Molecular structures of glycoprotein hormones and functions of their carbohydrate components
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Abstract
References (231)
Two distinct classes of carbohydrate-recognition domains in animal lectins.
1988 • 1,259 citations
Lutropin-Choriogonadotropin Receptor: An Unusual Member of the G Protein-Coupled Receptor Family
1989 • 955 citations
ASSAY OF THE FOLLICLE STIMULATING HORMONE BASED ON THE AUGMENTATION WITH HUMAN CHORIONIC GONADOTROPIN
1953 • 696 citations
The Role of Polyprenol-Linked Sugars in Glycoprotein Synthesis
1976 • 680 citations
TOPOGRAPHY OF GLYCOSYLATION IN THE ROUGH ENDOPLASMIC RETICULUM AND GOLGI APPARATUS
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Characterization of Several Clonal Lines of Cultured Ley dig Tumor Cells: Gonadotropin Receptors and Steroidogenic Responses*
1981 • 596 citations
[17] Hydrazinolysis of asparagine-linked sugar chains to produce free oligosaccharides
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THE BIOASSAY OF THYROTROPIN IN SERUM1
1958 • 429 citations
Glycoproteins
1970 • 408 citations
AN IMPROVED IN VITRO BIOASSAY METHOD FOR MEASURING LUTEINIZING HORMONE (LH) ACTIVITY USING MOUSE LEYDIG CELL PREPARATIONS
1974 • 385 citations
[6] Analysis of oligosaccharides by gel filtration
1982 • 350 citations
Asparagine-linked oligosaccharides on lutropin, follitropin, and thyrotropin. I. Structural elucidation of the sulfated and sialylated oligosaccharides on bovine, ovine, and human pituitary glycoprotein hormones.
1988 • 344 citations
F.A.B.-Mass Spectrometry of Carbohydrates
1987 • 340 citations
Evolution of the genes for the β subunits of human chorionic gonadotropin and luteinizing hormone
1984 • 336 citations
The synthesis of complex-type oligosaccharides. II. Characterization of the processing intermediates in the synthesis of the complex oligosaccharide units of the vesicular stomatitis virus G protein
1978 • 335 citations
Pituitary glycoprotein hormone oligosaccharides: Structure, synthesis and function of the asparagine-linked oligosaccharides on lutropin, follitropin and thyrotropin
1988 • 302 citations
Isolation, cloning and sequence analysis of the cDNA for the α-subunit of human chorionic gonadotropin
1979 • 298 citations
The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta subunit.
1975 • 292 citations
The cDNA for the β-subunit of human chorionic gonadotropin suggests evolution of a gene by readthrough into the 3′-untranslated region
1980 • 271 citations
A HIGHLY SENSITIVE IN VITRO BIOASSAY FOR LUTEINIZING HORMONE AND CHORIONIC GONADOTROPIN: TESTOSTERONE PRODUCTION BY DISPERSED LEYDIG CELLS.
1974 • 265 citations
Role of carbohydrate of human chorionic gonadotropin in the mechanism of hormone action
1975 • 251 citations
Structures of N-glycosidic carbohydrate units of human chorionic gonadotropin.
1979 • 242 citations
Human Chorionic Gonadotropin
1973 • 226 citations
Site specificity of the chorionic gonadotropin N-linked oligosaccharides in signal transduction
1989 • 225 citations
A Role for Glycosylation of the α Subunit in Transduction of Biological Signal in Glycoprotein Hormones
1985 • 222 citations
Evolution of Gonadotropin Structure and Function
1977 • 216 citations
[18] Lectin affinity chromatography of glycopeptides
1987 • 215 citations
Structure and location of the O-glycosidic carbohydrate units of human chorionic gonadotropin.
1979 • 215 citations
The glycoprotein hormones: recent studies of structure‐function relationships
1988 • 214 citations
The role of the asparagine-linked oligosaccharides of the alpha subunit in the secretion and assembly of human chorionic gonadotrophin.
1988 • 203 citations
Conformational restrictions on the pathway of folding and unfolding of the pancreatic trypsin inhibitor
1977 • 188 citations
The Biological Role of the Carboxyl-Terminal Extension of Human Chorionic Gonadotroin β-Subunit
1990 • 187 citations
InVitroBioassay of LH in Human Serum: The Rat Interstitial Cell Testosterone (RICT) Assay
1976 • 177 citations
Thyroid-Stimulating Hormone: Biosynthesis, Cell Biology, and Bioactivity
1990 • 175 citations
alpha Subunit of rat pituitary glycoprotein hormones. Primary structure of the precursor determined from the nucleotide sequence of cloned cDNAs.
1982 • 160 citations
Structure–Function Relationships of Gonadotropins
1987 • 158 citations
Structures of the asparagine-linked sugar chains of human chorionic gonadotropin produced in choriocarcinoma. Appearance of triantennary sugar chains and unique biantennary sugar chains.
1983 • 154 citations
Immunological and Biological Activity of HCG Following Progressive Desialylation
1971 • 150 citations
Structural elucidation of the disulfated oligosaccharide from bovine lutropin.
1985 • 148 citations
The Primary Structure of Bovine Thyrotropin
1971 • 141 citations
The Binding of Desialylated Glycoproteins by Plasma Membranes of Rat Liver
1972 • 138 citations
Studies on the Structure of Thyrotropin: Its Relationship to Luteinizing Hormone
1971 • 138 citations
DNA Sequence and Regional Assignment of the Human Follicle-Stimulating Hormone β-Subunit Gene to the Short Arm of Human Chromosome 11
1987 • 131 citations
Chromosome assignment of genes encoding the? and? subunits of glycoprotein hormones in man and mouse
1983 • 128 citations
Use of monoclonal antibodies to subunits of human chorionic gonadotropin to examine the orientation of the hormone in its complex with receptor.
1982 • 125 citations
Oligosaccharide moieties of glycoprotein hormones: bovine lutropin resists enzymatic deglycosylation because of terminal O-sulfated N-acetylhexosamines.
1980 • 122 citations
Conformational transitions in N-linked oligosaccharides
1986 • 120 citations
Solution conformation of .alpha.-D-(1-3)- and .alpha.-D-(1-6)-linked oligomannosides using proton nuclear magnetic resonance
1983 • 120 citations
A map of the hCG beta-LH beta gene cluster.
1986 • 118 citations
The β-subunit of follicle-stimulating hormone is deleted in patients with aniridia and Wilms' tumour, allowing a further definition of the WAGR locus
1986 • 118 citations
The Heterogeneity of Human Chorionic Gonadotropin (hCG). III. The Occurrence and Biological and Immunological Activities of Nicked hCG*
1991 • 118 citations
Human Follicle-Stimulating Hormone β-Subunit Gene Encodes Multiple Messenger Ribonucleic Acids
1988 • 116 citations
Structures of the Asparagine-Linked Sugar Chains of Human Chorionic Gonadotropin
1980 • 115 citations
Rapid separation of anionic oligosaccharide species by high performance liquid chromatography
1981 • 111 citations
The Primary Structure of Ovine Luteinizing Hormone
1972 • 110 citations
Granulosa Cell Aromatase Bioassay for Follicle-Stimulating Hormone: Validation and Application of the Method*
1986 • 108 citations
Isolation and characterization of the human thyrotropin beta-subunit gene. Differences in gene structure and promoter function from murine species.
1988 • 106 citations
A new force‐field program for the calculation of glycopeptides and its application to a heptacosapeptide‐decasaccharide of immunoglobulin G1
1990 • 106 citations
THE PRIMARY STRUCTURE OF THE HORMONE-SPECIFIC, BETA SUBUNIT OF HUMAN PITUITARY LUTEINIZING HORMONE (hLH)
1973 • 102 citations
Purification of an alternate form of the alpha subunit of the glycoprotein hormones from bovine pituitaries and identification of its O-linked oligosaccharide.
1983 • 100 citations
Human chorionic gonadotropin: A proposal for the amino acid sequence
1973 • 99 citations
Isolation and structure determination of the intact sialylated N‐linked carbohydrate chains of recombinant human follitropin expressed in Chinese hamster ovary cells
1990 • 98 citations
The sialylated oligosaccharides of recombinant bovine lutropin modulate hormone bioactivity.
1990 • 97 citations
Effects of Progressive Desialylation on the Rate of Disappearance of Immunoreactive HCG from Plasma in Rats
1971 • 96 citations
Nucleotide sequence of the mRNA encoding the pre-alpha-subunit of mouse thyrotropin.
1981 • 96 citations
The Primary Structure of Ovine Luteinizing Hormone
1972 • 95 citations
Nucleotide sequence of the cDNA encoding the precursor of the beta subunit of rat lutropin.
1983 • 95 citations
Molecular cloning of the human thyrotropin‐β subunit gene
1985 • 93 citations
Free alpha molecules from pregnancy stimulate secretion of prolactin from human decidual cells: a novel function for free alpha in pregnancy.
1991 • 92 citations
Amino acid sequence of the beta subunit of follicle-stimulating hormone from human pituitary glands.
1976 • 91 citations
NMR investigations of the N‐linked oligosaccharides at individual glycosylation sites of human lutropin
1991 • 91 citations
A SENSITIVE AND SPECIFIC IN VITRO BIOASSAY METHOD FOR THE MEASUREMENT OF FOLLICLE-STIMULATING HORMONE ACTIVITY
1979 • 90 citations
Glycosylation of Thyroid-Stimulating Hormone in Pituitary Tumor Cells: Influence of High Mannose Oligosaccharide Units on Subunit Aggregation, Combination, and Intracellular Degradation
1983 • 89 citations
Different asparagine-linked sugar chains on the two polypeptide chains of human chorionic gonadotropin
1980 • 87 citations
Comparisons between the α Chain of Bovine Thyrotropin and the CI Chain of Luteinizing Hormone
1971 • 85 citations
The gene for the beta subunit of bovine luteinizing hormone encodes a gonadotropin mRNA with an unusually short 5'-untranslated region.
1985 • 84 citations
The Antigenic Surface of Human Chorionic Gonadotropin as Mapped by Murine Monclonal Antibodies*
1986 • 83 citations
Comparative study of the mucin-type sugar chains of human chorionic gonadotropin present in the urine of patients with trophoblastic diseases and healthy pregnant women.
1988 • 82 citations
Structural studies on equine glycoprotein hormones. Amino acid sequence of equine chorionic gonadotropin beta-subunit.
1987 • 80 citations
A synthetic peptide corresponding to human FSH beta-subunit 33-53 binds to FSH receptor, stimulates basal estradiol biosynthesis, and is a partial antagonist of FSH
1990 • 79 citations
Size fractionation of anionic oligosaccharides and glycopeptides by high-performance liquid chromatography
1983 • 79 citations
Identification of a follicle-stimulating hormone receptor-binding region in hFSH-beta-(81-95) using synthetic peptides.
1990 • 77 citations
Molecular cloning and sequencing of salmon gonadotropin β subunit
1986 • 77 citations
HUMAN FOLLICLE STIMULATING HORMONE: FIRST PROPOSAL FOR THE AMINO ACID SEQUENCE OF THE HORMONE-SPECIFIC, β SUBUNIT (hFSHβ)
1974 • 77 citations
Combination of rat lutropin subunits occurs early in the secretory pathway.
1982 • 76 citations
Site-specific N-glycosylation of human chorionic gonadotrophin—structural analysis of glycopeptides by one- and two-dimensional1H NMR spectroscopy
1991 • 76 citations
Inhibition of adenylyl cyclase activity in rat corpora luteal tissue by glycopeptides of human chorionic gonadotropin and the .alpha.-subunit of human chorionic gonadotropin
1985 • 75 citations
Cloning of cDNA encoding the pre-beta subunit of mouse thyrotropin.
1983 • 74 citations
Tertiary structure in N-linked oligosaccharides
1987 • 74 citations
Molecular Cloning and Nucleotide Sequence Analysis of Complementary Deoxyribonucleic Acid for the β-Subunit of Rat Follicle Stimulating Hormone
1987 • 73 citations
Antigenic Features of Human Follicle Stimulating Hormone Delineated by Monoclonal Antibodies and Construction of an Immunoradiomometric Assay
1988 • 73 citations
Thyroid-stimulating hormone subunit processing and combination in microsomal subfractions of mouse pituitary tumor.
1982 • 72 citations
Fundulus heteroclitus gonadotropins. 3. Cloning and sequencing of gonadotropic hormone (GTH) I and II β-subunits using the polymerase chain reaction
1992 • 71 citations
Assignment of disulfide bonds in the beta subunit of human chorionic gonadotropin.
1981 • 71 citations
The complete amino acid sequences of β-subunits of two distinc chum salmon GTHs
1988 • 70 citations
Differential processing of Asn-linked oligosaccharides on pituitary glycoprotein hormones: implications for biologic function
1986 • 70 citations
Thyroid Hormone Decreases Thyrotropin Subunit mRNA Levels in Rat Anterior Pituitary
1984 • 68 citations
Biologically active covalently cross-linked glycoprotein hormones and the effects of modification of the COOH-terminal region of their alpha subunits.
1979 • 67 citations
Structural studies on equine glycoprotein hormones. Amino acid sequence of equine lutropin beta-subunit.
1987 • 65 citations
Assignment of disulfide bonds in the alpha subunit of human chorionic gonadotropin.
1980 • 64 citations
Isolation and Characterization of the Gene Encoding the β-Subunit of Rat Follicle-Stimulating Hormone
1989 • 64 citations
Crystallization and characterization of human chorionic gonadotropin in chemically deglycosylated and enzymically desialylated states
1989 • 63 citations
Structure of the Lutropin/Choriogonadotropin Receptor
1990 • 63 citations
The sequence of a cloned cDNA for the beta subunit of bovine thyrotropin predicts a protein containing both NH2-and COOH-terminal extensions.
1984 • 63 citations
Luteinizing Hormone
1973 • 62 citations
The primary structure of ovine interstitial cell-stimulating hormone
1972 • 61 citations
Sialic acid moiety is responsible for the charge heterogeneity and the biological potency of rat lutropin
1985 • 61 citations
Primary structures of carp gonadotropin subunits deduced from cDNA nucleotide sequences
1988 • 61 citations
Separation of anionic oligosaccharides by high-performance liquid chromatography
1986 • 58 citations
Mutagenesis and Gene Transfer Define Site-Specific Roles of the Gonadotropin Oligosaccharides
1989 • 58 citations
A NEW METHOD OF ASSAY FOR THYROTROPHIC HORMONE
1955 • 57 citations
Nucleotide sequence of a cDNA for the common alpha subunit of the bovine pituitary glycoprotein hormones. Conservation of nucleotides in the 3'-untranslated region of bovine and human pre-alpha subunit mRNAs.
1983 • 56 citations
Studies on the Disulfide Bonds of Glycoprotein Hormones
1974 • 55 citations
The structures of the serine-linked sugar chains on human chorionic gonadotropin
1985 • 55 citations
Structure of carbohydrate units of ovine luteinizing hormone.
1982 • 54 citations
Demonstration of a COOH-terminal extension on equine lutropin by means of a common acid-labile bond in equine lutropin and equine chorionic gonadotropin.
1985 • 54 citations
The Primary Structure of the Porcine Luteinizing-Hormone alpha-Subunit
1973 • 54 citations
AN IMPROVED ASSAY METHOD FOR THYROTROPHIN USING DEPLETION OF I131FROM THE THYROID OF DAY-OLD CHICKS
1957 • 54 citations
Structures, function, and transformational changes of the sugar chains of glycohormones
1988 • 53 citations
Structure of the carbohydrate moieties of alpha subunits of human follitropin, lutropin, and thyrotropin.
1978 • 53 citations
Model studies on N-glycosylation of proteins
1984 • 53 citations
[43] Endoglycosidases from Flavobacterium meningosepticum application to biological problems
1989 • 53 citations
Differential flexibilities in three branches of an N-linked triantennary glycopeptide.
1991 • 51 citations
Assignment of the gene for the beta subunit of thyroid-stimulating hormone to the short arm of human chromosome 1.
1986 • 51 citations
Cloning and DNA sequence analysis of the cDNA for the precursor of the beta chain of bovine follicle stimulating hormone.
1986 • 51 citations
Cell-free sulfation of human and bovine pituitary hormones. Comparison of the sulfated oligosaccharides of lutropin, follitropin, and thyrotropin.
1985 • 51 citations
Molecular cloning and nucleotide sequence analysis of the putative cDNA for the precursor molecule of the chicken LH-β subunit
1989 • 49 citations
The Tryptic Glycopeptides of Bovine Thyrotropin
1969 • 48 citations
Inactivation of follicle-stimulating hormone by enzymic release of sialic acid
1960 • 48 citations
Gonadotropin alpha subunit. Differential processing of free and combined forms in human trophoblast and transfected mouse cells.
1987 • 48 citations
Molecular cloning and sequence analysis of the cDNA for the putative β subunit of the type-II gonadotrophin from the European eel
1990 • 47 citations
Nucleotide Sequence of the Bovine Gene for Follicle-Stimulating Hormone β-Subunit
1988 • 47 citations
Structural requirements for sulfation of asparagine-linked oligosaccharides of lutropin.
1985 • 46 citations
The Asparagine-Linked Sugar Chains of Human Follicle-Stimulating Hormone1
1987 • 45 citations
Structural differences found in the asparagine-linked sugar chains of human chorionic gonadotropins purified from the urine of patients with invasive mole and with choriocarcinoma.
1987 • 45 citations
Carbohydrate Composition of the α-Subunit of Human Choriogonadotropin (hCGα) and the Free α Molecules Produced in Pregnancy: Most Free α and Some Combined hCGα Molecules Are Fucosylated
1990 • 43 citations
Isolation and Characterization of Follicle-Stimulating Hormone and Luteinizing Hormone and Its Subunits from Snapping Turtle (Chelydra serpentina) Pituitaries
1976 • 43 citations
The nucleotide sequences of baboon chorionic gonadotropin β-subunit genes have diverged from the human
1986 • 43 citations
Structure of human luteinizing hormone beta subunit: Evidence for a related carboxyl-terminal sequence among certain peptide hormones
1979 • 42 citations
The role of carbohydrate in human choriogonadotropin (hCG) action. Effects of N-linked carbohydrate chains from hCG and other glycoproteins on hormonal activity
1990 • 41 citations
Variations in the Oligosaccharides on Free and Combined α-Subunits of Human Choriogonadotropin in Pregnancy
1985 • 41 citations
The effects of desialylation on the biologic and immunologic activity of human pituitary luteinizing hormone
1971 • 41 citations
Cloning and DNA sequence analysis of the cDNA for the precursor of porcine follicle stimulating hormone (FSH) β subunit
1988 • 41 citations
The gene for the β subunit of porcine FSH: absence of consensus oestrogen-responsive element and presence of retroposons
1990 • 40 citations
The alpha subunit of pituitary glycoprotein hormones. Formation of three-dimensional structure during cell-free biosynthesis.
1983 • 40 citations
Human pituitary lutropin
1975 • 40 citations
Nucleotide (cDNA) sequence encoding the horse gonadotrophin α-subunit
1987 • 40 citations
The complete amino acid sequences of α subunits of chum salmon gonadotropins
1990 • 39 citations
Organization and Nucleotide Sequence of the Gene Encoding the β-Subunit of Murine Thyrotropin
1988 • 38 citations
Human pituitary thyrotropin. The primary structure of the α and β subunits
1977 • 38 citations
Role of disulfide bond formation in the folding of human chorionic gonadotropin beta subunit into an alpha beta dimer assembly-competent form.
1990 • 38 citations
Conversion of lysine 91 to methionine or glutamic acid in human choriogonadotropin alpha results in the loss of cAMP inducibility.
1991 • 37 citations
A NEW IN VITRO ASSAY FOR THYROIDSTIMULATING HORMONE
1967 • 36 citations
Cloning and sequence analysis of the cDNA for the precursor of the beta subunit of ovine luteinizing hormone
1990 • 36 citations
Amphibian lutropin and follitropin from the bullfrog Rana catesbeiana
1992 • 36 citations
The Primary Structure of Bovine Thyrotropin
1971 • 36 citations
Preliminary X-ray Diffraction Analysis of Human Chorionic Gonadotropin
1989 • 35 citations
Studies of the Specific Role of the Subunits of Choriogonadotropin for Biological, Immunological and Physical Properties of the Hormone. Digestion of the alpha-Subunit with Carboxypeptidase A
1979 • 35 citations
Expression of the gene for the beta subunit of mouse thyrotropin results in multiple mRNAs differing in their 5′-untranslated regions.
1987 • 35 citations
Cloning and sequence analysis of the cDNA for the pituitary glycoprotein hormone α-subunit of the European eel
1990 • 35 citations
Konformationsanalyse der verzweigten pentasaccharid-sequenz der “bisected” struktur von N-glycoproteinen
1986 • 34 citations
A reevaluation of the amino acid sequence of human follitropin β-subunit
1988 • 34 citations
A comparison of preparations of highly purified human pituitary luteinizing hormone: differences in the luteinizing hormone potencies as determined by in vivo bioassays, in vitro bioassay and immunoassay
1982 • 34 citations
Characterization of a cleavage product in the human choriogonadotropin β-subunit
1988 • 34 citations
Primary and secondary structural determinants in the receptor binding sequence .beta.-(38-57) from human luteinizing hormone
1988 • 34 citations
Human pituitary thyrotropin: Primary structure of the hormone specific β subunit
1973 • 34 citations
Primary structure of the ovine pituitary follitropin α-subunit
1981 • 34 citations
N-Linked Oligosaccharides Are not Required for Hormone Binding of the Lutropin Receptor in a Leydig Tumor Cell Line and Rat Granulosa Cells
1990 • 34 citations
Amino acid sequence of the beta-subunit of the follicle-stimulating hormone from equine pituitary glands
1978 • 33 citations
Characterization of cleavage products in selected human lutropin preparations
1986 • 33 citations
Studies of disulfide bond location in ovine lutropin β subunit
1977 • 33 citations
Cloning and DNA sequence analysis of the cDNA for the precursor of ovine follicle stimulating hormone β-subunit
1989 • 32 citations
Studies on the chemistry and bioassay of thyrotropins from bovine pituitaries, transplantable pituitary tumors of mice, and blood plasma.
1960 • 32 citations
Kinetic roles and conformational properties of the non-native two-disulphide intermediates in the refolding of bovine pancreatic trypsin inhibitor
1992 • 32 citations
Purification, characterization, and molecular cloning of gonadotropin subunits of silver carp (Hypophthalmichthys molitrix)
1990 • 31 citations
Evidence for a single rat thyrotropin-β-subunit gene: Thyroidectomy increases its mRNA
1985 • 30 citations
Structure determination of the major N‐ and O‐linked carbohydrate chains of the β subunit from equine chorionic gondotropin
1990 • 30 citations
Partial reduction of disulfide bonds in the hormone-specific subunits of TSH and LH
1975 • 30 citations
Studies of the heterogeneity of human pituitary LH by fast protein liquid chromatography
1985 • 30 citations
The gene for the β subunit of porcine LH: clusters of GC boxes and CACCC elements
1990 • 30 citations
Bioassays of Follicle Stimulating Hormone
1988 • 29 citations
A New Role for Follicle-Stimulating Hormone in the Regulation of Calcium Flux in Sertoli Cells: Inhibition of Na+/Ca++ Exchange*
1991 • 29 citations
Purification of human pituitary LH and thyrotrophin by hydrophobic chromatography
1990 • 29 citations
Molecular cloning of cDNAs for precursors of porcine pituitary glycoprotein hormone common α-subunit and of thyroid stimulating hormone β-subunit
1989 • 28 citations
The common α subunit of bovine glycoprotein hormones: Limited formation of native structure by the totally nonglycosylated polypeptide chain
1985 • 28 citations
Chromosomal assignment of human genes for gastrin, thyrotropin (TSH)-β subunit and C-erbB-2 by chromosome sorting combined with velocity sedimentation and southern hybridization
1986 • 28 citations
Development and Characterization of a New, Highly Specific Antibody to the Human Chorionic Gonadotropin-β Fragment*
1991 • 28 citations
Site‐specific N‐glycosylation of ovine lutropin
1990 • 28 citations
Primary structure of two mRNAs encoding putative salmon α-subunits of pituitary glycoprotein hormone
1988 • 27 citations
The Role of Subunit Sialic Acid in the Thyrotropic and Gonadotropic Activities of Human Chorionic Gonadotropin*
1987 • 27 citations
Highly Specific and Sensitive Hybridoma Antibodies against the α-Subunit of Human Glycoprotein Hormones*
1985 • 27 citations
Studies on the disulfide bonds of glycoprotein hormones. Formation and properties of 11,35-bis(S-alkyl) derivatives of the alpha subunit.
1979 • 27 citations
Cloning and DNA sequence analysis of the cDNA for the common α-subunit of the ovine pitultary glycoprotein hormones
1989 • 26 citations
Porcine Thyrotropin. The Amino-Acid Sequence of the alpha and beta Subunits
1976 • 25 citations
Amphibian lutropin from the bullfrog Rana catesbeiana
1992 • 25 citations
Sialic Acids, but Not Their Linkage to Galactose Residues, Are Required for Full Expression of the Biological Activity of Human Chorionic Gonadotropin1
1989 • 25 citations
Pike eel (Muraenesox cinereus) gonadotropin
1989 • 24 citations
The structures of the carbohydrate moieties of the α subunit of human chorionic gonadotrophin
1976 • 24 citations
Nucleotide sequence of the cDNA encoding the common α subunit of the chicken pituitary glycoprotein hormones
1992 • 23 citations
A NEW BIOASSAY TECHNIQUE FOR THE MEASUREMENT IN VITRO OF THYROTROPHIC HORMONE IN SERUM AND IN PITUITARY EXTRACTS
1962 • 23 citations
THE PRIMARY STRUCTURE OF OVINE INTERSTITIAL CELL STIMULATING HORMONE IV: DISULFIDE BRIDGES OF THE β SUBUNIT
1975 • 22 citations
Altered glycosylation of human chorionic gonadotropin decreases its hormonal activity as determined by cyclic-adenosine 3',5'-monophosphate production in MA-10 cells
1990 • 22 citations
Circular Dichroism of Pituitary Hormones
1979 • 22 citations
Separation of human glycoprotein hormones and their subunits by reversed-phase liquid chromatography
1990 • 22 citations
Differences in the carbohydrate portion of the α subunit of porcine lutropin (LH), follitropin (FSH) and thyrotropin (TSH)
1975 • 21 citations
Polymorphism of human pituitary lutropin (LH)
1984 • 20 citations
Differential carbohydrate processing and secretion of thyrotropin and free alpha subunit. Effects of 1-deoxynojirimycin.
1988 • 20 citations
Difference in Sizes of Human Compared to Murine α-Subunits of the Glycoprotein Hormones Arises by a Four-Codon Gene Deletion or Insertion*
1983 • 19 citations
Structural differences found in the sugar chains of eutopic and ectopic free α-subunits of human glycoprotein hormone
1988 • 19 citations
Molecular Cloning of the Rhesus Glycoprotein Hormone α-Subunit Gene
1991 • 19 citations
Studies on human chorionic gonadotrophin. II. Chemical composition and its relation to biological activity.
1968 • 16 citations
Altered Glycosylation Is Induced in Both α- and β-Subunits of Human Chorionic Gonadotropin Produced by Choriocarcinoma1
1988 • 16 citations
The Antigenic Structure of the Human Glycoprotein Hormone α-Subunit. I. Characterization of Anti-α Monoclonal Antibodies*
1990 • 16 citations
OBSERVATIONS ON THE ASSAY OF HUMAN URINARY FOLLICLE-STIMULATING HORMONE BY THE AUGMENTATION TEST IN MICE
1966 • 15 citations
Epitope mapping of the receptor-bound agonistic form of human chorionic gonadotropin (hCG) in comparison to the antagonistic form (deglycosylated hCG)
1991 • 15 citations
Synthetic human follicle-stimulating hormone-beta-(1-15) peptide-amide binds Ca2+ and possesses sequence similarity to calcium binding sites of calmodulin.
1992 • 14 citations
DISULFIDE BONDS OF GLYCOPROTEIN HORMONES: Their Selective Reduction in the β Subunits of Bovine Lutropin and Thyrotropin
1981 • 13 citations
Cloning and DNA sequence analysis of the cDNA for the precursor of porcine luteinizing hormone (LH) β subunit
1989 • 12 citations
Studies of human pituitary LH containing internally cleaved β subunit
1991 • 12 citations
Structure of a receptor-binding fragment from human luteinizing hormone beta-subunit determined by [1H]- and [15N]nuclear magnetic resonance spectroscopy.
1992 • 11 citations
Nucleic acid and amino acid sequences of dog βLH: comparison to rat, cow and human βLH
1987 • 11 citations
An antipodean perception of the mode of action of glycoprotein hormones
1992 • 9 citations
PURIFICATION AND PROPERTIES OF THE SUBUNITS OF HUMAN PITUITARY FOLLICLE-STIMULATING HORMONE
1976 • 8 citations
THYROID-STIMULATING AND LIPOLYTIC ACTIVITIES OF PURIFIED PREPARATIONS OF HUMAN THYROID-STIMULATING HORMONE
1972 • 8 citations
Heterogeneity of free alpha-subunit in term placenta.
1983 • 8 citations
Primary structure of sperm whale luteinizing hormone
1986 • 8 citations
Human luteinizing hormone. Structure and function of some preparations.
1977 • 8 citations
Reevaluation of the amino acid sequence of porcine follitropin
1989 • 6 citations
SIALIC ACID AND TRYPTOPHAN CONTENT OF SUBUNITS OF HUMAN PITUITARY LUTEINIZING HORMONE
1973 • 5 citations
Incompletely processed LH molecules synthesized by rat gonadotrophs treated with inhibitors of oligosaccharide processing
1989 • 4 citations