AF6q21, a Novel Partner of the MLL Gene in t(6; 11)(q21; q23), Defines a Forkhead Transcriptional Factor Subfamily

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

1993 • 884 citations

The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo

1989 • 760 citations

Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma.

1994 • 580 citations

Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head.

1991 • 517 citations

HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally.

1990 • 466 citations

Purification of CpG islands using a methylated DNA binding column

1994 • 449 citations

Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.

1994 • 430 citations

Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function.

1993 • 329 citations

The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family.

1996 • 300 citations

Report of the committee on chromosome changes in neoplasia

1990 • 249 citations

Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

1997 • 247 citations

Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family.

1993 • 237 citations

Molecular basis of IIq23 rearrangements in hematopoietic malignant proliferations

1995 • 211 citations

Balanced translocations involving chromosome bands 11q23 and 21q22 are highly characteristic of myelodysplasia and leukemia following therapy with cytostatic agents targeting at DNA-topoisomerase II [letter]

1991 • 210 citations

Hepatocyte nuclear factor 3 beta contains two transcriptional activation domains, one of which is novel and conserved with the Drosophila fork head protein.

1992 • 188 citations

Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.

1993 • 174 citations

Cloning and characterization of the t(X;II) breakpoint from a leukemic cell line identify a new member of the forkhead gene family

1994 • 155 citations

The Drosophila trithorax gene encodes a chromosomal protein and directly regulates the region-specific homeotic gene fork head.

1994 • 125 citations

Report of the committee on chromosome changes in neoplasia

1991 • 113 citations

A novel gene, AF-1p, fused to HRX in t(1;11)(p32;q23), is not related to AF-4, AF-9 nor ENL.

1994 • 111 citations

The retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork head.

1993 • 110 citations

Simultaneous localization of cosmids and chromosome R-banding by fluorescence microscopy: application to regional mapping of human chromosome 11.

1990 • 106 citations

Structural characterization of the FKHR gene and its rearrangement in alveolar rhabdomyosarcoma

1995 • 58 citations

The der(II) chromosome contains the critical breakpoint junction in the 4;11, 9;11, and 11;19 translocations in acute leukemia

1992 • 57 citations

Drosophila forkhead homologues are expressed in a lineage-restricted manner in human hematopoietic cells

1993 • 31 citations

Chromosome abnormalities in leukaemia: the 11q23 paradigm.

1996 • 25 citations

Cytogenetic and molecular analysis of chromosome 11q23 abnormalities in leukaemia

1992 • 21 citations