Cutting Edge: Opposite Effects of IL-1 and IL-2 on the Regulation of IL-17+ T Cell Pool IL-1 Subverts IL-2-Mediated Suppression

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

2006 • 6,720 citations

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

2006 • 4,815 citations

Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

2005 • 4,573 citations

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

2005 • 3,961 citations

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

2006 • 3,545 citations

Transforming growth factor-β induces development of the TH17 lineage

2006 • 3,014 citations

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

2003 • 2,856 citations

Interleukin-17 Family Members and Inflammation

2004 • 2,340 citations

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

2006 • 2,234 citations

Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17

2003 • 1,828 citations

Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

2006 • 1,806 citations

Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation

2003 • 1,652 citations

IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis

2006 • 1,520 citations

Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation

2007 • 1,443 citations

Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties

2006 • 1,403 citations

Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity

2003 • 1,255 citations

A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis

2006 • 987 citations

IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist

2003 • 488 citations

Diversification of T-helper-cell lineages: finding the family root of IL-17-producing cells

2006 • 482 citations

Cutting Edge: Th17 and Regulatory T Cell Dynamics and the Regulation by IL-2 in the Tumor Microenvironment

2007 • 410 citations

TLR4 Mediates Vaccine-Induced Protective Cellular Immunity to Bordetella pertussis: Role of IL-17-Producing T Cells

2006 • 349 citations

Patients With Melanoma Metastases at Cutaneous and Subcutaneous Sites Are Highly Susceptible to Interleukin-2–Based Therapy

2001 • 46 citations