Transmembrane orientation of the mannose 6-phosphate receptor in isolated clathrin-coated vesicles.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Lysosomes in biology and pathology

1977 • 2,068 citations

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

1984 • 1,386 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight.

1980 • 809 citations

The biochemistry of glycoproteins and proteoglycans

1980 • 651 citations

Membrane Recycling by Coated Vesicles

1981 • 450 citations

The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence

1984 • 337 citations

The mannose-6-phosphate receptor for lysosomal enzymes is concentrated in cis Golgi cisternae

1984 • 291 citations

Evidence for extensive subcellular organization of asparagine-linked oligosaccharide processing and lysosomal enzyme phosphorylation.

1983 • 270 citations

Biosynthesis of lysosomal hydrolases: their synthesis in bound polysomes and the role of co- and post-translational processing in determining their subcellular distribution

1982 • 246 citations

Early events in the biosynthesis of the lysosomal enzyme cathepsin D.

1979 • 233 citations

Primary structure of the rat liver asialoglycoprotein receptor. Structural evidence for multiple polypeptide species.

1984 • 219 citations

Acidification of endocytic vesicles by an ATP-dependent proton pump.

1983 • 217 citations

Biosynthesis of a lysosomal enzyme. Partial structure of two transient and functionally distinct NH2-terminal sequences in cathepsin D.

1981 • 188 citations

Characterization of a membrane-associated receptor from bovine liver that binds phosphomannosyl residues of bovine testicular beta-galactosidase.

1981 • 176 citations

Immunoblot analysis of low density lipoprotein receptors in fibroblasts from subjects with familial hypercholesterolemia.

1982 • 175 citations

Identification of a rat liver alpha-N-acetylglucosaminyl phosphodiesterase capable of removing “blocking” alpha-N-acetylglucosamine residues from phosphorylated high mannose oligosaccharides of lysosomal enzymes.

1980 • 174 citations

Biosynthesis and turnover of the mannose 6-phosphate receptor in cultured Chinese hamster ovary cells.

1983 • 169 citations

HISTOCHEMICAL DEMONSTRATION OF NORADRENALINE AND ADRENALINE IN THE ADRENAL MEDULLA

1955 • 165 citations

Ultrastructural localization of the mannose 6-phosphate receptor in rat liver.

1984 • 162 citations

Morphologic study of the internalization of a lysosomal enzyme by the mannose 6-phosphate receptor in cultured Chinese hamster ovary cells.

1981 • 131 citations

Rat liver asialoglycoprotein receptor lacks a cleavable NH2-terminal signal sequence.

1984 • 124 citations

Fusion of coated vesicles with lysosomes: Measurement with a fluorescence assay

1983 • 113 citations

An alternative hypothesis of cellular transport of lysosomal enzymes in fibroblasts. Effect of inhibitors of lysosomal enzyme endocytosis on intra- and extra-cellular lysosomal enzyme activities

1978 • 111 citations

Instability of coated vesicles in concentrated sucrose solutions.

1982 • 111 citations

Synthesis of phosphorylated recognition marker in lysosomal enzymes is located in the cis part of Golgi apparatus.

1982 • 106 citations

Detection of membrane cholesterol by filipin in isolated rat liver coated vesicles is dependent upon removal of the clathrin coat.

1984 • 89 citations

Subcellular location of two enzymes involved in the synthesis of phosphorylated recognition markers in lysosomal enzymes.

1981 • 85 citations

Assay and purification of a solubilized membrane receptor that binds the lysosomal enzyme α-l-iduronidase

1982 • 79 citations

Excretion-Reuptake Route of β-Hexosaminidase in Normal and I-Cell Disease Cultured Fibroblasts

1979 • 76 citations

The mannose 6‐phosphate receptor: function, biosynthesis and translocation

1984 • 73 citations

[34] Membrane receptor for phosphomannosyl residues

1982 • 65 citations

Coated vesicles from rat liver and calf brain contain cryptic mannose 6-phosphate receptors.

1983 • 62 citations

Ultrastructural immunocytochemical localization of the phosphomannosyl receptor in Chinese hamster ovary (CHO) cells.

1983 • 61 citations

Coated vesicles from rat liver and calf brain contain lysosomal enzymes bound to mannose 6-phosphate receptors.

1983 • 58 citations

Isolation of lysosomal α-mannosidase mutants of Chinese hamster ovary cells

1979 • 57 citations

Mannose 6-phosphate-specific receptor is a transmembrane protein with a C-terminal extension oriented towards the cytosol

1985 • 49 citations

Clathrin-Coated Pits and Coated Vesicles: Functional and Structural Studies

2007 • 41 citations

Interaction of liver clathrin coat protein with lipid model membranes.

1982 • 37 citations

Brain clathrin and clathrin-associated proteins.

1982 • 29 citations

Brain Clathrin: Studies of Its Ultrastructural Assemblies

1982 • 24 citations

Membrane lipid response to clathrin coat protein determined by infrared spectroscopy. Possible involvement in coated vesicle formation.

1984 • 11 citations