citations

The high affinity binding site on polyoma virus DNA for the viral large-T protein

1981 • 91 citations

Sequences in the polyomavirus DNA regulatory region involved in viral DNA replication and early gene expression

1985 • 83 citations

Sequences at the capped 5′-ends of polyoma virus late region mRNAs: an example of extreme terminal heterogeneity

1981 • 76 citations

An enhancer sequence from bovine papilloma virus DNA consists of two essential regions

1984 • 72 citations

Analysis of an Activatable Promoter: Sequences in the Simian Virus 40 Late Promoter Required for T-Antigen-Mediated trans Activation

1985 • 67 citations

The simian virus 40 minimal origin and the 72-base-pair repeat are required simultaneously for efficient induction of late gene expression with large tumor antigen.

1984 • 64 citations

Transient Gene Expression Control: Effects of Transfected DNA Stability and trans-Activation by Viral Early Proteins

1985 • 62 citations

Polyomavirus large T antigen binds independently to multiple, unique regions on the viral genome

1983 • 62 citations

Regulation of polyomavirus transcription by large tumor antigen.

1984 • 60 citations

DNA Sequence Requirements for Replication of Polyomavirus DNA In Vivo and In Vitro

1987 • 54 citations

Localization of Three Major Capped 5′ Ends of Polyoma Virus Late mRNA's Within a Single Tetranucleotide Sequence in the Viral Genome

1980 • 53 citations

The origin of bidirectional DNA replication in polyoma virus.

1987 • 52 citations

Polyomavirus tumor induction in mice: influences of viral coding and noncoding sequences on tumor profiles

1987 • 50 citations

Location of sequences in polyomavirus DNA that are required for early gene expression in vivo and in vitro.

1984 • 49 citations

DNA replication origin of polyoma virus: early proximal boundary

1983 • 48 citations

Multiple subelements within the polyomavirus enhancer function synergistically to activate DNA replication.

1988 • 47 citations

Polyomavirus early-late switch is not regulated at the level of transcription initiation and is associated with changes in RNA processing.

1988 • 46 citations

Regulation of polyomavirus late promoter activity by viral early proteins

1986 • 45 citations

Essential nucleotides in the polyomavirus origin region

1984 • 43 citations

The polyomavirus enhancer comprises multiple functional elements

1988 • 39 citations

Multiple Subelements within the Polyomavirus Enhancer Function Synergistically To Activate DNA Replication

1988 • 34 citations

Location of Sequences in Polyomavirus DNA That Are Required for Early Gene Expression In Vivo and In Vitro

1984 • 33 citations

Deletion analysis of the polyomavirus late promoter: evidence for both positive and negative elements in the absence of early proteins

1989 • 33 citations

Deletion mutants of polyoma virus defining a nonessential region between the origin of replication and the initiation codon for early proteins

1979 • 31 citations

Transcription from the polyoma late promoter in cells stably transformed by chimeric plasmids.

1985 • 31 citations

Polyoma virus early and late mRNAs in productively infected mouse 3T6 cells

1982 • 31 citations

Cell- and promoter-specific activation of transcription by DNA replication.

1987 • 25 citations

Common regulatory elements control gene expression from polyoma early and late promoters in cells transformed by chimeric plasmids.

1985 • 24 citations

Polyomavirus late leader region serves an essential spacer function necessary for viability and late gene expression

1986 • 24 citations

Control elements situated downstream of the major transcriptional start site are sufficient for highly efficient polyomavirus late transcription

1989 • 23 citations

Common Regulatory Elements Control Gene Expression from Polyoma Early and Late Promoters in Cells Transformed by Chimeric Plasmids

1985 • 21 citations

Transcription from the Polyoma Late Promoter in Cells Stably Transformed by Chimeric Plasmids

1985 • 21 citations

Polyoma virus DNA replication is semi-discontinuous

1987 • 16 citations

Comeasurement of simian virus 40 early and late promoter activity in HeLa and 293 cells in the presence of T antigen

1989 • 14 citations

Inhibition of polyoma DNA synthesis by base pair substitutions at the replication origin

1984 • 14 citations

A nonlethal mutation in large T antigen of polyomavirus which affects viral DNA synthesis

1989 • 5 citations