Cloning and characterization of cDNA encoding 3-methylcholanthrene inducible rat mRNA for UDP-glucuronosyltransferase.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

A system for shotgun DNA sequencing

1981 • 2,710 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Atlas of Protein Sequence and Structure, 1972.

1973 • 2,408 citations

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

1984 • 1,386 citations

Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components.

1975 • 1,175 citations

Magnesium precipitation of ribonucleoprotein complexes. Expedient techniques for the isolation of undegraded polysomes and messenger ribonucleic acid

1974 • 987 citations

Mechanisms for the incorporation of proteins in membranes and organelles.

1982 • 875 citations

Protein translocation across the endoplasmic reticulum

1984 • 825 citations

Glucuronidation of Drugs and Other Compounds

2019 • 807 citations

Polycyclic Hydrocarbons and Cancer

1981 • 737 citations

Enzymatic Basis of Detoxication

1980 • 717 citations

The class II molecules of the human and murine major histocompatibility complex

1984 • 664 citations

Molecular cloning of cDNA encoding human interleukin-2 receptor

1984 • 567 citations

Amino-acid sequence and oligosaccharide attachment sites of human erythrocyte glycophorin.

1975 • 533 citations

5′-Terminal sequences of eucaryotic mRNA can be cloned with high efficiency

1981 • 367 citations

Biosynthesis of lysosomal hydrolases: their synthesis in bound polysomes and the role of co- and post-translational processing in determining their subcellular distribution

1982 • 246 citations

The Solubilization and Partial Purification of a Glucuronyl Transferase from Rabbit Liver Microsomes

1962 • 235 citations

Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase

1973 • 229 citations

Assay and properties of digitonin-activated bilirubin uridine diphosphate glucuronyltransferase from rat liver

1972 • 229 citations

Purification of Rat‐Liver Microsomal UDP‐glucuronyltransferase

1979 • 219 citations

Structural features of liver microsomal NADPH-cytochrome P-450 reductase. Hydrophobic domain, hydrophilic domain, and connecting region.

1982 • 173 citations

Rat liver UDP-glucuronosyltransferase. Sequence and expression of a cDNA encoding a phenobarbital-inducible form.

1986 • 171 citations

Separation, purification and characterization of three isoenzymes of UDP-glucuronyltransferase from rat liver microsomes

1983 • 159 citations

Structural Characteristics of Cytochrome P-450. Possible Location of the Heme-Binding Cysteine in Determined Amino-Acid Sequences

1983 • 146 citations

Coding nucleotide sequence of 3-methylcholanthrene-inducible cytochrome P-450d cDNA from rat liver.

1984 • 129 citations

Nucleotide sequence of a full-length cDNA coding for 3-methylcholanthrene-induced rat liver cytochrome P-450MC

1984 • 129 citations

Regulatory DNA elements localized remotely upstream from the drug-metabolizing cytochrome P-450c gene

1986 • 128 citations

Demonstration of functional heterogeneity of hepatic uridine diphosphate glucuronosyltransferase activities after administration of 3-methylcholanthrene and phenobarbital to rats

1978 • 124 citations

Purification and properties of microsomal UDP-glucuronosyltransferase from rat liver.

1977 • 106 citations

Complete nucleotide sequence of a methylcholanthrene-inducible cytochrome P-450 (P-450d) gene in the rat.

1985 • 104 citations

Distribution of UDPglucuronosyltransferase in rat tissue.

1985 • 101 citations

Microsequence analysis of peptides and proteins

1985 • 94 citations

Studies on Microsomal Nucleoside Diphosphatase of Rat Hepatocytes

1972 • 84 citations

The full length coding sequence of rat liver androsterone UDP-glucuronyltransferase cDNA and comparison with other members of this gene family

1986 • 81 citations

Substrate specificity and properties of uridine diphosphate glucuronyltransferase purified to apparent homogeneity from phenobarbital-treated rat liver

1978 • 81 citations

Isolation and characterization of multiple forms of rat liver UDP-glucuronate glucuronosyltransferase

1986 • 80 citations

Titration of mRNAs for cytochrome P-450c and P-450d under drug-inductive conditions in rat livers by their specific probes of cloned DNAs.

1984 • 69 citations

The covalent structure of rabbit phenobarbital-induced cytochrome P-450. Partial amino acid sequence and order of cyanogen bromide peptides.

1982 • 63 citations

Multiplicity of deoxyribonucleic acid sequences with homology to a cloned complementary deoxyribonucleic acid coding for rat phenobarbital-inducible cytochrome P-450

1983 • 63 citations

Cloning and characterization of DNA complementary to rat liver UDP-glucuronosyltransferase mRNA.

1984 • 62 citations

Structural analysis of NADPH-cytochrome P-450 reductase from porcine hepatic microsomes. Sequences of proteolytic fragments, cysteine-containing peptides, and a NADPH-protected cysteine peptide.

1984 • 50 citations

The separation and purification of rat liver UDP-glucuronyltransferase activities towards testosterone and oestrone

1980 • 46 citations

Purification of UDP‐glucuronyltransferase from untreated rat liver

1977 • 43 citations

Differential regulation by triiodothyronine of substrate-specific uridinediphosphoglucuronate glucuronosyl transferases in rat liver

1983 • 40 citations

Genetic deficiency of androsterone UDP-glucuronosyltransferase activity in Wistar rats is due to the loss of enzyme protein

1986 • 32 citations

Evidence for an active site arginine in UDP-glucuronyltransferase.

1983 • 28 citations