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The Rex regulatory protein of human T-cell lymphotropic virus type I binds specifically to its target site within the viral RNA.

Data up to Jan 2025

Published1991
Citations47
References46

Total Citations Per Year

Abstract

References (46)

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA.

1983 • 1,555 citations

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

1989 • 742 citations

rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA.

1989 • 634 citations

Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs

1986 • 490 citations

HIV-1 structural gene expression requires binding of the rev trans-activator to its RNA target sequence

1990 • 457 citations

Cloning and functional analysis of multiply spliced mRNA species of human immunodeficiency virus type 1

1990 • 430 citations

The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization

1989 • 400 citations

Sequence-specific RNA binding by the HIV-1 Rev protein

1989 • 384 citations

Specific binding of HIV-1 recombinant Rev protein to the Rev-responsive element in vitro

1989 • 377 citations

Regulation of human immunodeficiency virus env expression by the rev gene product

1989 • 365 citations

The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region

1989 • 359 citations

Intragenic cis-acting art gene-responsive sequences of the human immunodeficiency virus.

1988 • 355 citations

HIV-1 regulator of virion expression (Rev) protein binds to an RNA stem-loop structure located within the Rev response element region

1990 • 354 citations

Identification of sequences important in the nucleolar localization of human immunodeficiency virus Rev: relevance of nucleolar localization to function

1990 • 257 citations

Env and Vpu proteins of human immunodeficiency virus type 1 are produced from multiple bicistronic mRNAs

1990 • 250 citations

Transcriptional (p40x) and post-transcriptional (p27x-III) regulators are required for the expression and replication of human T-cell leukemia virus type I genes.

1987 • 245 citations

Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants.

1988 • 228 citations

Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein

1988 • 216 citations

Interaction of the human immunodeficiency virus type 1 Rev protein with a structured region in env mRNA is dependent on multimer formation mediated through a basic stretch of amino acids.

1990 • 205 citations

Secondary Structure is the Major Determinant for Interaction of HIV rev Protein with RNA

1990 • 188 citations

Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements.

1989 • 188 citations

p27x-III and p21x-III, proteins encoded by the pX sequence of human T-cell leukemia virus type I.

1985 • 166 citations

Specific interaction of the human immunodeficiency virus Rev protein with a structured region in the env mRNA.

1990 • 166 citations

Functional Analysis of CAR, the Target Sequence for the Rev Protein of HIV-1

1989 • 152 citations

Feedback regulation of human immunodeficiency virus type 1 expression by the Rev protein

1990 • 130 citations

Identification oftrans-dominant HIV-1 rev protein mutants by direct transfer of bacterially produced proteins into human cells

1990 • 128 citations

Regulation of HIV-1 Gene Expression

1990 • 122 citations

Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action.

1990 • 119 citations

Human immunodeficiency virus rev protein recognizes a target sequence in rev-responsive element RNA within the context of RNA secondary structure

1990 • 102 citations

trans-acting regulation of bovine leukemia virus mRNA processing

1988 • 100 citations

Structural and functional characterization of the human immunodeficiency virus rev protein.

1989 • 100 citations

Regulation of expression of human immunodeficiency virus.

1990 • 98 citations

Expression of human immunodeficiency virus type 1 vif and vpr mRNAs is rev-dependent and regulated by splicing

1991 • 94 citations

The second pX product p27x‐III of HTLV‐1 is required for gag gene expression

1986 • 82 citations

Secondary structure of the human T-cell leukemia virus type 1 rex-responsive element is essential for rex regulation of RNA processing and transport of unspliced RNAs

1990 • 79 citations

Cis-acting sequences responsive to the rev gene product of the human immunodeficiency virus.

1988 • 75 citations

Trans-dominant inactivation of HTLV-I and HIV-1 gene expression by mutation of the HTLV-I Rex transactivator

1989 • 73 citations

Cross-activation of the Rex proteins of HTLV-I and BLV and of the Rev protein of HIV-1 and nonreciprocal interactions with their RNA responsive elements.

1989 • 65 citations

Different sites of interaction for Rev, Tev, and Rex proteins within the Rev-responsive element of human immunodeficiency virus type 1

1990 • 63 citations

HTLV-I p27rex regulates gag and env protein expression.

1989 • 41 citations

Binding of trans-dominant mutant Rev protein of human immunodeficiency virus type 1 to the cis-acting Rev-responsive element does not affect the fate of viral mRNA.

1990 • 31 citations

HTLV-I p27rex regulates gag and env protein expression.

1989 • 29 citations

Rous sarcoma virus contains sequences which permit expression of the gag gene in Escherichia coli.

1983 • 27 citations

Rous Sarcoma Virus Contains Sequences Which Permit Expression of the gag Gene in Escherichia coli

1983 • 11 citations

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The Rex regulatory protein of human T-cell lymphotropic virus type I binds specifically… (1991) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer