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Molecular structures of glycoprotein hormones and functions of their carbohydrate components

Data up to Jan 2025

Published1992
Citations161
References231

Total Citations Per Year

Abstract

References (231)

Two distinct classes of carbohydrate-recognition domains in animal lectins.

1988 • 1,259 citations

Lutropin-Choriogonadotropin Receptor: An Unusual Member of the G Protein-Coupled Receptor Family

1989 • 955 citations

ASSAY OF THE FOLLICLE STIMULATING HORMONE BASED ON THE AUGMENTATION WITH HUMAN CHORIONIC GONADOTROPIN

1953 • 696 citations

The Role of Polyprenol-Linked Sugars in Glycoprotein Synthesis

1976 • 680 citations

TOPOGRAPHY OF GLYCOSYLATION IN THE ROUGH ENDOPLASMIC RETICULUM AND GOLGI APPARATUS

1987 • 596 citations

Characterization of Several Clonal Lines of Cultured Ley dig Tumor Cells: Gonadotropin Receptors and Steroidogenic Responses*

1981 • 596 citations

[17] Hydrazinolysis of asparagine-linked sugar chains to produce free oligosaccharides

1982 • 446 citations

Lectins: Their Multiple Endogenous Cellular Functions

1981 • 431 citations

THE BIOASSAY OF THYROTROPIN IN SERUM1

1958 • 429 citations

Glycoproteins

1970 • 408 citations

AN IMPROVED IN VITRO BIOASSAY METHOD FOR MEASURING LUTEINIZING HORMONE (LH) ACTIVITY USING MOUSE LEYDIG CELL PREPARATIONS

1974 • 385 citations

[6] Analysis of oligosaccharides by gel filtration

1982 • 350 citations

Asparagine-linked oligosaccharides on lutropin, follitropin, and thyrotropin. I. Structural elucidation of the sulfated and sialylated oligosaccharides on bovine, ovine, and human pituitary glycoprotein hormones.

1988 • 344 citations

F.A.B.-Mass Spectrometry of Carbohydrates

1987 • 340 citations

Evolution of the genes for the β subunits of human chorionic gonadotropin and luteinizing hormone

1984 • 336 citations

The synthesis of complex-type oligosaccharides. II. Characterization of the processing intermediates in the synthesis of the complex oligosaccharide units of the vesicular stomatitis virus G protein

1978 • 335 citations

Pituitary glycoprotein hormone oligosaccharides: Structure, synthesis and function of the asparagine-linked oligosaccharides on lutropin, follitropin and thyrotropin

1988 • 302 citations

Isolation, cloning and sequence analysis of the cDNA for the α-subunit of human chorionic gonadotropin

1979 • 298 citations

The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta subunit.

1975 • 292 citations

The cDNA for the β-subunit of human chorionic gonadotropin suggests evolution of a gene by readthrough into the 3′-untranslated region

1980 • 271 citations

A HIGHLY SENSITIVE IN VITRO BIOASSAY FOR LUTEINIZING HORMONE AND CHORIONIC GONADOTROPIN: TESTOSTERONE PRODUCTION BY DISPERSED LEYDIG CELLS.

1974 • 265 citations

Role of carbohydrate of human chorionic gonadotropin in the mechanism of hormone action

1975 • 251 citations

Structures of N-glycosidic carbohydrate units of human chorionic gonadotropin.

1979 • 242 citations

Human Chorionic Gonadotropin

1973 • 226 citations

Site specificity of the chorionic gonadotropin N-linked oligosaccharides in signal transduction

1989 • 225 citations

A Role for Glycosylation of the α Subunit in Transduction of Biological Signal in Glycoprotein Hormones

1985 • 222 citations

Evolution of Gonadotropin Structure and Function

1977 • 216 citations

[18] Lectin affinity chromatography of glycopeptides

1987 • 215 citations

Structure and location of the O-glycosidic carbohydrate units of human chorionic gonadotropin.

1979 • 215 citations

The glycoprotein hormones: recent studies of structure‐function relationships

1988 • 214 citations

The role of the asparagine-linked oligosaccharides of the alpha subunit in the secretion and assembly of human chorionic gonadotrophin.

1988 • 203 citations

Conformational restrictions on the pathway of folding and unfolding of the pancreatic trypsin inhibitor

1977 • 188 citations

The Biological Role of the Carboxyl-Terminal Extension of Human Chorionic Gonadotroin β-Subunit

1990 • 187 citations

InVitroBioassay of LH in Human Serum: The Rat Interstitial Cell Testosterone (RICT) Assay

1976 • 177 citations

Thyroid-Stimulating Hormone: Biosynthesis, Cell Biology, and Bioactivity

1990 • 175 citations

alpha Subunit of rat pituitary glycoprotein hormones. Primary structure of the precursor determined from the nucleotide sequence of cloned cDNAs.

1982 • 160 citations

Structure–Function Relationships of Gonadotropins

1987 • 158 citations

Structures of the asparagine-linked sugar chains of human chorionic gonadotropin produced in choriocarcinoma. Appearance of triantennary sugar chains and unique biantennary sugar chains.

1983 • 154 citations

Immunological and Biological Activity of HCG Following Progressive Desialylation

1971 • 150 citations

Structural elucidation of the disulfated oligosaccharide from bovine lutropin.

1985 • 148 citations

The Primary Structure of Bovine Thyrotropin

1971 • 141 citations

The Binding of Desialylated Glycoproteins by Plasma Membranes of Rat Liver

1972 • 138 citations

Studies on the Structure of Thyrotropin: Its Relationship to Luteinizing Hormone

1971 • 138 citations

DNA Sequence and Regional Assignment of the Human Follicle-Stimulating Hormone β-Subunit Gene to the Short Arm of Human Chromosome 11

1987 • 131 citations

Chromosome assignment of genes encoding the? and? subunits of glycoprotein hormones in man and mouse

1983 • 128 citations

Use of monoclonal antibodies to subunits of human chorionic gonadotropin to examine the orientation of the hormone in its complex with receptor.

1982 • 125 citations

Oligosaccharide moieties of glycoprotein hormones: bovine lutropin resists enzymatic deglycosylation because of terminal O-sulfated N-acetylhexosamines.

1980 • 122 citations

Conformational transitions in N-linked oligosaccharides

1986 • 120 citations

Solution conformation of .alpha.-D-(1-3)- and .alpha.-D-(1-6)-linked oligomannosides using proton nuclear magnetic resonance

1983 • 120 citations

A map of the hCG beta-LH beta gene cluster.

1986 • 118 citations

The β-subunit of follicle-stimulating hormone is deleted in patients with aniridia and Wilms' tumour, allowing a further definition of the WAGR locus

1986 • 118 citations

The Heterogeneity of Human Chorionic Gonadotropin (hCG). III. The Occurrence and Biological and Immunological Activities of Nicked hCG*

1991 • 118 citations

Human Follicle-Stimulating Hormone β-Subunit Gene Encodes Multiple Messenger Ribonucleic Acids

1988 • 116 citations

Structures of the Asparagine-Linked Sugar Chains of Human Chorionic Gonadotropin

1980 • 115 citations

Rapid separation of anionic oligosaccharide species by high performance liquid chromatography

1981 • 111 citations

The Primary Structure of Ovine Luteinizing Hormone

1972 • 110 citations

Granulosa Cell Aromatase Bioassay for Follicle-Stimulating Hormone: Validation and Application of the Method*

1986 • 108 citations

Isolation and characterization of the human thyrotropin beta-subunit gene. Differences in gene structure and promoter function from murine species.

1988 • 106 citations

A new force‐field program for the calculation of glycopeptides and its application to a heptacosapeptide‐decasaccharide of immunoglobulin G1

1990 • 106 citations

THE PRIMARY STRUCTURE OF THE HORMONE-SPECIFIC, BETA SUBUNIT OF HUMAN PITUITARY LUTEINIZING HORMONE (hLH)

1973 • 102 citations

Purification of an alternate form of the alpha subunit of the glycoprotein hormones from bovine pituitaries and identification of its O-linked oligosaccharide.

1983 • 100 citations

Human chorionic gonadotropin: A proposal for the amino acid sequence

1973 • 99 citations

Isolation and structure determination of the intact sialylated N‐linked carbohydrate chains of recombinant human follitropin expressed in Chinese hamster ovary cells

1990 • 98 citations

The sialylated oligosaccharides of recombinant bovine lutropin modulate hormone bioactivity.

1990 • 97 citations

Effects of Progressive Desialylation on the Rate of Disappearance of Immunoreactive HCG from Plasma in Rats

1971 • 96 citations

Nucleotide sequence of the mRNA encoding the pre-alpha-subunit of mouse thyrotropin.

1981 • 96 citations

The Primary Structure of Ovine Luteinizing Hormone

1972 • 95 citations

Nucleotide sequence of the cDNA encoding the precursor of the beta subunit of rat lutropin.

1983 • 95 citations

Molecular cloning of the human thyrotropin‐β subunit gene

1985 • 93 citations

Free alpha molecules from pregnancy stimulate secretion of prolactin from human decidual cells: a novel function for free alpha in pregnancy.

1991 • 92 citations

Amino acid sequence of the beta subunit of follicle-stimulating hormone from human pituitary glands.

1976 • 91 citations

NMR investigations of the N‐linked oligosaccharides at individual glycosylation sites of human lutropin

1991 • 91 citations

A SENSITIVE AND SPECIFIC IN VITRO BIOASSAY METHOD FOR THE MEASUREMENT OF FOLLICLE-STIMULATING HORMONE ACTIVITY

1979 • 90 citations

Glycosylation of Thyroid-Stimulating Hormone in Pituitary Tumor Cells: Influence of High Mannose Oligosaccharide Units on Subunit Aggregation, Combination, and Intracellular Degradation

1983 • 89 citations

Different asparagine-linked sugar chains on the two polypeptide chains of human chorionic gonadotropin

1980 • 87 citations

Comparisons between the α Chain of Bovine Thyrotropin and the CI Chain of Luteinizing Hormone

1971 • 85 citations

The gene for the beta subunit of bovine luteinizing hormone encodes a gonadotropin mRNA with an unusually short 5'-untranslated region.

1985 • 84 citations

The Antigenic Surface of Human Chorionic Gonadotropin as Mapped by Murine Monclonal Antibodies*

1986 • 83 citations

Comparative study of the mucin-type sugar chains of human chorionic gonadotropin present in the urine of patients with trophoblastic diseases and healthy pregnant women.

1988 • 82 citations

Structural studies on equine glycoprotein hormones. Amino acid sequence of equine chorionic gonadotropin beta-subunit.

1987 • 80 citations

A synthetic peptide corresponding to human FSH beta-subunit 33-53 binds to FSH receptor, stimulates basal estradiol biosynthesis, and is a partial antagonist of FSH

1990 • 79 citations

Size fractionation of anionic oligosaccharides and glycopeptides by high-performance liquid chromatography

1983 • 79 citations

Identification of a follicle-stimulating hormone receptor-binding region in hFSH-beta-(81-95) using synthetic peptides.

1990 • 77 citations

Molecular cloning and sequencing of salmon gonadotropin β subunit

1986 • 77 citations

HUMAN FOLLICLE STIMULATING HORMONE: FIRST PROPOSAL FOR THE AMINO ACID SEQUENCE OF THE HORMONE-SPECIFIC, β SUBUNIT (hFSHβ)

1974 • 77 citations

Combination of rat lutropin subunits occurs early in the secretory pathway.

1982 • 76 citations

Site-specific N-glycosylation of human chorionic gonadotrophin—structural analysis of glycopeptides by one- and two-dimensional1H NMR spectroscopy

1991 • 76 citations

Inhibition of adenylyl cyclase activity in rat corpora luteal tissue by glycopeptides of human chorionic gonadotropin and the .alpha.-subunit of human chorionic gonadotropin

1985 • 75 citations

Cloning of cDNA encoding the pre-beta subunit of mouse thyrotropin.

1983 • 74 citations

Tertiary structure in N-linked oligosaccharides

1987 • 74 citations

Molecular Cloning and Nucleotide Sequence Analysis of Complementary Deoxyribonucleic Acid for the β-Subunit of Rat Follicle Stimulating Hormone

1987 • 73 citations

Antigenic Features of Human Follicle Stimulating Hormone Delineated by Monoclonal Antibodies and Construction of an Immunoradiomometric Assay

1988 • 73 citations

Thyroid-stimulating hormone subunit processing and combination in microsomal subfractions of mouse pituitary tumor.

1982 • 72 citations

Fundulus heteroclitus gonadotropins. 3. Cloning and sequencing of gonadotropic hormone (GTH) I and II β-subunits using the polymerase chain reaction

1992 • 71 citations

Assignment of disulfide bonds in the beta subunit of human chorionic gonadotropin.

1981 • 71 citations

The complete amino acid sequences of β-subunits of two distinc chum salmon GTHs

1988 • 70 citations

Differential processing of Asn-linked oligosaccharides on pituitary glycoprotein hormones: implications for biologic function

1986 • 70 citations

Thyroid Hormone Decreases Thyrotropin Subunit mRNA Levels in Rat Anterior Pituitary

1984 • 68 citations

Biologically active covalently cross-linked glycoprotein hormones and the effects of modification of the COOH-terminal region of their alpha subunits.

1979 • 67 citations

Structural studies on equine glycoprotein hormones. Amino acid sequence of equine lutropin beta-subunit.

1987 • 65 citations

Assignment of disulfide bonds in the alpha subunit of human chorionic gonadotropin.

1980 • 64 citations

Isolation and Characterization of the Gene Encoding the β-Subunit of Rat Follicle-Stimulating Hormone

1989 • 64 citations

Crystallization and characterization of human chorionic gonadotropin in chemically deglycosylated and enzymically desialylated states

1989 • 63 citations

Structure of the Lutropin/Choriogonadotropin Receptor

1990 • 63 citations

The sequence of a cloned cDNA for the beta subunit of bovine thyrotropin predicts a protein containing both NH2-and COOH-terminal extensions.

1984 • 63 citations

Luteinizing Hormone

1973 • 62 citations

The primary structure of ovine interstitial cell-stimulating hormone

1972 • 61 citations

Sialic acid moiety is responsible for the charge heterogeneity and the biological potency of rat lutropin

1985 • 61 citations

Primary structures of carp gonadotropin subunits deduced from cDNA nucleotide sequences

1988 • 61 citations

Separation of anionic oligosaccharides by high-performance liquid chromatography

1986 • 58 citations

Mutagenesis and Gene Transfer Define Site-Specific Roles of the Gonadotropin Oligosaccharides

1989 • 58 citations

A NEW METHOD OF ASSAY FOR THYROTROPHIC HORMONE

1955 • 57 citations

Nucleotide sequence of a cDNA for the common alpha subunit of the bovine pituitary glycoprotein hormones. Conservation of nucleotides in the 3'-untranslated region of bovine and human pre-alpha subunit mRNAs.

1983 • 56 citations

Studies on the Disulfide Bonds of Glycoprotein Hormones

1974 • 55 citations

The structures of the serine-linked sugar chains on human chorionic gonadotropin

1985 • 55 citations

Structure of carbohydrate units of ovine luteinizing hormone.

1982 • 54 citations

Demonstration of a COOH-terminal extension on equine lutropin by means of a common acid-labile bond in equine lutropin and equine chorionic gonadotropin.

1985 • 54 citations

The Primary Structure of the Porcine Luteinizing-Hormone alpha-Subunit

1973 • 54 citations

AN IMPROVED ASSAY METHOD FOR THYROTROPHIN USING DEPLETION OF I131FROM THE THYROID OF DAY-OLD CHICKS

1957 • 54 citations

Structures, function, and transformational changes of the sugar chains of glycohormones

1988 • 53 citations

Structure of the carbohydrate moieties of alpha subunits of human follitropin, lutropin, and thyrotropin.

1978 • 53 citations

Model studies on N-glycosylation of proteins

1984 • 53 citations

[43] Endoglycosidases from Flavobacterium meningosepticum application to biological problems

1989 • 53 citations

Differential flexibilities in three branches of an N-linked triantennary glycopeptide.

1991 • 51 citations

Assignment of the gene for the beta subunit of thyroid-stimulating hormone to the short arm of human chromosome 1.

1986 • 51 citations

Cloning and DNA sequence analysis of the cDNA for the precursor of the beta chain of bovine follicle stimulating hormone.

1986 • 51 citations

Cell-free sulfation of human and bovine pituitary hormones. Comparison of the sulfated oligosaccharides of lutropin, follitropin, and thyrotropin.

1985 • 51 citations

Molecular cloning and nucleotide sequence analysis of the putative cDNA for the precursor molecule of the chicken LH-β subunit

1989 • 49 citations

The Tryptic Glycopeptides of Bovine Thyrotropin

1969 • 48 citations

Inactivation of follicle-stimulating hormone by enzymic release of sialic acid

1960 • 48 citations

Gonadotropin alpha subunit. Differential processing of free and combined forms in human trophoblast and transfected mouse cells.

1987 • 48 citations

Molecular cloning and sequence analysis of the cDNA for the putative β subunit of the type-II gonadotrophin from the European eel

1990 • 47 citations

Nucleotide Sequence of the Bovine Gene for Follicle-Stimulating Hormone β-Subunit

1988 • 47 citations

Structural requirements for sulfation of asparagine-linked oligosaccharides of lutropin.

1985 • 46 citations

The Asparagine-Linked Sugar Chains of Human Follicle-Stimulating Hormone1

1987 • 45 citations

Structural differences found in the asparagine-linked sugar chains of human chorionic gonadotropins purified from the urine of patients with invasive mole and with choriocarcinoma.

1987 • 45 citations

Carbohydrate Composition of the α-Subunit of Human Choriogonadotropin (hCGα) and the Free α Molecules Produced in Pregnancy: Most Free α and Some Combined hCGα Molecules Are Fucosylated

1990 • 43 citations

Isolation and Characterization of Follicle-Stimulating Hormone and Luteinizing Hormone and Its Subunits from Snapping Turtle (Chelydra serpentina) Pituitaries

1976 • 43 citations

The nucleotide sequences of baboon chorionic gonadotropin β-subunit genes have diverged from the human

1986 • 43 citations

Structure of human luteinizing hormone beta subunit: Evidence for a related carboxyl-terminal sequence among certain peptide hormones

1979 • 42 citations

The role of carbohydrate in human choriogonadotropin (hCG) action. Effects of N-linked carbohydrate chains from hCG and other glycoproteins on hormonal activity

1990 • 41 citations

Variations in the Oligosaccharides on Free and Combined α-Subunits of Human Choriogonadotropin in Pregnancy

1985 • 41 citations

The effects of desialylation on the biologic and immunologic activity of human pituitary luteinizing hormone

1971 • 41 citations

Cloning and DNA sequence analysis of the cDNA for the precursor of porcine follicle stimulating hormone (FSH) β subunit

1988 • 41 citations

The gene for the β subunit of porcine FSH: absence of consensus oestrogen-responsive element and presence of retroposons

1990 • 40 citations

The alpha subunit of pituitary glycoprotein hormones. Formation of three-dimensional structure during cell-free biosynthesis.

1983 • 40 citations

Human pituitary lutropin

1975 • 40 citations

Nucleotide (cDNA) sequence encoding the horse gonadotrophin α-subunit

1987 • 40 citations

The complete amino acid sequences of α subunits of chum salmon gonadotropins

1990 • 39 citations

Organization and Nucleotide Sequence of the Gene Encoding the β-Subunit of Murine Thyrotropin

1988 • 38 citations

Human pituitary thyrotropin. The primary structure of the α and β subunits

1977 • 38 citations

Role of disulfide bond formation in the folding of human chorionic gonadotropin beta subunit into an alpha beta dimer assembly-competent form.

1990 • 38 citations

Conversion of lysine 91 to methionine or glutamic acid in human choriogonadotropin alpha results in the loss of cAMP inducibility.

1991 • 37 citations

A NEW IN VITRO ASSAY FOR THYROIDSTIMULATING HORMONE

1967 • 36 citations

Cloning and sequence analysis of the cDNA for the precursor of the beta subunit of ovine luteinizing hormone

1990 • 36 citations

Amphibian lutropin and follitropin from the bullfrog Rana catesbeiana

1992 • 36 citations

The Primary Structure of Bovine Thyrotropin

1971 • 36 citations

Preliminary X-ray Diffraction Analysis of Human Chorionic Gonadotropin

1989 • 35 citations

Studies of the Specific Role of the Subunits of Choriogonadotropin for Biological, Immunological and Physical Properties of the Hormone. Digestion of the alpha-Subunit with Carboxypeptidase A

1979 • 35 citations

Expression of the gene for the beta subunit of mouse thyrotropin results in multiple mRNAs differing in their 5′-untranslated regions.

1987 • 35 citations

Cloning and sequence analysis of the cDNA for the pituitary glycoprotein hormone α-subunit of the European eel

1990 • 35 citations

Konformationsanalyse der verzweigten pentasaccharid-sequenz der “bisected” struktur von N-glycoproteinen

1986 • 34 citations

A reevaluation of the amino acid sequence of human follitropin β-subunit

1988 • 34 citations

A comparison of preparations of highly purified human pituitary luteinizing hormone: differences in the luteinizing hormone potencies as determined by in vivo bioassays, in vitro bioassay and immunoassay

1982 • 34 citations

Characterization of a cleavage product in the human choriogonadotropin β-subunit

1988 • 34 citations

Primary and secondary structural determinants in the receptor binding sequence .beta.-(38-57) from human luteinizing hormone

1988 • 34 citations

Human pituitary thyrotropin: Primary structure of the hormone specific β subunit

1973 • 34 citations

Primary structure of the ovine pituitary follitropin α-subunit

1981 • 34 citations

N-Linked Oligosaccharides Are not Required for Hormone Binding of the Lutropin Receptor in a Leydig Tumor Cell Line and Rat Granulosa Cells

1990 • 34 citations

Amino acid sequence of the beta-subunit of the follicle-stimulating hormone from equine pituitary glands

1978 • 33 citations

Characterization of cleavage products in selected human lutropin preparations

1986 • 33 citations

Studies of disulfide bond location in ovine lutropin β subunit

1977 • 33 citations

Cloning and DNA sequence analysis of the cDNA for the precursor of ovine follicle stimulating hormone β-subunit

1989 • 32 citations

Studies on the chemistry and bioassay of thyrotropins from bovine pituitaries, transplantable pituitary tumors of mice, and blood plasma.

1960 • 32 citations

Kinetic roles and conformational properties of the non-native two-disulphide intermediates in the refolding of bovine pancreatic trypsin inhibitor

1992 • 32 citations

Purification, characterization, and molecular cloning of gonadotropin subunits of silver carp (Hypophthalmichthys molitrix)

1990 • 31 citations

Evidence for a single rat thyrotropin-β-subunit gene: Thyroidectomy increases its mRNA

1985 • 30 citations

Structure determination of the major N‐ and O‐linked carbohydrate chains of the β subunit from equine chorionic gondotropin

1990 • 30 citations

Partial reduction of disulfide bonds in the hormone-specific subunits of TSH and LH

1975 • 30 citations

Studies of the heterogeneity of human pituitary LH by fast protein liquid chromatography

1985 • 30 citations

The gene for the β subunit of porcine LH: clusters of GC boxes and CACCC elements

1990 • 30 citations

Bioassays of Follicle Stimulating Hormone

1988 • 29 citations

A New Role for Follicle-Stimulating Hormone in the Regulation of Calcium Flux in Sertoli Cells: Inhibition of Na+/Ca++ Exchange*

1991 • 29 citations

Purification of human pituitary LH and thyrotrophin by hydrophobic chromatography

1990 • 29 citations

Molecular cloning of cDNAs for precursors of porcine pituitary glycoprotein hormone common α-subunit and of thyroid stimulating hormone β-subunit

1989 • 28 citations

The common α subunit of bovine glycoprotein hormones: Limited formation of native structure by the totally nonglycosylated polypeptide chain

1985 • 28 citations

Chromosomal assignment of human genes for gastrin, thyrotropin (TSH)-β subunit and C-erbB-2 by chromosome sorting combined with velocity sedimentation and southern hybridization

1986 • 28 citations

Development and Characterization of a New, Highly Specific Antibody to the Human Chorionic Gonadotropin-β Fragment*

1991 • 28 citations

Site‐specific N‐glycosylation of ovine lutropin

1990 • 28 citations

Primary structure of two mRNAs encoding putative salmon α-subunits of pituitary glycoprotein hormone

1988 • 27 citations

The Role of Subunit Sialic Acid in the Thyrotropic and Gonadotropic Activities of Human Chorionic Gonadotropin*

1987 • 27 citations

Highly Specific and Sensitive Hybridoma Antibodies against the α-Subunit of Human Glycoprotein Hormones*

1985 • 27 citations

Studies on the disulfide bonds of glycoprotein hormones. Formation and properties of 11,35-bis(S-alkyl) derivatives of the alpha subunit.

1979 • 27 citations

Cloning and DNA sequence analysis of the cDNA for the common α-subunit of the ovine pitultary glycoprotein hormones

1989 • 26 citations

Porcine Thyrotropin. The Amino-Acid Sequence of the alpha and beta Subunits

1976 • 25 citations

Amphibian lutropin from the bullfrog Rana catesbeiana

1992 • 25 citations

Sialic Acids, but Not Their Linkage to Galactose Residues, Are Required for Full Expression of the Biological Activity of Human Chorionic Gonadotropin1

1989 • 25 citations

Pike eel (Muraenesox cinereus) gonadotropin

1989 • 24 citations

The structures of the carbohydrate moieties of the α subunit of human chorionic gonadotrophin

1976 • 24 citations

Nucleotide sequence of the cDNA encoding the common α subunit of the chicken pituitary glycoprotein hormones

1992 • 23 citations

A NEW BIOASSAY TECHNIQUE FOR THE MEASUREMENT IN VITRO OF THYROTROPHIC HORMONE IN SERUM AND IN PITUITARY EXTRACTS

1962 • 23 citations

THE PRIMARY STRUCTURE OF OVINE INTERSTITIAL CELL STIMULATING HORMONE IV: DISULFIDE BRIDGES OF THE β SUBUNIT

1975 • 22 citations

Altered glycosylation of human chorionic gonadotropin decreases its hormonal activity as determined by cyclic-adenosine 3',5'-monophosphate production in MA-10 cells

1990 • 22 citations

Circular Dichroism of Pituitary Hormones

1979 • 22 citations

Separation of human glycoprotein hormones and their subunits by reversed-phase liquid chromatography

1990 • 22 citations

Differences in the carbohydrate portion of the α subunit of porcine lutropin (LH), follitropin (FSH) and thyrotropin (TSH)

1975 • 21 citations

Polymorphism of human pituitary lutropin (LH)

1984 • 20 citations

Differential carbohydrate processing and secretion of thyrotropin and free alpha subunit. Effects of 1-deoxynojirimycin.

1988 • 20 citations

Difference in Sizes of Human Compared to Murine α-Subunits of the Glycoprotein Hormones Arises by a Four-Codon Gene Deletion or Insertion*

1983 • 19 citations

Structural differences found in the sugar chains of eutopic and ectopic free α-subunits of human glycoprotein hormone

1988 • 19 citations

Molecular Cloning of the Rhesus Glycoprotein Hormone α-Subunit Gene

1991 • 19 citations

Studies on human chorionic gonadotrophin. II. Chemical composition and its relation to biological activity.

1968 • 16 citations

Altered Glycosylation Is Induced in Both α- and β-Subunits of Human Chorionic Gonadotropin Produced by Choriocarcinoma1

1988 • 16 citations

The Antigenic Structure of the Human Glycoprotein Hormone α-Subunit. I. Characterization of Anti-α Monoclonal Antibodies*

1990 • 16 citations

OBSERVATIONS ON THE ASSAY OF HUMAN URINARY FOLLICLE-STIMULATING HORMONE BY THE AUGMENTATION TEST IN MICE

1966 • 15 citations

Epitope mapping of the receptor-bound agonistic form of human chorionic gonadotropin (hCG) in comparison to the antagonistic form (deglycosylated hCG)

1991 • 15 citations

Synthetic human follicle-stimulating hormone-beta-(1-15) peptide-amide binds Ca2+ and possesses sequence similarity to calcium binding sites of calmodulin.

1992 • 14 citations

DISULFIDE BONDS OF GLYCOPROTEIN HORMONES: Their Selective Reduction in the β Subunits of Bovine Lutropin and Thyrotropin

1981 • 13 citations

Cloning and DNA sequence analysis of the cDNA for the precursor of porcine luteinizing hormone (LH) β subunit

1989 • 12 citations

Studies of human pituitary LH containing internally cleaved β subunit

1991 • 12 citations

Structure of a receptor-binding fragment from human luteinizing hormone beta-subunit determined by [1H]- and [15N]nuclear magnetic resonance spectroscopy.

1992 • 11 citations

Nucleic acid and amino acid sequences of dog βLH: comparison to rat, cow and human βLH

1987 • 11 citations

An antipodean perception of the mode of action of glycoprotein hormones

1992 • 9 citations

PURIFICATION AND PROPERTIES OF THE SUBUNITS OF HUMAN PITUITARY FOLLICLE-STIMULATING HORMONE

1976 • 8 citations

THYROID-STIMULATING AND LIPOLYTIC ACTIVITIES OF PURIFIED PREPARATIONS OF HUMAN THYROID-STIMULATING HORMONE

1972 • 8 citations

Heterogeneity of free alpha-subunit in term placenta.

1983 • 8 citations

Primary structure of sperm whale luteinizing hormone

1986 • 8 citations

Human luteinizing hormone. Structure and function of some preparations.

1977 • 8 citations

Reevaluation of the amino acid sequence of porcine follitropin

1989 • 6 citations

SIALIC ACID AND TRYPTOPHAN CONTENT OF SUBUNITS OF HUMAN PITUITARY LUTEINIZING HORMONE

1973 • 5 citations

Incompletely processed LH molecules synthesized by rat gonadotrophs treated with inhibitors of oligosaccharide processing

1989 • 4 citations

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