Definition of the human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex protein activation domain by functional exchange

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

1989 • 742 citations

Regulation by HIV Rev depends upon recognition of splice sites

1989 • 517 citations

HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: Implications for HIV-1 latency

1991 • 422 citations

Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes

1988 • 397 citations

Sequence-specific RNA binding by the HIV-1 Rev protein

1989 • 384 citations

Specific binding of HIV-1 recombinant Rev protein to the Rev-responsive element in vitro

1989 • 377 citations

Cells nonproductively infected with HIV-1 exhibit an aberrant pattern of viral RNA expression: A molecular model for latency

1990 • 371 citations

HIV-1 regulator of virion expression (Rev) protein binds to an RNA stem-loop structure located within the Rev response element region

1990 • 354 citations

Sequence requirements for nucleolar localization of human T cell leukemia virus type I pX protein, which regulates viral RNA processing

1988 • 308 citations

Mutational definition of the human immunodeficiency virus type 1 Rev activation domain

1991 • 276 citations

Identification of sequences important in the nucleolar localization of human immunodeficiency virus Rev: relevance of nucleolar localization to function

1990 • 257 citations

Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein

1988 • 216 citations

Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements.

1989 • 188 citations

Effector domains of human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex are functionally interchangeable and share an essential peptide motif

1991 • 147 citations

Characterization of HIV-1 REV protein: binding stoichiometry and minimal RNA substrate

1991 • 143 citations

Identification oftrans-dominant HIV-1 rev protein mutants by direct transfer of bacterially produced proteins into human cells

1990 • 128 citations

Regulation of HIV and HTLV gene expression.

1988 • 128 citations

Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action.

1990 • 119 citations

The type I human T-cell leukemia virus (HTLV-I) Rex trans-activator binds directly to the HTLV-I Rex and the type 1 human immunodeficiency virus Rev RNA response elements.

1991 • 83 citations

Functional mapping of the human immunodeficiency virus type 1 Rev RNA binding domain: new insights into the domain structure of Rev and Rex

1991 • 79 citations

Functional analysis of human T-cell leukemia virus type I rex-response element: direct RNA binding of Rex protein correlates with in vivo activity

1991 • 76 citations

Trans-dominant inactivation of HTLV-I and HIV-1 gene expression by mutation of the HTLV-I Rex transactivator

1989 • 73 citations

Cross-activation of the Rex proteins of HTLV-I and BLV and of the Rev protein of HIV-1 and nonreciprocal interactions with their RNA responsive elements.

1989 • 65 citations

Different sites of interaction for Rev, Tev, and Rex proteins within the Rev-responsive element of human immunodeficiency virus type 1

1990 • 63 citations

The Rex regulatory protein of human T-cell lymphotropic virus type I binds specifically to its target site within the viral RNA.

1991 • 47 citations

Leucine periodicity of U2 small nuclear ribonucleoprotein particle (snRNP) A' protein is implicated in snRNP assembly via protein-protein interactions.

1991 • 46 citations

Transdominant repressors for human T-cell leukemia virus type I rex and human immunodeficiency virus type 1 rev function

1991 • 43 citations

Mutational analysis of the human T-cell leukemia virus type I trans-acting rex gene product

1991 • 26 citations

Leucine Periodicity of U2 Small Nuclear Ribonucleoprotein Particle (snRNP) A' Protein Is Implicated in snRNP Assembly via Protein-Protein Interactions

1991 • 17 citations