Fascin, a sensitive new marker for Reed-Sternberg cells of hodgkin's disease. Evidence for a dendritic or B cell derivation?

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

1984 • 3,268 citations

The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells

1985 • 1,817 citations

Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development.

1994 • 691 citations

The distinct surface of human blood dendritic cells, as observed after an improved isolation method.

1990 • 402 citations

Impaired Lymphocyte Function in Untreated Hodgkin's Disease

1974 • 294 citations

Criteria for involvement of lymph node, bone marrow, spleen, and liver in Hodgkin's disease.

1971 • 277 citations

“sternberg‐reed” giant cells of hodgkin's disease: Cultivation in vitro, heterotransplantation, and characterization as neoplastic macrophages

1977 • 202 citations

Hodgkin's Disease with Monoclonal and Polyclonal Populations of Reed–Sternberg Cells

1995 • 200 citations

Phenotypic expression of Hodgkin's and Reed-Sternberg cells in Hodgkin's disease.

1985 • 196 citations

Monoclonal Antibodies in the Diagnosis of Hodgkinʼs Disease

1988 • 196 citations

Exogenous Immunoglobulin and the Macrophage Origin of Reed–Sternberg Cells in Hodgkin's Disease

1978 • 180 citations

In situ immunologic characterization of cellular constituents in lymph nodes and spleens involved by Hodgkin's disease

1982 • 169 citations

Expression of B-cell antigens by Hodgkin's and Reed-Sternberg cells.

1991 • 163 citations

Hodgkin's disease, lymphocyte predominance type, nodular--further evidence for a B cell derivation. L & H variants of Reed-Sternberg cells express L26, a pan B cell marker.

1988 • 156 citations

Leu-M1--a marker for Reed-Sternberg cells in Hodgkin's disease. An immunoperoxidase study of paraffin-embedded tissues.

1985 • 156 citations

Circulating human dendritic cells differentially express high levels of a 55-kd actin-bundling protein.

1996 • 155 citations

Hodgkin's disease, lymphocyte predominance type, nodular--a distinct entity? Unique staining profile for L&H variants of Reed-Sternberg cells defined by monoclonal antibodies to leukocyte common antigen, granulocyte-specific antigen, and B-cell-specific antigen.

1985 • 139 citations

Intracellular localization of the 55-kD actin-bundling protein in cultured cells: spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin.

1986 • 128 citations

The immunophenotype of reed-sternberg cells. A study of 50 cases of Hodgkin' disease using fixed frozen tissues

1989 • 126 citations

Purification and characterization of an F-actin-bundling 55-kilodalton protein from HeLa cells.

1985 • 124 citations

Hodgkin's disease with a B-cell phenotype often shows a VDJ rearrangement and somatic mutations in the VH genes

1994 • 120 citations

Epstein-Barr virus infection induces expression in B lymphocytes of a novel gene encoding an evolutionarily conserved 55-kilodalton actin-bundling protein

1994 • 105 citations

Possible origin of the Reed-Sternberg cell from an interdigitating reticulum cell.

1982 • 105 citations

Manifestations of immunologic unresponsiveness in Hodgkin's disease.

1966 • 101 citations

Morphologic, immunologic, enzymehistochemical and chromosomal analysis of a cell line derived from Hodgkin's disease. Evidence for a B-cell origin of sternberg-reed cells

1985 • 93 citations

Rosetting and other reactions of the Reed‐Sternberg cell

1977 • 88 citations

Immunophenotypes of Reed-Sternberg cells: a study of 19 cases of Hodgkin's disease in plastic-embedded sections

1989 • 84 citations

cDNA Cloning and Expression of the Human Homolog of the Sea UrchinfascinandDrosophila singedGenes Which Encodes an Actin-Bundling Protein

1994 • 79 citations

Detection of immunoglobulin heavy‐chain gene rearrangement at the single‐cell level in malignant lymphomas: No rearrangement is found in hodgkin and reed‐sternberg cells

1994 • 76 citations

Leu 7 (CD57) reactivity distinguishes nodular lymphocyte predominance Hodgkin's disease from nodular sclerosing Hodgkin's disease, T-cell-rich B-cell lymphoma and follicular lymphoma.

1993 • 74 citations

CD40 expression in Hodgkin's disease.

1994 • 70 citations

Absence of bcl-2 major breakpoint region and JH gene rearrangement in lymphocyte predominance Hodgkin's disease. Results of Southern blot analysis and polymerase chain reaction.

1991 • 66 citations

Expression of interleukin-1 in Reed-Sternberg cells and neoplastic cells from true histiocytic malignancies.

1986 • 64 citations

The expression of the B‐cell marker mb‐1 (CD79a) in Hodgkin's disease

1994 • 63 citations

Neoplastic cells obtained from Hodgkin's disease are potent stimulators of human primary mixed lymphocyte cultures.

1983 • 63 citations

Is the Hodgkin cell A T‐ or B‐lymphocyte? recent evidence from geno‐ and immunophenotypic analysis and in‐vitro cell lines

1989 • 55 citations

Relation of follicular dendritic reticulum cells to Reed-Sternberg cells of Hodgkin's disease with emphasis on the expression of CD21 antigen.

1993 • 52 citations

Absence of t(14;18) major and minor breakpoints and of Bcl-2 protein overproduction in Reed-Sternberg cells of Hodgkin's disease.

1991 • 52 citations

Demonstration of light chain mRNA in Hodgkin's disease

1993 • 48 citations

POSSIBLE T-LYMPHOCYTE ORIGIN OF REED-STERNBERG CELLS

1974 • 47 citations

Aberrant expression of T cell and B cell markers in myelocyte/monocyte/histiocyte-derived lymphoma and leukemia cells. Is the infrequent expression of T/B cell markers sufficient to establish a lymphoid origin for Hodgkin's Reed-Sternberg cells?

1989 • 47 citations

Macrophage origin of Reed-Sternberg cells: an immunohistochemical study

1982 • 46 citations

Immunohistochemical detection of Epstein-Barr virus-encoded latent membrane protein in Reed-Sternberg cells and variants of Hodgkin's disease.

1994 • 43 citations

The Reed-Sternberg cell/lymphocyte interaction: ultrastructure and characteristics of binding.

1980 • 38 citations

Molecular biologic studies of Hodgkin's disease.

1992 • 35 citations

Immunopathology of Hodgkin's disease. Characterization of Reed-Sternberg cells with monoclonal antibodies.

1986 • 34 citations

Nodular sclerosing, mixed cellularity and lymphocyte-depleted variants of Hodgkin's disease are probable dendritic cell malignancies.

1989 • 32 citations

The bcl-2 gene translocation is undetectable in Hodgkin's disease by Southern blot hybridization and polymerase chain reaction.

1992 • 29 citations

Histochemistry of Hodgkin's disease.

1982 • 28 citations

Biochemical and Ultrastructural Study of Leu M1 Antigen in Reed-Sternberg Cells: Comparison With Granulocytes and Interdigitating Reticulum Cells

1986 • 28 citations

Cultured Reed-Sternberg cells HDLM-1 and KM-H2 can be induced to become histiocytelike cells. H-RS cells are not derived from lymphocytes.

1990 • 25 citations

Extracellular matrix does not induce the proliferation, but promotes the differentiation, of Hodgkin's cell line HDLM-1.

1987 • 22 citations

The nature of the hodgkin cell

1988 • 22 citations

Expression of prostaglandin H synthase (cyclooxygenase) in Hodgkin's mononuclear and Reed-Sternberg cells. Functional resemblance between H-RS cells and histiocytes or interdigitating reticulum cells.

1988 • 21 citations

Identification of an Mr 70,000 antigen associated with Reed-Sternberg cells and interdigitating reticulum cells.

1990 • 18 citations

Hodgkin's disease revisited: Reed-Sternberg cells as natural hybridomas.

1991 • 13 citations

The never-ending controversies in Hodgkin's disease [letter; comment] [see comments]

1990 • 8 citations