Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

The role of protein phosphorylation in neural and hormonal control of cellular activity

1982 • 1,116 citations

Role of ion flux in the control of c-fos expression

1986 • 1,006 citations

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells.

1985 • 888 citations

The Nerve Growth Factor: Biochemistry, Synthesis, and Mechanism of Action

1980 • 733 citations

PC12 Pheochromocytoma Cultures in Neurobiological Research

1982 • 728 citations

Reconstituted rattail collagen used as substrate for tissue cultures on coverslips in Maximow slides and roller tubes.

1958 • 660 citations

Identification of a calcium-binding protein as a calcium-dependent regulator of brain adenylate cyclase.

1975 • 546 citations

Interleukin-2 stimulates association of protein kinase C with plasma membrane

1985 • 384 citations

Allosteric regulation of the epidermal growth factor receptor kinase.

1986 • 381 citations

Protein phosphorylation in the nervous system

1984 • 329 citations

Nerve growth factor mediates phosphorylation of specific proteins

1980 • 305 citations

The epidermal growth factor-induced calcium signal in A431 cells.

1986 • 297 citations

Alterations in the surface properties of cells responsive to nerve growth factor

1978 • 279 citations

Identification of calmodulin-dependent protein kinase III and its major Mr 100,000 substrate in mammalian tissues.

1985 • 217 citations

Regulation of a high molecular weight microtubule-associated protein in PC12 cells by nerve growth factor.

1983 • 207 citations

Down regulation of protein kinase C in neuronal cells: effects on neurotransmitter release

1987 • 204 citations

Protein kinase C as a component of a nerve growth factor-sensitive phosphorylation system in PC12 cells.

1986 • 197 citations

Protein phosphorylation in the nervous system.

1985 • 177 citations

Troponin C-like proteins (calmodulins) from mammalian smooth muscle and other tissues

1979 • 177 citations

Nerve growth factor action is mediated by cyclic AMP- and Ca+2/phospholipid-dependent protein kinases.

1986 • 169 citations

The role of cAMP in nerve growth factor-promoted neurite outgrowth in PC12 cells.

1986 • 161 citations

Purification and properties of bovine brain calmodulin-dependent cyclic nucleotide phosphodiesterase.

1980 • 157 citations

Induction of c-fos and c-myc mRNA by epidermal growth factor or calcium ionophore is cAMP dependent.

1986 • 151 citations

Ionic responses and growth stimulation induced by nerve growth factor and epidermal growth factor in rat pheochromocytoma (PC12) cells.

1983 • 150 citations

Nerve growth factor in mouse saliva. Rapid isolation procedures for and characterization of 7 S nerve growth factor

1978 • 138 citations

Increased phosphorylation of specific nuclear proteins in superior cervical ganglia and PC12 cells in response to nerve growth factor.

1980 • 132 citations

Rapid activation of calmodulin-dependent protein kinase III in mitogen-stimulated human fibroblasts. Correlation with intracellular Ca2+ transients.

1987 • 129 citations

Calcium-Dependent Nerve Growth Factor-Stimulated Hydrolysis of Phosphoinositides in PC12 Cells

1987 • 127 citations

Nerve growth factor-inducible large external (NILE) glycoprotein: studies of a central and peripheral neuronal marker

1983 • 106 citations

Differential inhibition of nerve growth factor and epidermal growth factor effects on the PC12 pheochromocytoma line.

1984 • 102 citations

Alterations of Lipid Metabolism in Response to Nerve Growth Factor

1982 • 97 citations

Nerve growth factor-induced increase in the cell-free phosphorylation of a nuclear protein in PC12 cells.

1985 • 92 citations

Early rise of cytosolic Ca²⁺ induced by NGF in PC12 and chromaffin cells

1986 • 89 citations

Nerve growth factor modulates the drug sensitivity of neurotransmitter release from PC-12 cells.

1986 • 84 citations

Nerve growth factor- and epidermal growth factor-stimulated phosphorylation of a PC12 cytoskeletally associated protein in situ.

1985 • 83 citations

Rapid stimulation by nerve growth factor of amino acid uptake by clonal PC12 pheochromocytoma cells.

1979 • 79 citations

Possibility of shape conformers of the protein inhibitor of the cyclic adenosine monophosphate-dependent protein kinase

1979 • 71 citations

Ca2+ transmembrane fluxes and nerve growth factor action on a clonal cell line of rat phaeochromocytoma

1980 • 66 citations

Nerve growth factor-induced decrease in the cell-free phosphorylation of a soluble protein in PC12 cells.

1983 • 56 citations

The Induction of Ornithine Decarboxylase by Nerve Growth Factor and Epidermal Growth Factor in PC 12 Cells

1981 • 54 citations

Presence in many mammalian tissues of an identical major cytosolic substrate (M_r 100000) for calmodulin‐dependent protein kinase

1983 • 54 citations

Synapsin I in PC12 cells. I. Characterization of the phosphoprotein and effect of chronic NGF treatment

1987 • 52 citations

Partial purification and characterization of a nerve growth factor-sensitive kinase and its substrate from PC12 cells.

1985 • 47 citations

Rapid Activation of Tyrosine Hydroxylase in Response to Nerve Growth Factor

1984 • 46 citations

Synapsin I in PC12 cells. II. Evidence for regulation by NGF of phosphorylation at a novel site

1987 • 44 citations

Nerve Growth Factor Affects Cyclic AMP Metabolism, but Not by Directly Stimulating Adenylate Cyclase Activity

1985 • 38 citations

Regulation of Nerve Growth Factor Action on Nsp100 Phosphorylation in PC12h Cells by Calcium

1986 • 37 citations

Increased Levels of Neuron‐Specific Enolase in PC 12 Pheochromocytoma Cells as a Result of Nerve Growth Factor Treatment

1982 • 32 citations

A Nerve Growth Factor‐Sensitive S6 Kinase in Cell‐Free Extracts from PC 12 Cells

1986 • 29 citations

Inhibition of the phosphorylation of a 1000,000-dalton soluble protein in whole cells and cell-free extracts of PC12 pheochromocytoma cells following treatment with nerve growth factor.

1982 • 24 citations

Nerve growth factor does not activate Na⁺/H⁺ exchange in PC12 pheochromocytoma cells

1985 • 20 citations